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What is Diamicron?

Diamicron (gliclazide) is a medication used to help manage blood sugar levels in people with type 2 diabetes. 

It contains gliclazide, a second-generation sulfonylurea oral hypoglycemic agent.. Diamicron works by increasing the amount of insulin released from the pancreas and helping the body use insulin more effectively. 

It’s typically used when diet, exercise, and weight loss alone aren’t enough to control blood sugar levels. 

Diamicron may be available under different brand names and in various forms, but not all forms may be suitable for every condition. 

Always use this medication as prescribed by your doctor, and don’t stop taking it or share it with others without consulting your doctor.

How Does Diamicron Work?

Diamicron helps lower blood sugar levels by boosting the amount of insulin your pancreas produces. 

Insulin is a hormone that helps control blood glucose. By increasing insulin levels, Diamicron helps your body use glucose more effectively. It’s used when diet and exercise alone aren’t enough to manage blood sugar. 

However, like other diabetes medications, Diamicron can sometimes cause blood sugar levels to drop too low, a condition called hypoglycemia. 

Keeping blood sugar levels well-managed is important to avoid long-term health problems, such as issues with the heart, kidneys, or eyes.

Dosage Information and Usage

Dosage Form and Strengths of Diamicron

  • Diamicron: 80 mg, standard tablets

Diamicron MR (modified-release) tablets contain 30 mg or 60 mg of gliclazide for once-daily dosing.

Usage

  • Recommended Dosage: Immediate-release gliclazide is typically prescribed in doses of 40 mg to 320 mg daily, divided into one or two doses.
  • Maximum Dose: The daily dose should not exceed 320 mg.

Dosage Adjustments:

  • Factors Influencing Dose: Body weight, other medical conditions, and concurrent medications can affect your dosage. Always follow your doctor’s specific recommendations.
  • Missed Dose: If you miss a dose, take it as soon as you remember, but skip it if it’s close to your next dose. Do not double up on doses. Consult your doctor or pharmacist if you’re unsure about what to do.

Storage Information

To ensure the effectiveness and safety of Diamicron, store the medication at room temperature, away from light and moisture, and keep it out of reach of children. 

When it comes to disposing of the medication, do not throw it away in wastewater or household garbage. 

Instead, consult your pharmacist for advice on how to properly dispose of expired or unused medication.

Side Effects

Common Side Effects

  • Abdominal pain
  • Back, muscle, or joint pain
  • Constipation
  • Diarrhea
  • Dizziness
  • Headache
  • Heartburn
  • Increased skin sensitivity to the sun
  • Nausea
  • Vomiting

Serious but Rare Side Effects

  • Skin rash or hives
  • Signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or eyes, dark urine, pale stools)
  • Swelling of the legs
  • Symptoms of low blood sugar (e.g., anxiousness, blurred vision, cold sweats, confusion, difficulty concentrating, drowsiness, fast heart rate, headache, hunger, nervousness, nightmares, shakiness, slurred speech, unusual tiredness, unexpected weight gain)
  • Chest pain or pressure and/or shortness of breath
  • Seizures
  • Signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, swelling of the face and throat)
  • Severe skin reactions (e.g., blistering, peeling, widespread rash, rash with fever or joint pain)
  • Unconsciousness

