What is Tresiba insulin?
Tresiba (insulin degludec) is a long-acting, man-made insulin designed to help control blood sugar levels in people with diabetes mellitus who are one year old or older.
Diabetes mellitus is a condition where your body either does not make enough insulin or cannot use it properly, leading to high blood sugar.
Tresiba works steadily throughout the day and night to maintain stable blood sugar levels.
It comes in two concentrations: U-100, which can be injected in doses from 1 to 80 units, and U-200, which allows 2 to 160 units.
Doctors do not recommend Tresiba for treating diabetic ketoacidosis, a severe condition where harmful substances called ketones build up in the blood.
How Does Tresiba Work?
Tresiba acts like your body’s insulin to help control blood sugar levels.
Tresiba helps your body move sugar from your blood into your muscles and fat cells for energy and storage. It also stops your liver from producing too much sugar.
This slow and consistent release allows Tresiba to work up to 42 hours, offering stable blood sugar management throughout the day and night.
Dosage Information and Usage
Tresiba is a long-acting insulin used to help control blood sugar levels in people with diabetes. It maintains steady blood sugar for up to 42 hours, making it ideal for once-daily dosing.
This medication has multiple strengths to suit individual treatment needs, ensuring flexibility and effective glycemic control.
Dosage Form and Strengths of Tresiba
Tresiba is available in two strengths to meet individual patient needs:
- 3 mL FlexTouch pen:
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- U-100 (100 units/mL) delivers doses in 1-unit increments, up to 80 units per injection. This format is ideal for those needing smaller or more precise insulin doses.
- U-200 (200 units/mL) delivers doses in 2-unit increments, up to 160 units per injection. This dosage is for patients requiring higher insulin doses with fewer injections.
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- 10 mL vial:
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- U-100 (100 units/mL) is suitable for U-100 syringes. It is commonly used in clinics or by patients who prefer drawing insulin manually.
How to Use Tresiba?
Properly using Tresiba is crucial for managing diabetes effectively and safely.
Here is how to use Tresiba step-by-step for optimal results:
- Wash your hands thoroughly to maintain hygiene. Check the Tresiba solution to ensure it is clear and colorless.
- Inject Tresiba subcutaneously into your thigh, upper arm, or abdomen. Rotate injection sites within the same area to prevent skin issues like lumps or thickened skin.
- Use the FlexTouch pen or syringe as your doctor instructed. If you miss a dose, take it as soon as possible, ensuring there is at least an 8-hour gap before the next dose.
- Safely dispose of needles in a sharps container to avoid injury. Regularly monitor your blood sugar level.
Important notes when using Tresiba:
- Avoid injecting into veins or muscles, as Tresiba is designed for subcutaneous use.
- Do not mix Tresiba with other insulins or solutions to maintain its effectiveness.
- For children requiring less than five units daily, use the U-100 vial for precise dosing.
Side Effects
Like all medications, Tresiba can cause side effects that vary in severity. Common side effects include headache, diarrhea, and low blood sugar, while severe side effects could involve symptoms such as seizures, blurred vision, or irregular heartbeat.
Below are the most commonly reported and rare but severe side effects that may require immediate medical attention.
Common Side Effects
- Headache
- Diarrhea
- Common cold symptoms
- Low blood sugar (hypoglycemia)
- Redness or swelling at the injection site
- Dizziness
- Increased or decreased appetite
Severe Side Effects
- Anxiety
- Blurred vision
- Seizures
- Irregular or fast heartbeat
- Chest tightness or difficulty breathing
- Unusual weight gain or loss
Warnings and Precautions
Following safety guidelines and precautions when using Tresiba is important to ensure effective and safe diabetes management. While Tresiba helps control blood sugar, there are specific warnings to be aware of, such as avoiding sharing insulin pens, recognizing the risks of hypoglycemia, and understanding the potential for medication errors.
- Never share Tresiba pens or syringes: Do not share your Tresiba pen, syringe, or needle with anyone, even if the needle is changed. Sharing can spread infections, especially blood-borne diseases like HIV or hepatitis.
- Changes in insulin regimen: Any changes to your insulin treatment can affect your blood sugar levels. These changes may cause your blood sugar to go too high (hyperglycemia) or too low (hypoglycemia).
- Hypoglycemia (low blood sugar): Low blood sugar is a common risk with insulin, including Tresiba. Symptoms may include dizziness, confusion, sweating, and shaking. Severe hypoglycemia can be dangerous, leading to seizures, unconsciousness, or even death.
- Mistakes when taking the medication: To avoid errors, always double-check your insulin label before injecting. Never use a syringe to remove insulin from the Tresiba FlexTouch pen, as this can lead to incorrect dosing.
- Severe allergic reaction: Some people may experience severe allergic reactions, including swelling, trouble breathing, or rashes. If you are allergic to insulin or any part of Tresiba, stop using it immediately and seek medical attention.
