Buy Epiduo from Canada
from$129.95
$296
Adapalene / Benzoyl Peroxide (Generic) Adapalene, Benzoyl Peroxide
Select product strength & quantity:
Prescription Required
Ships within 4-10 Business Days
Express Ships from Canada
Product of Canada
from$149.95
$513
Epiduo Adapalene, Benzoyl Peroxide
Select product strength & quantity:
Prescription Required
Ships within 14-20 Business Days
Express Ships from UK
Product of UK

SAVE 10% on first order

with coupon code:

PGSAVE10

What is Epiduo?

Epiduo (adapelene and benzoyl peroxide) is a prescription medication that can also be applied topically. It is primarily given as an acne vulgaris treatment.

Acne vulgaris is a typical kind of skin disease, which primarily comprises blackheads, whiteheads, and pimples.

You are supposed to report to your doctor before you start using this Epiduo gel if you have an area of skin cut or sunburned, and such other medical conditions.

Therefore, a pregnant or impregnating woman must also consult her doctor because it is not known if Epiduo affects an unborn baby. A breastfeeding woman also has to inform her doctor because it is also unknown if it passes to the breast milk.

How Does Epiduo Work?

Epiduo gel contains two active ingredients-adapalene and benzoyl peroxide. Combining both ingredients assists with the effective treatment of acne.

It removes the occlusion and opens pores, thus reducing redness, swelling, and inflammation. It works by stimulating some receptors in the skin that induce the cells to proliferate appropriately.

On the other hand, benzoyl peroxide kills the bacteria causing acne and also stimulates the natural process of shedding dead skin cells by the skin.

All these components are going to reduce the manifestations of acne by attacking the different causes and, therefore, your skin will appear clearer and better.

Dosage Information and Usage

Dosage Form and Strengths of Epiduo

Epiduo gel is white to very pale yellow, an opaque gel. In each gram, Epiduo contains 1 mg (0.1%) of adapalene and 25 mg (2.5%) benzoyl peroxide.

When applied to the skin, the combination works quite well to fight pimples.

Usage

Epiduo gel is only taken through a topical route, that is, by application directly on the skin, while it is not taken orally, and neither applied in the eyes and vagina.

First of all, the facial or trunk area affected is cleansed with a non-comedogenic cleanser and blotted dry.

Then apply a thin layer of the gel every day, spreading it all over the face areas that get the application. Use about a pea-sized amount per area to be covered like the forehead, the chin, and the cheeks.

Avoid getting the gel on your eyes, lips, or broken skin to steer clear of irritation.

Take note that applying too much or applying too often maximizes the risk of skin irritation.

Always let the gel dry completely before dressing up again to prevent it from bleaching any clothing or hair.

Storage Information

Epiduo gel should be stored at room temperature, between 68°F and 77°F (20°C to 25°C). No issues will be involved with storage if stored in a cooler location up to 59°F (15°C) or warm as high as 86°F (30°C). Store the gel in a dry environment, out of direct sunlight and moisture, and store it as supplied at as wide a range of temperatures as possible to preserve its strength.

Side Effects of Epiduo

Common Side Effects

  • Redness of the skin
  • Dryness of the skin
  • Swelling in the treated area
  • Scaling or flaking
  • Stinging or burning sensations

Serious but Rare Side Effects

  • Severe skin reactions that last longer than 4 weeks
  • Increased irritation or discomfort in the treated area

Warnings and Precautions

  • Avoid exposure to sun and sun lamps: Exposure to sun and sun lamps has to be minimal during the period of taking the medication. This is because the gel increases skin sensitivity; therefore it may cause burns or irritation. If you have to spend time outdoors, apply sunscreen and protective garments including hats.
  • Local cutaneous reactions: You might have erythema, desquamation and dryness, or stinging and burning which are very marked in the first four weeks of the therapy. These are mild to moderate and diminish over time. If the effects are severe then you can use a moisturizer can reduce the application of the gel or cease it altogether.
  • Avoid irritating products: Avoid any other products that may irritate your skin which include harsh soaps, abrasive cleansers, or cosmetics containing a high percentage of alcohol. Such drugs may heighten risks of irritation when used with Epiduo gel and lower your effectiveness in treatment.
  • Skin areas to avoid: Epiduo should not be applied to cut, scraped, or sunburned skin. Irritation is likely to spread or even cause other forms of skin problems in such areas. In addition, users should not apply such hair removal techniques as waxing on treated skin as this will irritate the skin further.

Drug Interactions With Other Medications

Use Epiduo gel with caution during the combination treatment with topical acne therapies. Several topical products for acne especially those products that peel, exfoliate, and rub may irritate the skin more.

This has the effect that your skin may become sensitive or uncomfortable. Since there are no available reports about how Epiduo would react with any other kind of medication, it is advisable to ask your doctor or pharmacist before starting with other treatments besides Epiduno.

Alternative Medications

  • Differin (adapalene)
  • Azelex (azelaic acid)
  • Finacea (azelaic acid)
  • Onexton (benzoyl peroxide/clindamycin)
  • Aczone (dapsone)
  • Erygel (erythromycin topical)
  • Amzeeq (minocycline topical)
  • Accutane (isotretinoin)
  • Aldactone (spironolactone)

Cost & Coupons

At Pharma Giant, we at least know that your health matters most, and getting the medicine you need shouldn’t be an emptying of wallet.

