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Dymista Azelastine Hydrochloride, Fluticasone Propionate
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What is Dymista?

Dymista (azelastine hydrochloride, fluticasone propionate) is a prescription nasal spray used to relieve symptoms of seasonal allergic rhinitis in people aged 6 years and older. 

Seasonal allergic rhinitis is a condition where you experience nasal symptoms like a stuffy or runny nose, itching, and sneezing due to allergens such as pollen. Dymista helps reduce these symptoms. It is applied directly to the nose.

Before use, tell your doctor if you have recent nasal surgery, nasal ulcers, or trauma; glaucoma or cataracts; active or latent infections (including tuberculosis); or immunosuppression.

Also, inform them if you are pregnant, breastfeeding, or taking other medications, especially antifungal or anti-HIV drugs, as these can interact with Dymista.

How Does Dymista Work?

Dymista combines two medications to help relieve symptoms of seasonal allergic rhinitis, such as a runny or stuffy nose, itching, and sneezing.

These two components work in different ways:

  • Azelastine Hydrochloride: This is an antihistamine. Histamines are chemicals in your body that cause allergy symptoms like itching and sneezing. Azelastine blocks histamine from attaching to its receptors in the body, which helps to reduce these allergic reactions.
  • Fluticasone Propionate: This is a corticosteroid. Corticosteroids reduce inflammation, which is swelling and irritation in your nasal passages caused by allergies. Fluticasone works by decreasing the activity of various cells and chemicals that contribute to inflammation, helping to lessen symptoms like nasal congestion and a runny nose.

Together, these medications provide relief by tackling both the allergic reactions and the inflammation that causes your nasal symptoms.

Dosage Information and Usage

Dosage Form and Strengths of Dymista

Dymista is available as a nasal spray, with each metered spray delivering 137 mcg of azelastine hydrochloride and 50 mcg of fluticasone propionate.

This combination helps relieve allergy symptoms.

Usage

To use Dymista, follow these steps:

  • Shake the bottle gently before each use.
  • Prime the spray pump by releasing 6 sprays or until a fine mist appears before the first use or if it hasn’t been used for 14 days.
  • For each dose, spray 1 spray into each nostril twice a day.
  • Avoid spraying into your eyes. If it gets in your eyes, rinse them with water for at least 10 minutes.
  • After each use, wipe the spray tip with a clean tissue and replace the dust cap.
  • Each bottle provides enough for 120 sprays. Track your usage and discard the bottle after 120 sprays, even if there is still some medicine left.

Storage Information

To store Dymista correctly, keep the bottle upright with the dust cap on at room temperature, between 68°F to 77°F (20°C to 25°C).

Make sure to protect the bottle from light and do not store it in the freezer or refrigerator.

Check the expiration date on the bottle and discard the bottle after using 120 sprays, even if there is still some medicine left, to ensure you receive the correct dose.

Side Effects

Common Side Effects

  • Changes in taste
  • Nosebleeds
  • Headache

Serious but Rare Side Effects

  • Sleepiness or drowsiness
  • Nasal problems:
    • Crusting in the nose
    • Nosebleeds
    • Runny nose
  • Hole in the cartilage of the nose (may cause a whistling sound when breathing)
  • Slow wound healing (avoid use if you have nasal sores, recent surgery, or nasal injury)
  • Thrush (a fungal infection in the nose and throat; look out for redness or white patches)
  • Eye problems: Glaucoma or cataracts (regular eye exams are recommended)
  • Immune system issues and increased risk of infections (watch for fever, aches, chills, and fatigue)
  • Adrenal insufficiency (symptoms include tiredness, weakness, nausea, vomiting, and low blood pressure)
  • Slowed or delayed growth in children (monitor growth regularly)