- Hypokalemia (low potassium): Insulin can cause a drop in potassium levels, affecting your heart and muscles. If you are at risk for low potassium, such as taking medications that affect potassium, your doctor may monitor your potassium levels.
- Fluid retention and heart failure: If you take Tresiba with other medications called thiazolidinediones (used for diabetes), you may experience fluid retention. This can make heart failure worse.
Drug Interactions
When taking Tresiba, it is important to be aware of potential drug interactions that can affect its effectiveness. Some medications may increase the risk of low blood sugar (hypoglycemia), while others may reduce Tresiba’s effectiveness in lowering blood glucose.
Below are the drug interactions to Tresiba to be aware of:
Medications that may increase the risk of hypoglycemia:
- Antidiabetic agents (e.g., Metformin)
- ACE inhibitors (e.g., Lisinopril)
- Angiotensin II receptor blocking agents (e.g., Losartan)
- Disopyramide
- Fibrates (e.g., Fenofibrate)
- Fluoxetine
- Monoamine oxidase inhibitors (e.g., Phenelzine)
- Pentoxifylline
- Pramlintide
- Salicylates (e.g., Aspirin)
- Somatostatin analogs (e.g., Octreotide)
- Sulfonamide antibiotics (e.g., Trimethoprim/Sulfamethoxazole)
- GLP-1 receptor agonists (e.g., Liraglutide)
- DPP-4 inhibitors (e.g., Sitagliptin)
- SGLT-2 inhibitors (e.g., Empagliflozin)
Drugs that may increase or decrease blood glucose:
- Atypical antipsychotics (e.g., Olanzapine, Clozapine)
- Corticosteroids (e.g., Prednisone)
- Danazol
- Diuretics (e.g., Furosemide)
- Estrogens (e.g., in birth control pills)
- Glucagon
- Isoniazid
- Niacin
- Oral contraceptives (e.g., Ethinylestradiol)
- Phenothiazines (e.g., Chlorpromazine)
- Progestogens (e.g., in birth control pills)
- Protease inhibitors (e.g., Ritonavir)
- Somatropin
- Sympathomimetic agents (e.g., Albuterol, Epinephrine)
- Thyroid hormones (e.g., Levothyroxine)
- Alcohol
- Beta-blockers (e.g., Metoprolol)
- Clonidine
- Lithium salts
Alternative Medications
Tresiba is a common insulin used to manage diabetes, but some patients might opt for other options due to cost, side effects, or personal preference.
Several insulin medications, like Tresiba, work to regulate blood sugar levels. Here are the following Tresiba alternatives:
- Basaglar (insulin glargine)
- Novolog (insulin aspart)
- Levemir (insulin detemir)
Get Budget-Friendly Tresiba Products from Pharma Giant
If you are struggling with the high cost of Tresiba in the USA, Pharma Giant offers a cost-effective alternative.
In the United States, a 10-milliliter supply of Tresiba can cost up to $366, but by purchasing Tresiba from Canada, you can access this essential medication at a fraction of the price.
Pharma Giant offers affordable Tresiba products:
- Tresiba FlexTouch 100 (Insulin Degludec) 100 Units / mL – 5x3ml pens: $149.00 (originally $694.84)
- Tresiba FlexTouch 200 (Insulin Degludec) 200 Units / mL – 3x3ml pens: $179.00 (originally $812.09)
Through our network of experienced pharmacists and e-commerce specialists, Pharma Giant makes it easier for individuals with diabetes to obtain medications like Tresiba online from Canada without the financial burden.
When you purchase Tresiba from Pharma Giant, you can count on getting your medication delivered quickly and safely.
With our competitive pricing, exclusive discounts, referral programs, and fast shipping, Pharma Giant ensures you can afford the needed medications. Do not let the high price of insulin prevent you from managing your diabetes – order Tresiba from Canada today and start saving!
How to Order Tresiba Online?
Ordering Tresiba online is easy and secure. With Pharma Giant, you can conveniently order up to a 90-day supply, which is ideal for managing ongoing treatment and cost.
However, a valid prescription is required for Tresiba purchases to ensure patient safety and proper medical guidelines.
Follow these simple steps to order Tresiba online from Pharma Giant:
- Start by using the search field at the top of the website to find Tresiba or any other medication you need. Once you find the correct medication and dosage, click the ‘Buy’ button to add it to your cart.
- After adding Tresiba to your cart, proceed to checkout by entering your contact details, payment information, and shipping address. Create an account with your email address and password to access future orders and order status tracking. Once your payment is processed, you will receive an email confirmation with your order details, prescription information, and shipping details.
- As Tresiba is a prescription medication, you must send us a scanned copy or a high-quality digital photo of your prescription. You can easily upload it via the website’s RX document uploader tool or fax it to us at 1-888-234-1275.
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