Warnings and Precautions

  • Alcohol Use: Gliclazide can cause unpleasant reactions with alcohol, including flushing, nausea, and increased heart rate. To avoid these symptoms, it is best to avoid drinking alcohol while taking this medication.
  • Anemia: If you have glucose-6-phosphate dehydrogenase (G6PD) deficiency, gliclazide might lead to hemolytic anemia, where red blood cells break down abnormally. Discuss with your doctor how gliclazide might impact your condition and if any special monitoring is needed.
  • Diabetes Complications: Gliclazide will not prevent diabetes-related complications, even though it helps control blood sugar levels. Continue to manage diabetes through diet and lifestyle changes to avoid long-term issues.
  • Driving and Operating Machinery: Gliclazide can cause low blood sugar, leading to dizziness or reduced alertness. Avoid tasks like driving until you know how this medication affects you.
  • Hypoglycemia (Low Blood Sugar): Gliclazide can cause symptoms of low blood sugar such as dizziness, headache, and sweating. Regularly monitor your blood glucose and keep emergency glucose on hand to manage these symptoms.
  • Illness/Stress: Illness or stress may affect blood sugar control and might require temporary use of insulin. Consult your doctor if you experience significant changes in your blood sugar during stressful situations.
  • Kidney Function: Reduced kidney function can cause gliclazide to accumulate, leading to side effects. If you have kidney problems, discuss with your doctor how this medication may impact you and if special monitoring is needed.
  • Liver Function: Liver issues may lead to an accumulation of gliclazide in your body, causing side effects. Regular liver function tests may be necessary if you have liver problems.
  • Porphyria: Gliclazide can trigger attacks of acute porphyria, a rare blood disorder. If you have porphyria, discuss the risks and any necessary monitoring with your doctor.
  • Proper Diet: Gliclazide should be used in conjunction with a proper diet, not as a replacement for it. Follow dietary recommendations to effectively manage your blood sugar.
  • Worsening of Condition: Over time, gliclazide might become less effective as diabetes progresses. If your blood sugar is not well-controlled, talk to your doctor about adjusting your treatment.
  • Pregnancy: Gliclazide may harm an unborn baby. If you become pregnant, contact your doctor immediately to discuss alternative treatments.
  • Breastfeeding: It’s unclear if gliclazide passes into breast milk. If you are breastfeeding, consult your doctor to determine if you should continue with this medication.
  • Children: The safety and effectiveness of gliclazide in children have not been established. This medication is not recommended for use in children.
  • Seniors: Older adults may be more sensitive to the side effects of gliclazide, especially low blood sugar. Monitor for symptoms and discuss any concerns with your doctor.

Overdosage

If you take too much Diamicron, you should contact your doctor or go to the nearest hospital right away. 

Symptoms of an overdose can include severe low blood sugar, which can be treated by eating 4-6 pieces of sugar or drinking sugar water immediately, followed by eating other foods. 

If someone who has taken an overdose is unconscious, call an ambulance and inform the medical professionals as soon as possible.

Drug Interactions With Other Medications

  • Miconazole (systemic route, oromucosal gel): This medication can increase the hypoglycemic effect of Diamicron, potentially leading to severe low blood sugar or even coma. Avoid using miconazole with Diamicron and closely monitor blood glucose levels if used together.
  • Phenylbutazone (systemic route): This drug can enhance the hypoglycemic effect of Diamicron by affecting how the medication binds to plasma proteins or is eliminated from the body. Consider alternative anti-inflammatory agents or carefully monitor blood glucose levels and adjust Diamicron dosage if necessary.
  • Alcohol: Consuming alcohol can worsen the hypoglycemic effects of Diamicron, increasing the risk of severe low blood sugar. It’s best to avoid alcohol and products containing alcohol to prevent dangerous drops in blood glucose levels.
  • Other Antidiabetic Agents (insulin, acarbose, metformin, thiazolidinediones, GLP-1 receptor agonists): Combining Diamicron with these agents may intensify the blood glucose-lowering effects, increasing the risk of hypoglycemia. Monitor blood glucose levels closely and adjust doses as needed.
  • Beta-Blockers, Fluconazole, ACE Inhibitors (e.g., captopril, enalapril), H2-Receptor Antagonists, MAOIs, Sulfonamides, Clarithromycin, NSAIDs: These medications may enhance the blood glucose-lowering effect of Diamicron, raising the risk of low blood sugar. Monitor your blood glucose levels more frequently and consult your doctor about potential dose adjustments.
  • Danazol: Danazol can raise blood glucose levels, making diabetes harder to control. If you need to use danazol, monitor blood glucose closely and adjust the Diamicron dose as needed.
  • Chlorpromazine (neuroleptic agent): High doses of chlorpromazine can increase blood glucose levels by reducing insulin release. Monitor your blood glucose levels and adjust the Diamicron dosage if necessary.
  • Glucocorticoids (systemic and local routes) and Tetracosactide: These substances can increase blood glucose levels and reduce carbohydrate tolerance. Monitor blood glucose closely and adjust the Diamicron dose during and after treatment.
  • Ritodrine, Salbutamol, Terbutaline (I.V.): These beta-2 agonists can raise blood glucose levels. Regular blood glucose monitoring is essential, and insulin may be needed if blood sugar levels increase significantly.
  • Saint John’s Wort (Hypericum perforatum): This herbal product can decrease the effectiveness of Diamicron. Monitor blood glucose levels closely and consider dose adjustments if needed.
  • Fluoroquinolones: When used with Diamicron, these antibiotics can cause changes in blood glucose levels. It’s important to monitor blood glucose levels regularly to avoid potential dysglycemia.
  • Anticoagulants (e.g., warfarin): Diamicron can enhance the effects of anticoagulants, increasing bleeding risk. Regular blood tests are needed to monitor and adjust anticoagulant dosage as necessary.