Warnings and Precautions

  • Somnolence: Some patients may feel sleepy or drowsy after using Dymista. Avoid activities that require full alertness, like driving or operating machinery. Avoid using Dymista with alcohol or other central nervous system depressants as it may worsen drowsiness.
  • Local Nasal Effects: Dymista may cause nosebleeds and nasal dryness. If you have recent nasal injuries or surgery, wait until your nose is healed before using it. Monitor for infections like Candida (thrush) in your nose or throat, especially with long-term use.
  • Glaucoma and Cataracts: Using Dymista can increase the risk of eye problems such as glaucoma and cataracts. Regular eye check-ups are important if you have a history of these issues or notice vision changes.
  • Immunosuppression and Risk of Infections: Dymista can weaken your immune system, making you more prone to infections like chickenpox or measles. Be cautious around people with these infections, and seek medical advice if exposed.
  • Hypercorticism and Adrenal Suppression: High doses or prolonged use of nasal steroids can lead to systemic effects like adrenal suppression. If experiencing symptoms of excess steroid effects, gradually reduce the dose of Dymista under medical supervision.
  • Use of Cytochrome P450 3A4 Inhibitors: Medicines like ritonavir that affect liver enzymes can increase the levels of fluticasone in your body, potentially causing severe side effects. Avoid using Dymista with such drugs unless advised by your healthcare provider.
  • Effect on Growth: In children, corticosteroids can affect growth. Regularly monitor the growth of pediatric patients using Dymista.

Overdosage

If you use too much Dymista, it may cause side effects due to the azelastine hydrochloride or fluticasone propionate it contains.

For azelastine hydrochloride, which is in Dymista, overdosage is unlikely to cause serious problems, but it might increase drowsiness.

There is no specific antidote for Dymista, so general supportive care should be provided if overdosage occurs.

Keep Dymista away from children to prevent accidental ingestion, which can be harmful.

For fluticasone propionate, long-term overdosage may lead to symptoms of excessive steroid effects, like high cortisol levels. If you think you have used too much Dymista, contact your healthcare provider for advice.

Drug Interactions With Other Medications

No specific studies have been done to check how Dymista interacts with other drugs.

However, the interactions you might see with Dymista are likely to be similar to those of its ingredients.

This means the effects of Dymista when used with other medications may mirror those of azelastine hydrochloride and fluticasone propionate separately.

If you’re taking other medications or have any concerns about possible interactions, it’s important to talk to your healthcare provider for guidance.

Alternative Medications

Cost & Coupons

At Pharma Giant, we are dedicated to making healthcare affordable and accessible. One important medication that many rely on is Dymista, a nasal spray used to treat allergic rhinitis. It helps relieve symptoms such as sneezing, runny nose, and itchy eyes.

In the United States, the cost of Dymista can be as high as $250 for a single nasal spray, making it expensive for those who need it regularly. Our goal is to provide essential medications like Dymista at competitive prices, allowing you to prioritize your health without the worry of high costs.

Exclusive Discounted Prices for Dymista

We offer both the brand-name Dymista and its generic equivalent, Azelastine/Fluticasone, at reduced prices to help you manage your health more affordably.

Brand-Name Dymista Pricing

Strength Quantity Price (USD)
137mcg/50mcg 120 doses $144.95
240 doses $286.00
360 doses $423.00

Generic Equivalent (Azelastine/Fluticasone) Pricing

Strength Quantity Price (USD)
137mcg/50mcg 120 doses $134.95
240 doses $266.00
360 doses $393.00

By choosing Pharma Giant, you can access high-quality medications at prices that help you maintain your health without straining your budget.

Limited-Time Discount Offer

  • Promo Code: Use PGSAVE10 at checkout to receive a 10% discount on your Dymista order. This special offer is a great way to save on important medications while ensuring you receive high quality.
  • Offer Details: This discount is available for one-time use per customer, so take advantage while it lasts!

Ordering Process

  • Prescription Needed: A valid prescription is required to purchase Dymista or its generic equivalent. This ensures your safety and compliance with medical standards.
  • Bulk Ordering: You can order up to a 90-day supply to help manage your ongoing treatment needs and costs.

Quality Assurance & Fast Delivery

At Pharma Giant, we prioritize both the quality of our medications and the speed of our delivery service:

  • Fast Shipping: Your order is shipped from Canada to anywhere in the US within 3-5 business days, ensuring you receive your medications when you need them.
  • Secure Packaging: Every order is carefully packaged to protect the medication during shipping, maintaining its safety and integrity.

Choosing Pharma Giant means accessing affordable healthcare solutions without compromising on quality. We are committed to providing you with reliable medications, a straightforward ordering process, and fast, secure delivery to make your healthcare experience smooth and stress-free.

