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Apidra Vials

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Apidra Vials
Insulin Glulisine
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Product of Canada.

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Prescription Required.Product of Canada.Shipped from Canada.

What are Apidra Vials?

Apidra is a type of insulin used to help control blood sugar levels in people with diabetes. It can be used by adults and children who are at least 4 years old. 

Apidra is a fast-acting insulin that works quickly to lower blood sugar, especially around meal times. You should take Apidra within 15 minutes before eating or up to 20 minutes after starting a meal. 

Apidra is sometimes paired with a long-acting insulin to improve blood sugar management. Avoid Apidra if you have low blood sugar or are allergic to it or any of its components.

How Do Apidra Vials Work?

Apidra vials have fast-acting insulin (insulin glulisine) that swiftly reduces blood sugar levels. This insulin is produced using a safe bacterial method. Insulin glulisine differs slightly from regular human insulin due to two swapped amino acids, aiding quicker action in the body. Apidra injection promptly begins lowering blood sugar, particularly during meals, helping diabetes management.

Dosage Information and Usage

Dosage Form and Strengths of Apidra Vials

Apidra is available in 10 mL vials. These vials are designed for multiple administration methods, including subcutaneous injection, continuous subcutaneous infusion via an insulin pump, and intravenous use under medical supervision.


Checking Insulin Label and Inspecting Solution:

  • Always check the Apidra vial label to make sure it’s the right insulin before using it.
  • Look at the insulin in the vial to see if it’s clear and colorless. Don’t use it if it looks cloudy or has particles.

Subcutaneous Injection:

  • Inject Apidra under the skin within 15 minutes before eating or within 20 minutes after starting a meal.
  • Administer injections in the abdominal wall, thigh, or upper arm. Rotate injection sites to prevent skin issues.
  • Avoid injecting into areas with skin problems such as lipodystrophy.
  • Do not mix Apidra with other insulins except NPH insulin. Draw Apidra into the syringe first if mixing with NPH insulin.

Continuous Subcutaneous Infusion (Insulin Pump):

  • Use Apidra with an insulin pump following the manufacturer’s instructions.
  • Rotate infusion sites to prevent skin complications.
  • Do not dilute or mix Apidra within the pump.
  • Replace Apidra in the pump reservoir every 48 hours.
  • Have an alternative insulin delivery method available in case of pump failure.

Intravenous Administration:

  • Administer Apidra intravenously only under medical supervision.
  • Dilute Apidra in saline solution for intravenous use and closely monitor blood glucose and potassium levels.

Apidra SoloStar Pen Usage:

  • Prepare by reading the Apidra SoloStar pen instructions thoroughly.
  • Check the insulin label to ensure correct usage.
  • Attach a new needle straight onto the pen, either by push-on or screw-on method.
  • Perform a safety test to eliminate air bubbles and ensure proper functionality.
  • Select a dose of 2 units and check for insulin flow from the needle.
  • Adjust the dose in 1-unit increments, ensuring the dose window resets to “0” after the safety test.
  • Inject into the upper arm, abdomen, or thigh as instructed by your healthcare provider.
  • Dispose of needles safely in a sharps container as directed.

Adjusting Dosage:

  • Personalize the Apidra dosage based on individual needs, blood sugar levels, and treatment objectives.
  • Modify the dose with changes in diet, physical activity, concurrent medications, or health conditions to maintain optimal control.

Storage Information

Unopened Apidra Vials: Store unopened Apidra vials in a refrigerator between 36°F and 46°F (2°C and 8°C). Keep them away from light. Do not freeze Apidra vials. Discard any vials that have been frozen. If unopened vials are not refrigerated, use them within 28 days.

Opened (In-Use) Vials: After opening, Apidra vials should be used within 28 days, even if not refrigerated. If refrigeration isn’t an option, keep opened vials at room temperature (up to 77°F or 25°C) for up to 28 days. Store them away from direct heat and light.

Side Effects

Common Side Effects

  • Injection site reactions (pain, redness, or irritation)
  • Low blood sugar (hypoglycemia), with symptoms like:
    • Sudden sweating
    • Shaking (tremor)
    • Fast heartbeat
    • Hunger
    • Blurred vision
    • Dizziness
    • Tingling hands/feet
    • Headache
    • Nausea
    • Confusion
    • Drowsiness
    • Weakness
    • Trouble concentrating
    • Seizures (convulsions)

Serious but Rare Side Effects

  • Severe allergic reactions, with symptoms like:
    • Rash over the whole body
    • Shortness of breath
    • Trouble breathing
    • Fast pulse
    • Sweating
    • Feeling faint
  • Low potassium in the blood (hypokalemia), with signs like:
    • Muscle cramps
    • Weakness
    • Irregular heartbeat
  • Heart failure, especially when taking certain diabetes pills (TZDs) with Apidra, with symptoms like:
    • Shortness of breath
    • Swelling of ankles or feet
    • Sudden weight gain