Alternative Medications

Cost & Coupons

At Pharma Giant, we know your health is important, and getting the right medicine shouldn’t cost too much. We aim to ensure that high-quality medications, including Diamicron, are affordable for everyone.

Diamicron is a medicine used to help people with diabetes control their blood sugar levels. Pharma Giant is committed to providing a wide range of essential medications at competitive prices. Our goal is to support your health by offering trusted medication and excellent service.

Great Deals on Diamicron

Your health matters, and getting the right medicine shouldn’t be costly. That’s why Pharma Giant is here, committed to making healthcare affordable and easy to access.

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Brand-Name Diamicron Pricing:

Strength Quantity Price (Canada) Price per Tablet
80mg 60 tabs $59.95 $1.00
120 tabs $114.00 $0.95
180 tabs $165.00 $0.92

Generic Gliclazide (Equivalent to Diamicron) Pricing:

Strength Quantity Price (Canada) Price per Tablet
80mg 60 tabs $31.95 $0.53
120 tabs $57.95 $0.48
180 tabs $82.95 $0.46

We offer quality medications at fair prices. Don’t let money issues get in the way of your health. Choose Pharma Giant and take care of your health without spending too much!

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Offer Details: The discount is available for one-time use per customer, so make sure to use it while it’s still available.

How to Order

  • Need a Prescription: You must have a valid prescription to buy Diamicron. This ensures safety and follows medical guidelines.
  • Order in Bulk: You can order up to a 90-day supply at once, making it easier to manage your treatment and reduce costs.

Quality and Quick Delivery

At Pharma Giant, we focus on providing high-quality medication with the added benefit of fast delivery straight to your home.

  • Fast Shipping: We ship medications from Canada to anywhere in the US within 3-5 business days. This makes sure you get your order quickly.
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With Pharma Giant, you can look after your health without worrying about high costs. Our extensive range of affordable medications and healthcare services ensures that you receive great value and excellent care.

