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Caverject Alprostadil
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What is Caverject?

Caverject (alprostadil) is a prescription medicine used to treat erectile dysfunction (ED), which is the inability to get or keep an erection firm enough for sexual activity. 

It contains alprostadil, a natural substance that helps improve blood flow to the penis. This medication is injected directly into the penis to help achieve an erection. 

Caverject is also used in some medical tests to diagnose the cause of ED. It is not intended for use by women or children. 

Before using Caverject, it’s important to inform your healthcare provider about your medical history and any other medicines you’re taking to avoid potential interactions.

How Does Caverject Work?

Caverject works by using alprostadil, a substance that helps relax the blood vessels in the penis. 

When injected, alprostadil causes the smooth muscles in the penis to relax and the blood vessels to widen.

This allows more blood to flow into the penis, leading to an erection. It also helps trap the blood by compressing the veins, which maintains the erection. 

Caverject makes it easier for the blood to fill and stay in the penis, which helps achieve and maintain an erection.

Dosage Information and Usage

Dosage Form and Strengths of Caverject

  • Available in single-dose vials.
  • Strengths: 20 mcg/vial and 40 mcg/vial.

Usage

Initial Administration

  • Your first dose of Caverject should be administered in your healthcare provider’s office. This allows for monitoring and instruction on the proper use of the medication.
  • Your doctor will demonstrate the injection technique, including how to prepare the medication and administer the injection. Pay close attention and ask any questions to ensure you understand the process.

Preparation

  • Collect all necessary supplies, including Caverject vial, syringe, and needle. Ensure your hands and the surface where you are working are clean.
  • Check that the Caverject vial has not expired and the solution is clear. Do not use if it is discolored or contains particles.
  • Draw Medication:
    • Clean the top of the Caverject vial with an alcohol swab.
    • Attach the needle to the syringe and draw the prescribed amount of Caverject into the syringe.
    • Remove any air bubbles by tapping the syringe and pushing the plunger slightly.

Injection Site

  • Choose an injection site on the side of the penis, preferably where there are fewer veins or prominent structures. Rotate sites with each use to prevent tissue damage.
  • Use an alcohol swab to clean the area where you will inject. Allow the area to dry before injecting.

Administering the Injection

  • Insert the needle at a 90-degree angle into the cleaned area of the penis.
  • Slowly push the plunger to inject the medication. Avoid injecting too quickly as this can cause discomfort.
  • Once the medication is fully injected, withdraw the needle gently and apply slight pressure with a clean cotton swab or gauze to the injection site to minimize bleeding.

Post-Injection

  • Dispose of the used needle and syringe in a puncture-resistant sharps container immediately. Do not throw them in regular trash.
  • Monitor the injection site for any adverse reactions such as prolonged pain, swelling, or redness.

Frequency of Use

  • Use Caverject no more than 3 times per week. Ensure there is at least a 24-hour gap between injections.
  • Keep a log of your injections to help manage the frequency and avoid overuse.

Storage Information

Store Caverject vials in a cool, dry place. For 20 mcg vials, keep them between 68°F and 77°F (20°C to 25°C). 

Use the reconstituted solution within 24 hours, and do not refrigerate or freeze it. For 40 mcg vials, store them between 36°F and 46°F (2°C to 8°C) until ready to use. 

After dispensing, these vials can be stored at or below 77°F (25°C) for up to 3 months or until the expiration date. 

Use the reconstituted solution within 24 hours and do not refrigerate or freeze it. 

Always use bacteriostatic water for injection to reconstitute Caverject.

Side Effects

Common Side Effects

  • Penile pain

Serious but Rare Side Effects

  • Priapism  (erection lasting over 4 hours)
  • Penile Fibrosis (change in penis shape)
  • Low blood pressure
  • Injection site bleeding
  • Heart problems (symptoms like chest pain, dizziness, or nausea)

Warnings and Precautions

  • Prolonged Erection and Priapism: An erection lasting longer than 4 hours requires immediate medical help. Prolonged erections or priapism (lasting more than 6 hours) can cause permanent damage if not treated right away. To reduce the risk, use the lowest effective dose and avoid Caverject if you have conditions that increase the risk of priapism, like sickle cell anemia or leukemia.
  • Penile Fibrosis: Periodic checks of the penis are needed to spot any signs of fibrosis, a condition where the tissue hardens. If you develop penile angulation or fibrosis, stop using Caverject. The incidence of penile fibrosis in clinical studies was about 3%, and up to 7.8% in long-term studies.
  • Hypotension: Using Caverject can lead to low blood pressure. Avoid using it if you have cavernosal venous leakage. Monitor for signs of hypotension and consult your doctor if you have concerns.
  • Injection Site Bleeding When Used with Anticoagulants: If you’re on blood thinners like warfarin or heparin, you may experience increased bleeding at the injection site. Apply pressure with an alcohol swab or sterile gauze for 5 minutes to minimize bleeding.
  • Cardiovascular Risk Related to Underlying Medical Conditions: Sexual activity can pose cardiac risks for those with heart conditions. Only use Caverject if your heart is healthy enough for sexual activity. A full medical assessment should determine if it’s safe for you.
  • Risks of Use in Combination with Other Vasoactive Medications: Combining Caverject with other vasoactive drugs may increase the risk of prolonged erection, priapism, and low blood pressure. The safety of such combinations has not been well-studied.
  • Needle Breakage: Use separate needles for reconstitution and injection. Superfine needles used for Caverject can break and may require medical intervention if a piece is left in the penis. Follow proper handling and injection techniques to avoid breakage.
  • Risk of Serious Adverse Reactions in Infants due to Benzyl Alcohol Preservative: Caverject contains benzyl alcohol, which can cause serious reactions, including “gasping syndrome,” in infants. This drug is not intended for children.
  • Counsel Patients about Sexually Transmitted Diseases: Caverject does not protect against sexually transmitted infections, including HIV. Use appropriate protective measures to prevent transmission of diseases.