Frequently Asked Questions

Dymista is a nasal spray that combines two medications: azelastine, an antihistamine, and fluticasone, a corticosteroid. Azelastine helps reduce allergy symptoms by blocking histamine, while fluticasone reduces inflammation in the nasal passages. Together, they relieve symptoms like sneezing, runny nose, and nasal congestion.
Dymista can relieve symptoms of allergic rhinitis, including sneezing, runny nose, nasal congestion, and itchy or irritated nasal passages.
Dymista starts working within 5 minutes to effectively treat moderate to severe hay fever symptoms.
The recommended dosage of Dymista is 1 spray in each nostril twice daily.
If you miss a dose, use your regular dose the next day. Do not add an extra dose to make up for the missed one.
If your symptoms improve, it’s best to continue using Dymista as directed. Stopping treatment too early may cause your symptoms to return, especially if you are still exposed to allergens.
Store Dymista upright with the dust cap in place at room temperature between 68°F to 77°F (20°C to 25°C). Keep it away from light, and do not freeze or refrigerate the medication.
Yes, Dymista can be used all year round to relieve symptoms of hay fever and allergies. If you are 12 years of age or older and have been using Dymista consistently for 6 months, consult with your doctor or pharmacist before continuing its use.
Do not use Dymista if you are allergic to azelastine hydrochloride, fluticasone propionate, or any of the other ingredients listed in the leaflet.
Yes, Dymista can be used by children aged 12 years and older to treat allergic rhinitis and allergy-induced symptoms in the nose and eyes.
Dymista may cause side effects such as drowsiness, nasal dryness or irritation, mild nosebleeds, and changes in taste. If any of these side effects persist or worsen, contact your doctor.
If you experience serious side effects such as severe nosebleeds, pain in your nose, a whistling sound when you breathe, eye pain, or signs of infection (like a persistent sore throat, white patches in your nose or throat, fever, or chills), contact your doctor immediately.
Dymista may interact with certain drugs, such as ritonavir, ketoconazole, alcohol, or other central nervous system depressants.
You should use Dymista only for as long as your doctor recommends. It is suitable for long-term use as needed for your allergy symptoms.
If you accidentally use too much Dymista on one occasion, there’s generally no need to worry. However, if you use it excessively over a long period, it might cause unwanted side effects in your nose or body.
  • Shake the bottle: Gently shake the bottle before each use to mix the medication.
  • Prime the spray: If using the spray for the first time, or if it hasn’t been used for a while, pump the spray until a fine mist appears.
  • Position the nozzle: Insert the nozzle into one nostril while closing the other nostril with your finger.
  • Spray while inhaling: Breathe in gently through your nose and press down on the spray pump to release the medication.
  • Repeat for the other nostril: Use the same technique for the other nostril.
  • Clean the nozzle: Wipe the nozzle with a clean tissue and replace the cap after use.
  • Avoid blowing your nose: Try not to blow your nose for a few minutes after using the spray.
You should stop using Dymista if advised by your doctor, especially if you have been using it consistently for 6 months.
Dymista should be used during pregnancy only if the potential benefit to the mother outweighs the potential risk to the baby. There have been no specific studies on the effects of Dymista during pregnancy.
Common side effects of Dymista include drowsiness, nasal dryness or irritation, mild nosebleeds, and changes in taste. If these effects persist or worsen, contact your doctor or pharmacist.
Dymista can cause tiredness, especially in children and people who use it for a long time or in high doses.

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

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Price Match Guarantee

Price Match Guarantee

We are committed to providing fair, competitive pricing on all medications. If you find a lower price on the same product at another verified Canadian online pharmacy, we’ll match it.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online pharmacy with a verifiable address.
  • The competitor’s price must be current and active (not from a past or future promotion).
  • The product must be identical in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be submitted before placing an order — adjustments cannot be made after purchase.
  • Price matching does not apply to used or expired products.
  • Requests can be submitted via live chat or phone prior to completing your order.

Note: Price matching does not currently apply to Mounjaro® , Ozempic® or Saxenda®. However, this policy may be updated in the future.

Kenneth Fill, PharmD, MBA Fill

Kenneth Fill, PharmD, MBA, is a clinical pharmacist specialist and medical writer with a strong background in ambulatory care, pharmacogenomics, and medical content development. Based in the state of Michigan, he provides expert guidance on chronic disease state management. Kenneth completed his PharmD and MBA at the University of Toledo and pursued post-graduate residency training in ambulatory care and community-based pharmacy. His diverse background also includes academic detailing, clinical education, and interdisciplinary collaboration to enhance patient outcomes.