Buy Brisdelle from Canada | paroxetine

What is Brisdelle?

Brisdelle (paroxetine) is a prescription medication used to treat moderate to severe hot flashes that happen during menopause.

Hot flashes are sudden feelings of warmth, sweating, and a red face or neck. Brisdelle is the only non-hormonal medication approved by the FDA to help with this problem. 

It contains a low dose of paroxetine, which is usually used to treat depression, but in Brisdelle, it is used only for hot flashes.

Do not take Brisdelle if you are also taking certain drugs called MAOIs (Monoamine Oxidase Inhibitors), thioridazine, or pimozide.

These combinations can lead to serious health problems like heart rhythm issues or a life-threatening condition called serotonin syndrome. Also, avoid Brisdelle if you are pregnant, allergic to paroxetine, or taking other medications with paroxetine.

Always tell your doctor about all your medical conditions and any drugs or supplements you take before starting Brisdelle.

How Does Brisdelle Work?

Brisdelle helps balance a natural chemical in your brain called serotonin.

Although Brisdelle is usually used as an antidepressant in higher doses, this version uses a very low dose of paroxetine. It is the only non-hormonal prescription drug approved to treat hot flashes.

Even though doctors are not exactly sure how it helps with menopause symptoms, many people start feeling better after about 30 to 90 days. If you do not see any improvement after three months, talk to your doctor about other options.

Brisdelle Dose and Administration

Brisdelle comes as a capsule that you swallow. It is available in a single strength of 7.5 milligrams. You take it once each day, usually at bedtime. 

This helps reduce hot flashes during the night. You can take Brisdelle with or without food, but you should always follow your doctor’s directions.

Dosage Form and Strengths of Brisdelle

Brisdelle is available as an oral capsule. Each capsule contains 7.5 milligrams of paroxetine mesylate.

This is the only dose approved for the treatment of moderate to severe hot flashes related to menopause. Unless your doctor advises otherwise, you do not need to change the Brisdelle dose over time. Never crush, split, or chew the capsule.

How to Take Brisdelle?

• Swallow one 7.5 mg capsule whole every night before bed.
• Take it at the same time each day to help maintain a routine.
• You may take Brisdelle with or without food.
• Do not crush, chew, or open the capsule.
• If you miss a dose, skip it and take the next one at your regular time. Do not take two doses.

Brisdelle Side Effects

Some common Brisdelle side effects include headache, tiredness, and nausea. In rare cases, serious problems like vision changes, seizures, or suicidal thoughts can happen. It is important to know both the mild and severe side effects of Brisdelle before starting this treatment.

Common Side Effects

These are some of the most reported side effects of Brisdelle medication:

• Headache
• Tiredness or low energy
• Nausea
• Vomiting
• Sleep problems
• Sweating
• Dizziness
• Constipation
• Dry mouth
• Weakness

These side effects of Brisdelle are usually mild and may go away on their own after a few days or weeks.

Severe Side Effects

While not common, serious Brisdelle side effects may include:

• Suicidal thoughts or behavior
• Seizures
• Hallucinations (seeing or hearing things that are not real)
• Agitation or confusion
• Mood changes or mania
• Trouble concentrating
• Bone fractures or pain
• Serious allergic reactions (swelling, difficulty breathing)
• Unusual bleeding or bruising
• Eye pain or vision changes
• Very low sodium levels (can cause headache, confusion, or fainting)
• Sexual problems (low desire or trouble with orgasm)

If you notice any serious side effects of Brisdelle, contact a doctor immediately or call emergency services if the symptoms feel life-threatening.

Warnings and Precautions for Brisdelle

Brisdelle is a medication used to treat moderate to severe hot flashes linked to menopause. Although helpful, it may cause serious side effects in some people.

It is important to know the warnings and precautions before using Brisdelle to ensure its safety.