Frequently Asked Questions

Diamicron is prescribed to help manage blood sugar levels in people with type 2 diabetes. It works by increasing insulin production from the pancreas to lower blood glucose levels.
The best time to take Diamicron is with breakfast each day. Consistency in timing helps manage blood sugar levels and reduces the risk of low blood sugar.
Diamicron is contraindicated in the following cases:
  • Hypersensitivity to gliclazide or any of its components.
  • Type 1 diabetes, diabetic pre-coma, coma, or diabetic keto-acidosis.
  • Severe hepatic or renal insufficiency, where insulin is preferred.
Diamicron works by stimulating insulin secretion from the ?-cells in the pancreas, which helps lower blood glucose levels. It also has beneficial effects on blood vessels and circulation.
Store Diamicron at room temperature, away from light and moisture. Keep it out of reach of children.
If you miss a dose of Diamicron, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Diamicron should generally be avoided during pregnancy as it may affect your developing baby. Insulin is typically preferred for controlling blood glucose levels during pregnancy. Your doctor will likely switch you to insulin if you become pregnant.
Diamicron is not recommended while breastfeeding, as it is not known whether it passes into breast milk. If you are breastfeeding, discuss with your doctor about alternative treatments.
Common side effects of Diamicron include abdominal pain, back, muscle, or joint pain, and gastrointestinal issues such as constipation and diarrhea. Some people may experience dizziness, headache, or heartburn. Additionally, increased skin sensitivity to the sun, nausea, and vomiting can occur.
Serious side effects of Diamicron include skin rash or hives, signs of liver problems such as yellowing of the skin or eyes, dark urine, and loss of appetite. Swelling of the legs and symptoms of severe low blood sugar like confusion, blurred vision, and unusual tiredness are also significant. If you experience any of these serious side effects, seek medical attention immediately.
Diamicron can interact with other medications, which may affect its effectiveness or increase the risk of side effects. It is essential to inform your doctor about all the medications you are taking, including over-the-counter drugs and supplements. Your doctor can guide you on how to use Diamicron safely with other medications.
Diamicron can interact negatively with alcohol, increasing the risk of hypoglycemia (low blood sugar). Drinking alcohol while taking Diamicron may cause symptoms like flushing, nausea, dizziness, and an increased heart rate. It is best to avoid alcohol or consult your doctor about safe consumption if you are taking Diamicron.
If you overdose on Diamicron, seek medical attention immediately. Symptoms of an overdose may include severe hypoglycemia (low blood sugar), which can be treated by consuming sugar or drinking sugary liquids. If you are unconscious, call emergency services right away.
Diamicron 80 mg is not recommended for use in children. If you or your child have any intolerance to sugars like glucose, lactose, or galactose, consult your doctor before using this medication.
Diamicron can affect kidney function, as kidney disease or reduced kidney function may cause the medication to accumulate in the body, leading to potential side effects. If you have impaired kidney function, consult your doctor to discuss how this medication may impact your condition and whether any adjustments or monitoring are needed.
While taking Diamicron, you should avoid alcohol. The medication can cause an unpleasant reaction when combined with alcohol, leading to symptoms such as flushing, warmth, nausea, dizziness, and possibly an increased heart rate. To prevent these effects, it is best to refrain from drinking alcohol.

Diamicron typically starts to work within 6 hours.
Yes, Diamicron can cause low blood sugar (hypoglycemia). Symptoms may include dizziness, lack of energy, drowsiness, headache, and sweating. Other signs can be weakness, nervousness, shakiness, and numbness or tingling.
Yes, there may be a need for regular liver function tests while on Diamicron. Your doctor might schedule these tests to monitor your liver health during treatment.
Yes, Diamicron can cause weight gain. Weight gain is a possible side effect, along with hypoglycemia, which is a more serious side effect of this medication.

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

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Price Match Guarantee

We are committed to providing fair, competitive pricing on all medications. If you find a lower price on the same product at another verified Canadian online pharmacy, we’ll match it.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online pharmacy with a verifiable address.
  • The competitor’s price must be current and active (not from a past or future promotion).
  • The product must be identical in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be submitted before placing an order — adjustments cannot be made after purchase.
  • Price matching does not apply to used or expired products.
  • Requests can be submitted via live chat or phone prior to completing your order.

Note: Price matching does not currently apply to Mounjaro® , Ozempic® or Saxenda®. However, this policy may be updated in the future.

Kenneth Fill, PharmD, MBA Fill

Kenneth Fill, PharmD, MBA, is a clinical pharmacist specialist and medical writer with a strong background in ambulatory care, pharmacogenomics, and medical content development. Based in the state of Michigan, he provides expert guidance on chronic disease state management. Kenneth completed his PharmD and MBA at the University of Toledo and pursued post-graduate residency training in ambulatory care and community-based pharmacy. His diverse background also includes academic detailing, clinical education, and interdisciplinary collaboration to enhance patient outcomes.