
Prescription Required.
Product of Canada.
Shipped from Canada.
Prescription Required. | Product of Canada. | Shipped from Canada. |
Alvesco (Ciclesonide)
What is Alvesco?
The name of the group of medications that Alvesco, also known as Ciclesonide, belongs to is inhaled corticosteroids. Alvesco, approved by the FDA in January 2010, is used by adults and children aged at least six to treat their asthma. Alvesco helps to keep asthma symptoms under control and reduce inflammation in the lungs.
Once you begin taking it, Alvesco normally begins working within 24 hours, however, it may be up to 2 weeks before you begin to see its full effects. You should not take Alvesco expecting it to provide instant relief for an asthma attack that is already in progress. Alvesco is a long-term treatment that should be regularly complemented by other inhalers that provide faster relief, such as salbutamol, formoterol, or terbutaline.
How Alvesco works
Glucocorticoid steroids are powerful anti-inflammatories. While Alvesco, part of the glucocorticoid family, is a man-made steroid, it is related to the natural steroid hormone, cortisol, or hydrocortisone, which is supplied by the adrenal glands. Des-ciclesonide is produced by the body, which is the active form of the drug ciclesonide.
For asthmatics, Alvesco in its inhaler form targets the lungs and reduces inflammation in the airways. It helps to prevent muscle cells around the airways from spasming, cutting back on fluid and cells that can result in airways becoming narrow in the wake of inflammation. Narrowing airways means it can be difficult for the lungs to get air in and out.
At lower doses, the body does not absorb much Alvesco, however, more is absorbed when taking higher doses, potentially resulting in side effects.
Ingredients
50 µg
This form contains 50 µg of Alvesco per actuation. Its nonmedicinal ingredients include
propellant HFA-134a (Norflurane) and ethanol.
100 µg
This form contains 50 µg of Alvesco per actuation. Its nonmedicinal ingredients include propellant HFA-134a (Norflurane) and ethanol.
200 µg
This form contains 50 µg of Alvesco per actuation. Its nonmedicinal ingredients include propellant HFA-134a (Norflurane) and ethanol.
Dosage
The usual starting dose for adults and adolescents over the age of 12 is 400 µg taken daily. Thereafter, the usual daily dose is between 100 µg and 800 µg.
Most asthma patients will be able to take 1 or 2 puffs either each morning or night. Those whose asthma is more severe may require 800 µg each day, taken as two 400 µg puffs.
Children aged between 6 and 11 are usually prescribed 100 µg to 200 µg once a day, either as 1 or 2 puffs in the morning or at night.
You should determine the most suitable dose for you or your child by discussing it with your doctor. Your daily dose of Alvesco should be the lowest dose you can use to keep your asthma symptoms under control.
Alvesco is for preventing asthma attacks. It should not be used to relieve the symptoms of an attack that has begun. For this, you should use your reliever medication. If you do not have medication to relieve the symptoms of asthma attacks, you should discuss it with your doctor.
You should also discuss with them whether you might benefit from a spacer. In order for Alvesco to be as effective as possible, you need to get as much of your inhaled dose to your lungs as possible. Your doctor or pharmacist will be able to advise you on the best techniques for taking Alvesco, this might include using a spacer.
You do not need to shake your inhaler before using it.
Overdose
Life-threatening symptoms are not expected from an overdose of Alvesco. But using high doses of steroids over long periods of time can result in symptoms, such as:
- Thinning skin
- Easy bruising
- Displacement of body fat in the:
- face
- neck
- back
- waist
- More acne or facial hair
- Menstrual issues
- Impotence
- Reduced sexual appetite
If you believe you, or someone else, has overdosed on Alvesco, you should contact your doctor as soon as possible. If someone has collapsed or isn’t breathing after using Alvesco, you should contact the emergency services.
Side Effects
If you are concerned about experiencing side effects from taking Alvesco, you should talk it over with your doctor and weigh up the risks against the benefits. Many of these side effects may disappear over time or can be managed. Your pharmacist should be able to make recommendations for managing these side effects, however, you should contact your doctor if they become severe or significantly uncomfortable.
The side effects of Alvesco are not experienced by everyone who takes it, but at least 1% of people taking this medication have experienced those listed below.
- bad taste
- cough
- dry mouth or throat
- headache
- hoarseness or other voice changes
- increased blood pressure
- sore throat or tongue
More serious side effects
These serious side effects are rare but can cause serious issues if they are not addressed. If you experience any of these, you should see your doctor as soon as possible.
- abdominal pain
- high doses leading to decreased bone density
- eye pain
- pounding heartbeat
- high doses leading to a more rounded face
- changes in vision
- fungal infection symptoms in the mouth, such as white patches in the mouth and throat
Side effects requiring urgent medical attention
If you experience any of the following side effects, discontinue the treatment and immediately seek the attention of a medical professional.
- signs of a severe allergic reaction, such as:
- hives
- difficulty breathing
- swelling of:
- lips
- face
- eyelids
- throat
- or tongue
- sudden wheezing and chest pain or tightness
Side effects other than those listed above are possible. If any symptoms develop that worry you whilst taking Alvesco, you should discuss them with your doctor.
Warnings & Precautions
Always check the ingredients of any medication you take for anything you may be allergic to. You should not take Alvesco if you are allergic to it or any of its ingredients.
Make sure your doctor is aware of any medical conditions or allergies you have as this may impact whether or not they recommend Alvesco for you.
You should not use Alvesco if:
- you are experiencing an asthma attack or are suddenly breathless
- your respiratory tract has an untreated fungal, bacterial, or tuberculosis infection
- you have moderate to severe bronchiectasis
It’s possible to develop hoarseness, an irritated throat, and candidiasis, a yeast infection also known as thrush, when using Alvesco. To help prevent this, you can gargle with water after each use of your inhaler.
You should release 3 puffs into the air if your inhaler is new or has been left unused for at least a week.
Do not submerge your inhaler or any part of it in water. You should clean the mouthpiece once a week with a dry tissue.
Bones
Using Alvesco over a long period of time can lead to a decrease in bone density and a heightened risk of osteoporosis. Your doctor should monitor the situation.
Breathing
You should use your reliever medication if you begin wheezing or find it difficult to breathe immediately after using Alvesco. If this is the case, you should stop using it and let your doctor know.
Eyes
Using Alvesco can heighten the risk of cataracts, glaucoma, and increased pressure in the eye. Your doctor should check your eyes regularly.
Children
Alvesco has not yet been established as safe or effective for children under the age of 6.
Drug Interactions
Alvesco may interact with any of the following drugs, so you should let your doctor know or seek guidance from your pharmacist if you are taking any of them.
- aldesleukin
- “azole” antifungals, such as:
- itraconazole
- ketoconazole
- voriconazole
- boceprevir
- ceritinib
- clarithromycin
- conivaptan
- deferasirox
- delavirdine
- HIV protease inhibitors, such as:
- atazanavir
- darunavir
- lopinavir
- ritonavir
- hyaluronidase
- loop diuretics, such as:
- bumetanide
- furosemide
- loxapine
- nefazodone
- nelfinavir
- nicardipine
- telaprevir
- telithromycin
- thiazide diuretics, water pills, such as:
- hydrochlorothiazide
- indapamide
- metolazone