Buy Aczone from Canada
From$119.95
$899.34
Aczone Dapsone
Select product strength & quantity:
Prescription Required
Ships within 4-10 Business Days
Express Ships from Canada
Product of Canada

What is Aczone (dapsone)?

Aczone Gel 5% (dapsone) is a topical prescription medication used to treat acne vulgaris, a common skin condition that causes pimples, blackheads, and whiteheads.

Aczone is known for reducing inflammation and fighting acne-causing bacteria without being absorbed much into the bloodstream, which lowers the risk of side effects.

Indications and Benefits of Aczone

  • Treats mild to moderate acne vulgaris
  • Helps reduce redness and swelling
  • Decreases acne-causing bacteria
  • Suitable for long-term treatment under medical supervision
  • Offers an alternative to oral antibiotics

How It Works

Aczone contains dapsone, an antibacterial and anti-inflammatory agent. It works by:

  • Killing acne-causing bacteria on the skin
  • Reducing redness, swelling, and irritation
  • Minimizing the formation of pimples and clogged pores

Because it is applied topically, only a small amount of dapsone is absorbed into the bloodstream, making it safer for many users.

Dosage

What Dosage Strengths Does Aczone Come In?

Aczone Gel 5% is available in a 60-gram tube. Each gram of the gel contains 50 milligrams of dapsone as the active ingredient.

Dosage Chart

Age Group Recommended Dosage
Adults & teens (12+) Apply a pea-sized amount to affected areas twice daily
Children under 12 Use only if prescribed by a healthcare provider

Usage Guide

Here is the step-by-step guide on how to use Aczone:

  1. Gently wash and dry your face
  2. Dispense a small, pea-sized amount of Aczone
  3. Apply to acne-prone areas
  4. Massage in gently until fully absorbed
  5. Avoid contact with eyes, lips, and mouth
  6. Wash your hands immediately afterward

Side Effects

Common Side Effects

  • Skin dryness
  • Redness or irritation
  • Oily skin
  • Peeling at the application site

Serious but Rare Side Effects

  • Methemoglobinemia (bluish lips or nails)
  • Hemolytic anemia in those with G6PD deficiency
    • Symptoms: fatigue, back pain, pale skin, shortness of breath
  • Allergic skin reactions (rash, peeling, burning)

Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed one. Do not double up on doses.

Overdose

Using too much Aczone can cause increased skin irritation or rare side effects, such as methemoglobinemia. Seek medical help immediately if symptoms like bluish lips or difficulty breathing occur.

Warnings

  • Aczone may cause methemoglobinemia, a condition that reduces the amount of oxygen that can be carried in the blood.
  • There is a risk of red blood cell damage in people with G6PD deficiency when using Aczone.
  • Do not apply Aczone to open wounds or broken skin.
  • Use Aczone only under medical supervision during pregnancy or while breastfeeding.
  • Do not use Aczone together with benzoyl peroxide, as it may cause skin or hair discoloration.

Boxed Warning and Precautions for Aczone

Aczone does not have a boxed warning, but take extra caution if:

  • You have G6PD deficiency
  • You are taking medications that can cause methemoglobinemia
  • You plan to use it with benzoyl peroxide (temporary yellow/orange discoloration may occur)

Contraindications

  • Do not use Aczone if you are allergic to dapsone or any of the ingredients in the gel.
  • People with G6PD deficiency, a condition where the body has trouble protecting red blood cells, should not use Aczone.
  • Avoid using Aczone if you are pregnant or breastfeeding, unless your doctor says it is safe for you.

Interactions

  • Trimethoprim-sulfamethoxazole (TMP/SMX)
  • Benzoyl peroxide
  • Sulfonamides
  • Acetaminophen
  • Nitrates
  • St. John’s wort
  • Rifampin
  • Anticonvulsants

Storage Information

Store Aczone Gel at room temperature between 68 degrees Fahrenheit and 77 degrees Fahrenheit or 20 degrees Celsius and 25 degrees Celsius.

Do not freeze the medication because freezing can damage the gel. Keep it out of the reach of children and pets to ensure safety.

Always close the cap tightly after each use to maintain the gel’s cleanliness and effectiveness.

Alternatives

  • Accutane (isotretinoin)
  • Cleocin T (clindamycin)
  • Aldactone (spironolactone)
  • Epiduo (adapalene and benzoyl peroxide)

Cost & Coupons

Buy Aczone Online from Canada

Buy Aczone online from Canada and save on your treatment. Pharma Giant offers Aczone Gel 5 percent in a 60-gram tube for only $119.95, compared to the average U.S. retail price of $628.22.

All medications are sourced from licensed Canadian pharmacies, with prescriptions issued by doctors and verified by pharmacists. You can also order a supply of up to three months for added convenience and even greater savings.

Aczone Discounts and Coupons from Pharma Giant

Use promo code PGSAVE10 at checkout to receive 10% off your first order of Aczone.