• Brisdelle increases the risk of suicidal thoughts and behaviors, especially in young adults. Monitor patients closely for mood or behavior changes.
• Brisdelle can cause serotonin syndrome, a serious condition that can happen when used alone or with other drugs that affect serotonin. Symptoms include confusion, sweating, shaking, or stomach upset.
• Do not take Brisdelle using MAO inhibitors like linezolid or intravenous methylene blue. Wait at least 14 days after stopping one before starting the other.
• Taking Brisdelle with thioridazine or pimozide can increase the risk of serious heart rhythm problems.
• Brisdelle may lower how well tamoxifen works for breast cancer. If you take tamoxifen, talk to your doctor about other treatment options.
• Brisdelle may raise the risk of bleeding, especially if taken with blood thinners or NSAIDs. Watch for signs of unusual bruising or bleeding.
• Brisdelle can cause angle-closure glaucoma in people with narrow eye angles. Tell your doctor if you have eye problems before using it.
• Brisdelle may lead to low sodium levels in the blood, especially in older adults or those on water pills. Symptoms include confusion, weakness, and falls.
• People taking Brisdelle may have a higher chance of bone fractures. Report any unexplained bone pain or swelling.
• Brisdelle should not be used to treat depression or bipolar disorder. Patients should be screened for bipolar disorder before starting Brisdelle.
• Brisdelle may increase the risk of seizures. If you have had seizures before, use it with caution and stop it if you have a seizure.
• Brisdelle may cause sexual problems like low desire or delayed orgasm. Patients should talk to their doctor if they notice changes in sexual function.

Brisdelle Drug Interactions

If you are taking Brisdelle, it is important to know that this medication can interact with other drugs and supplements.

These interactions might make Brisdelle less effective or increase the chance of side effects. 

Always tell your doctor and pharmacist about everything you take, even over-the-counter medications and herbal products.

Below is a list of known drug interactions with Brisdelle.

• Zoloft (sertraline)
• Lexapro (escitalopram)
• Prozac (fluoxetine)
• Cymbalta (duloxetine)
• Effexor XR (venlafaxine)
• imipramine
• amitriptyline
• Norpramin (desipramine)
• Lithobid (lithium)
• Actiq (fentanyl)
• Fentora (fentanyl)
• Ultram (tramadol)
• buspirone
• Adderall XR (amphetamine/dextroamphetamine)
• Dexedrine (dextroamphetamine)
• Vyvanse (lisdexamfetamine)
• Nardil (phenelzine)
• selegiline
• Advil (ibuprofen)
• Motrin (ibuprofen)
• Aleve (naproxen)
• aspirin
• warfarin
• tamoxifen
• Lanoxin (digoxin)
• Risperdal (risperidone)
• Theo-24 (theophylline)
• thioridazine
• pimozide
• St. John’s wort

Alternative Medications to Brisdelle

If Brisdelle is not working well for your hot flashes or causing side effects, other medications might help. These can include both hormone and non-hormone options. Talk to your doctor to find the treatment that is best for you.

• Effexor XR (venlafaxine)
• Celexa (citalopram)
• Gralise (gabapentin)
• Neurontin (gabapentin)
• Lyrica (pregabalin)
• Catapres (clonidine)
• Activella (estradiol/norethindrone)
• Amabelz (estradiol/norethindrone)
• Angeliq (estradiol/drospirenone)
• Climara Pro (estradiol/levonorgestrel)
• Fyavolv (ethinyl estradiol/norethindrone)
• Jinteli (ethinyl estradiol/norethindrone)
• Duavee (estrogen/bazedoxifene)
• Prempro (estrogen/medroxyprogesterone)
• Premphase (estrogen/medroxyprogesterone)
• Covaryx (estrogen/methyltestosterone)
• Menest (oral estrogen)
• Premarin (oral estrogen)
• Estropipate
• Oral estradiol
• Climara (estradiol patch)
• Minivelle (estradiol patch)
• Vivelle-Dot (estradiol patch)
• Divigel (estradiol topical gel)
• Elestrin (estradiol topical gel)
• EstroGel (estradiol topical gel)
• Evamist (estradiol topical spray)
• Depo-Estradiol (estradiol injection)
• Delestrogen (estradiol injection)
• Femring (estradiol vaginal ring)
• Lyrica (pregabalin)

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Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.