Warnings and Precautions

  • Never Share Equipment: It’s important not to share Apidra vials between different people. Even if the needle is changed, sharing can spread serious infections.
  • Risk of Blood Sugar Swings: Changes in how Apidra is used—like switching insulin types or injection methods—can affect blood sugar levels. This may lead to low blood sugar (hypoglycemia) or high blood sugar (hyperglycemia). It’s important to closely monitor blood sugar when making these changes and adjust doses as advised by your doctor.
  • Low Blood Sugar (Hypoglycemia): Apidra can sometimes cause low blood sugar, which can be severe. Symptoms include sweating, shaking, fast heartbeat, and confusion. Be cautious when driving or operating machinery, as low blood sugar can affect your ability to react quickly.
  • Avoid Medication Mistakes: Always check the Apidra label before each injection to ensure you’re using the correct insulin product. Mistakes with insulin types can be dangerous.
  • Risk of Low Potassium (Hypokalemia): Apidra, like all insulins, can shift potassium levels in the body. This might lead to low potassium levels, which can cause problems like muscle cramps or irregular heartbeat. Patients at risk for potassium imbalances should be monitored closely.
  • Allergic Reactions: Some people may have severe allergic reactions to Apidra, including anaphylaxis (a serious whole-body allergic reaction). If you experience symptoms like rash, trouble breathing, or rapid pulse, seek medical help immediately and stop using Apidra.
  • Fluid Retention and Heart Concerns: Using Apidra with certain diabetes medications called thiazolidinediones (TZDs) can sometimes cause fluid retention, which may worsen heart failure. Watch for signs like swelling or sudden weight gain, and discuss any concerns with your healthcare provider.
  • Insulin Pump Issues: If you use an insulin pump and it malfunctions, it can quickly lead to high blood sugar and ketoacidosis. Learn how to manage pump failures and have a backup plan for injecting Apidra if needed.

Overdosage of Apidra Vials

Overdosing on Apidra vials can lead to hypoglycemia, where blood sugar levels drop too low. This can happen more severely if Apidra is given intravenously, causing hypokalemia. Mild hypoglycemia can often be managed by consuming oral glucose. 

Adjustments in medication dosage, meal timing, or physical activity may be necessary to prevent further drops in blood sugar. 

For more severe cases of hypoglycemia leading to unconsciousness or seizures, emergency treatments like glucagon injections or concentrated glucose through injection may be required. 

Continuous monitoring and sustained carbohydrate intake may be needed even after apparent recovery to prevent hypoglycemia from recurring. Additionally, hypokalemia should be corrected promptly and appropriately to avoid complications.

Drug Interactions With Other Medications

When using Apidra vials, be aware of potential drug interactions. Some medications, like antidiabetic drugs, ACE inhibitors, and certain antidepressants, can increase the risk of low blood sugar (hypoglycemia).

Others, such as corticosteroids and some birth control pills, can reduce Apidra’s effectiveness, making it harder to lower blood sugar.

There are also drugs, including alcohol and beta-blockers, that can either increase or decrease Apidra’s blood sugar-lowering effects. Also, some medications might hide hypoglycemia symptoms, making them harder to recognize.

In all cases, you may need to adjust the Apidra dose and monitor blood sugar more frequently to manage these interactions effectively.

Price & Coupons

Your health is important, and the cost of essential medication like insulin should never be a barrier. In the United States, Apidra vials cost about $197 for 1 vial.

Pharma Giant is dedicated to making healthcare both accessible and affordable. We understand the importance of maintaining your health without breaking the bank, which is why we offer quality medications at reasonable prices.

Competitive Pricing Options:

QuantityPrice (USD)Percentage Discount
1 vial$60.00
2 vials$100.0016.7%
3 vials$135.0025%
4 vials$160.0033.3%

By choosing Pharma Giant, you can manage your diabetes effectively and affordably.

Exclusive Savings on Your Medication

Pharma Giant is excited to help you reduce your medication expenses with an exclusive offer.

Use the code FIRST10 at checkout and enjoy a 10% discount on your purchase of Apidra Vials.

This special offer ensures that you receive high-quality healthcare products at an affordable price.

This limited-time offer is available for one-time use per customer. Take advantage of this incredible opportunity and experience the unmatched value that Pharma Giant provides.

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Commitment to Quality and Prompt Delivery

At Pharma Giant, we prioritize delivering premium medications swiftly and reliably right to your doorstep. With our express shipping service, you can anticipate receiving your order within 3-5 business days across the United States.


Yes, Apidra can be used in the Omnipod 5. The Omnipod 5 is designed to work with rapid-acting U-100 insulin, and Apidra is one of the insulin analogs tested and found to be safe for use with this system.

The generic name for Apidra is insulin glulisine.

Apidra 100mg is a fast-acting insulin used to control high blood sugar in adults and children with diabetes mellitus. It helps manage blood sugar levels after meals.

The amount of Apidra you need depends on your specific needs. Usually, the daily insulin requirement ranges from 0.5 to 1 unit per kilogram of body weight. It’s crucial to monitor your blood sugar regularly to find the correct dosage for you.

Apidra is generally considered safe to use during pregnancy. However, it’s important to consult your doctor before using this insulin to ensure it is the best option for you. The FDA has reviewed sufficient human data and considers Apidra to be low-risk in pregnancy.

Administer Apidra via subcutaneous injection in the abdomen, thigh, or upper arm. Rotate injection sites to prevent skin issues.

Apidra (insulin glulisine) and NovoRapid (insulin aspart) are both rapid-acting insulins used to manage blood sugar levels in people with diabetes. While they serve the same purpose, they are different types of insulin with distinct chemical structures. Apidra is made from insulin glulisine, whereas NovoRapid is made from insulin aspart. They are administered similarly, either by injection under the skin using a vial or pre-filled pen, or through an insulin pump. However, they are not the same insulin and may have slightly different onset times and durations of action.

No, Apidra does not need to be refrigerated before it is opened. Once opened, however, Apidra vials should be stored in a refrigerator or at cool room temperature and used within 28 days to maintain their effectiveness. Injection pens should be stored at cool room temperature and also used within 28 days after first use, without refrigeration. 

Yes, you can take Apidra within 15 minutes before or within 20 minutes after starting a meal. This timing helps Apidra to manage your blood sugar effectively during mealtime.

Apidra comes in concentrations ranging from 0.05 unit/mL to 1 unit/mL when diluted for use in infusion systems with PVC infusion bags.