Overdosage of Caverject

Overdosage of Caverject was not seen in clinical trials. If too much of the drug is injected into the penis, you should seek medical help immediately. 

Doctors will monitor you until the effects, such as prolonged erection or low blood pressure, are resolved. It is important to address any symptoms or side effects promptly with appropriate treatment.

Drug Interactions With Other Medications

The potential for interactions between alprostadil and other medications has not been extensively studied.

Alternative Medications

Cost & Coupons

At Pharma Giant, we believe your health should come first, and getting the right medication shouldn’t break the bank.

Our goal is to make sure that high-quality medications like Caverject are priced fairly, making healthcare accessible for everyone.

You can buy Caverject in 20ug – 5 injections for just $264.50 at PharmaGiant.com. This price is much lower than the usual U.S. cost, which can cost over $600.

Special Discount Offer

  • Coupon Code: Enter PGSAVE10 at checkout to get a 10% discount on your Caverject order. This exclusive offer is only for a limited time, so make sure to use it and save on important medications without losing quality.
  • Offer Details: The discount can be used one time only per customer, so take advantage of this while it’s available.

How to Order

  • Prescription Needed: You can only buy Caverject with a valid prescription to make sure it’s safe for you and follows medical guidelines.
  • Larger Orders: Patients can order up to a 90-day supply, making it easier to manage ongoing treatment and costs.

Quality Assurance and Quick Delivery

At Pharma Giant, we promise to provide high-quality medication with the added benefit of fast delivery right to your home.

  • Fast Shipping: Medications are shipped quickly from Canada to anywhere in the US in 3-5 business days, so you’ll get your order on time.
  • Safe Packaging: Every order is packed securely in tamper-proof containers, ensuring your medication stays safe and perfect during delivery.

Why Choose Pharma Giant?

With Pharma Giant, you can care for your health without the worry of high costs. Experience great value and excellent service today!

Frequently Asked Questions

Caverject is used to treat erectile dysfunction by helping achieve and maintain an erection.

To administer Caverject, follow these steps:
  • Prepare the injection: Reconstitute the Caverject powder with bacteriostatic water as directed.
  • Draw up the solution: Use a syringe to draw the reconstituted solution.
  • Inject the medication: Insert the needle into the base of the penis and inject the solution.
  • Dispose of supplies: Safely discard used needles and syringes.
Always follow your healthcare provider’s instructions for the correct dosage and technique.

The recommended dosage of Caverject varies based on individual needs and responses. Typically, treatment starts with a low dose, and adjustments are made as needed. The usual starting dose is 2.5 to 5 micrograms, which may be increased up to a maximum of 60 micrograms based on effectiveness and tolerability.

To prepare Caverject for injection, start by adding 1 mL of bacteriostatic water to the vial containing the Caverject powder. Gently swirl the vial until the powder is fully dissolved; avoid shaking the vial. Once the solution is clear, use a syringe to draw the required amount of the reconstituted solution from the vial. Follow your healthcare provider’s instructions for administering the injection.

Caverject typically works within 5 to 20 minutes to produce an erection that lasts about 1 hour. It is recommended to use Caverject no more than 3 times a week, with at least 1 day between each dose.

If you miss a dose of Caverject, there’s no need to worry. This medication is used only when needed, so simply take it as directed by your doctor when you require it. Do not use it more often than your doctor has prescribed.

If you have heart problems, you should be cautious about using Caverject. Sexual activity can put extra strain on your heart, so this medication might not be safe if your heart condition makes sexual activity risky.

Common side effects of Caverject include penile pain, bruising at the injection site, mild bleeding at the injection site, and dizziness.

If you experience a prolonged erection lasting more than 4 hours after using Caverject, seek immediate medical attention. A prolonged erection, known as priapism, can cause permanent damage to your penis if not treated promptly.

Yes, Caverject can cause serious side effects. These include a prolonged erection (priapism), penile fibrosis (a condition where the tissue inside the penis becomes scarred), low blood pressure, and an increased risk of heart problems during sexual activity. Injection site bleeding and the potential for needle breakage are also serious concerns.

You should be cautious when using Caverject with other medications. The potential for drug interactions with Caverject has not been thoroughly studied, so it’s important to talk to your healthcare provider about any medications you’re taking before using Caverject.

While using Caverject, avoid angling the syringe and do not bend the needle to prevent breakage. Also, avoid injecting into visible veins. Make sure to alternate the side of the penis with each injection to prevent complications. After injecting, press the injection site with an alcohol swab or sterile gauze for 5 minutes to minimize bleeding.

Store Caverject vials at room temperature between 20°C to 25°C (68°F to 77°F). Once the solution is mixed, use it within 24 hours and keep it at or below 25°C (77°F). Do not refrigerate or freeze the reconstituted solution.

The safety and effectiveness of using Caverject in combination with other erectile dysfunction treatments that are also injected into the penis have not been established.

If you notice any changes in your penis after using Caverject, stop using the medication and consult your doctor immediately.

Caverject typically works within 5 to 20 minutes, producing an erection that lasts about 1 hour. It should not be used more than 3 times a week, with at least 1 day between doses.

If you have a history of bleeding disorders, consult your healthcare provider before using Caverject.

Caverject should not be used more than 3 times a week, with at least 1 day between each dose.

After your injection, dispose of used Caverject syringes and needles in an FDA-cleared sharps disposal container immediately.

It’s best to avoid consuming alcohol while using Caverject. Alcohol can interfere with the effectiveness of erectile dysfunction (ED) medications.

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

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