Aczone Pricing at Pharma Giant

Strength & Quantity Price (USD)
Aczone 5% – 60 g $119.95
Aczone 5% – 120 g $234.00
Aczone 5% – 180 g $345.00

Pharma Giant’s Guarantee

Don’t let the cost of medication stand between you and clear skin. Choose Pharma Giant for affordable solutions and better health management.

By choosing Pharma Giant, you ensure that your health is a priority without the worry of high costs. Get the medications you need, at a price you can afford.

Frequently Asked Questions

Aczone reduces the inflammation and the number of skin bacteria that are associated with acne.

Aczone works by killing the bacteria that cause acne, thereby reducing inflammation in the skin.

Generally, Aczone begins its improvement process after about 12 weeks.

Oral dapsone, chloroquine for malaria, trimethoprim/sulfamethoxazole, and benzoyl peroxide with Aczone should be avoided.

Yes, Aczone can be used alone or with other treatments for acne including topical antibiotics, which include erythromycin or clindamycin.

Use the cleanser for your face and pat it dry. Use a pea-sized portion of this gel over that area, spreading thin daily when you remove your makeup from that area.

If you miss one application of Aczone, use it as soon as possible. If it is nearly time for your next application, skip the missed application and go back to your regular schedule. Do not double up on your dose to make up for a missed dose.

Aczone is safe for your sensitive skin, but do not use this product if you ever had a past hypersensitivity reaction to Aczone.

The most common side effects of Aczone include localized dryness, redness, peeling, and oiliness at the application site.

If side effects of Aczone bother you, consult your doctor. Report all side effects to your doctor right away, especially signs of serious side effects, including unusual tiredness, dark urine, shortness of breath or your lips or nails becoming blue or gray.

You should take about 12 weeks of Aczone or 3 months. After that, you would have to consult with your doctor whether you can continue it.

Aczone is not recommended during pregnancy. Animal studies did not reveal the existence of birth defects, but research data are limited and physicians normally refrain from administering drugs to pregnant women.

Aczone should not be taken during breastfeeding. Any breastfeeding woman should, therefore, consider seeking her doctor’s opinion as to whether she should cease nursing while on the said medication.

Aczone interacts with many drugs which cause methemoglobinemia. Other drugs which interact include sulfonamides, acetaminophen, acetanilide, and aniline dyes. Other drugs used alongside Aczone include benzocaine, chloroquine, and dapsone. Naphthalene, nitrates and nitrites, nitrofurantoin, nitroglycerin, nitroprusside, pamaquine, para-aminosalicylic acid, phenacetin, and phenobarbital is just a partial list of other drugs used potentially harmful with the patient.

Aczone comes under the drug class Aczone is a sulfone drug. The medication applies topically in the treatment of patients with acne vulgaris. Dapsone is the main active ingredient of this medication.

Yes, Aczone does irritate the skin. Common side effects of the drug would include burning, itching, crusting, or peeling in the area of treatment. Allergic reaction symptoms include rash, hives, and swelling in the face, lips, tongue, or throat; it is best to consult your health crew.

Get rid of all your makeup and clean your face right before you place the Aczone gel on. Let the skin dry then apply a pea-sized amount of Aczone gel as a thin layer on your entire face once a day.

Store Aczone at room temperature, in a dry place, and outside heat. Keep the container of the gel tightly closed and out of reach of children. Do not freeze the gel.

Aczone is a prescription drug, applied topically to adult patients and older children 12 years of age or greater.

Aczone must be administered once daily to its maximum effect. A pea-sized quantity would do; apply it thinly as a layer all over the face.

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

Have a prescription?

Order Aczone online today and enjoy a host of benefits, including:

 Customer Reviews
  • Cost Savings: Buy Aczone at LOWER PRICES compared to the US
  • Bulk Order Discounts: Enjoy additional savings with bulk orders of Aczone (up to 90-day supply)
  • Reliable Express Shipping: Fast and discreet delivery shipped directly to your doorstep
  • Exceptional Customer Service: Have a question? We’re delighted to help via live chat, email, or phone
  • Easy & Secure Ordering: Seamless online or phone ordering at 1-888-513-2294
  • SAVE 10% on first order with coupon code: PGSAVE10

Price Match Guarantee

Price Match Guarantee

We are committed to providing fair, competitive pricing on all medications. If you find a lower price on the same product at another verified Canadian online pharmacy, we’ll match it.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online pharmacy with a verifiable address.
  • The competitor’s price must be current and active (not from a past or future promotion).
  • The product must be identical in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be submitted before placing an order — adjustments cannot be made after purchase.
  • Price matching does not apply to used or expired products.
  • Requests can be submitted via live chat or phone prior to completing your order.

Note: Price matching does not currently apply to Mounjaro® , Ozempic® or Saxenda®. However, this policy may be updated in the future.