We are always available to provide drugs like Epiduo at competitive prices.

Epiduo is a very widely used medication by people fighting acne. However, in the United States, for example, it can cost around $409.78 at most.

Our goal should be to make those critical treatments as affordable and accessible as possible.

Big Savings on Epiduo

It should not have to be expensive to take care of your health. Pharma Giant makes health care easy on your pocketbook.

Now, take a look at our prescriptions for Epiduo:

  • 0.1%/2.5% – 45 g – $149.95

Generic:

  • 0.1%/2.5% – 70 g – $140.22

We provide quality medicine at prices that won’t break the bank. With Pharma Giant, you can manage your healthcare costs without stress.

Special Discount Offer

  • Coupon Code: While checking out, use the code PGSAVE10 to receive an extra 10% discount on your Epiduo order. Save on your expenses with this amazing offer while getting proper treatment.
  • Offer Details: This is a one-time use discount per customer. Don’t miss this opportunity.

How to Order

  • Prescription Required: You will need a valid prescription to buy Epiduo.
  • Bulk Purchases: You can order a 90-day supply to save more time and money.

Choosing Pharma Giant means you get to focus on your health without worrying about high costs.

Frequently Asked Questions

Epiduo is applied to reduce acne breakouts, clean the pores, and reduce inflammation.
Avoid harsh soaps, abrasive cleansers, alcohol-containing products with astringents, spices, or limes that irritate the skin.
Yes, Epiduo will make your acne worse to start. But this is only only temporary. It should be getting better within 2-12 weeks.
Epiduo can start manifesting results of acne within two weeks, with full and ultimate effects typically realized within a period of up to 12 weeks.
Immediately discontinue the use of Epiduo and notify your healthcare professional if you have or develop irritation such as swelling of the face or tongue, throat tightness, hives, itching, or difficulty breathing.
Yes, when you stop using Epiduo too soon, acne is likely to recur. Avoid this by continuing the medication as your prescriber instructs you to do so.
Epiduo is recommended for mild to severe kind of acne conditions, includes pimples, blackheads, and whiteheads. In a few cases, they prescribe the same when OTC does not work.
Apply Epiduo on clean, dry, skin with a pea-sized amount once daily. It should be spread lightly over the affected areas but over eyes, lips, and broken skin.
Other acne products should not be used with Epiduo, especially those that have benzoyl peroxide or retinoids. Avoid also waxing the areas that have Epiduo applied on the skin.
It should be applied following the use of Epiduo with moisturizer as it will prevent the possible intractable dryness, peeling, and irritation with Epiduo.
Apply Epiduo once a day on clear and dry skin. All over the face, it should be applied over the affected area, avoiding the eyes and the lips, and wash the hands afterward.
Epiduo causes skin irritation from some ingredients, such as propylene glycol. Other recommendations avoid products containing irritants and reduce exposure to sunlight.
It is safe for use for long-term use since it does not contain antibiotics; it can hence be used on top of oral antibiotics in more aggressive acne according to guidelines of treatment.

Applications of Epiduo can be found on the face, chest, and back.
No, the brand Epiduo is available only by prescription. It also is used to cure mild to acute breakouts of acne but by topical application.
No, use Epiduo during pregnancy. The adapalene ingredient in this drug has been classified as harmful to an unborn baby. You should talk to your doctor regarding the risks and benefits if you get pregnant while using it. Therefore, it has not been established that Epiduo passes to the breast milk through skin application, so talk to your doctor while breastfeeding.
Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Continue your dosing schedule as usual. Do not apply additional gel to make up for a missed dose.
Store Epiduo gel between 68°F to 77°F (20°C to 25°C). It is acceptable if short exposure has temperatures as low as 59°F (15°C) or as high as 86°F (30°C). Store in a cool, dry place away from direct sunlight and moisture.
If you have sensitive skin, then first see a doctor before using Epiduo or Epiduo Forte as it can seriously irritate the skin. Your doctor will instead prescribe to you a form of medication for acne that is safe for your skin type.
Yes, Epiduo may cause peeling or dryness. Irritation is to be expected with this topical medication; its severity is, in general, mild to moderate, but can include redness, dryness, scaling, stinging, or burning. Side effects generally peak within the first few weeks of treatment and otherwise may spontaneously improve.

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

Have a prescription?

Order Epiduo online today and enjoy a host of benefits, including:

Customer Reviews
  • Cost Savings: Buy Epiduo at LOWER PRICES compared to the US
  • Bulk Order Discounts: Enjoy additional savings with bulk orders of Epiduo (up to 90-day supply)
  • Reliable Express Shipping: Fast and discreet delivery shipped directly to your doorstep
  • Exceptional Customer Service: Have a question? We’re delighted to help via live chat, email, or phone
  • Easy & Secure Ordering: Seamless online or phone ordering at 1-888-513-2294
  • SAVE 10% on first order with coupon code: PGSAVE10

Price Match Guarantee

Price Match Guarantee

We are committed to providing fair, competitive pricing on all medications. If you find a lower price on the same product at another verified Canadian online pharmacy, we’ll match it.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online pharmacy with a verifiable address.
  • The competitor’s price must be current and active (not from a past or future promotion).
  • The product must be identical in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be submitted before placing an order — adjustments cannot be made after purchase.
  • Price matching does not apply to used or expired products.
  • Requests can be submitted via live chat or phone prior to completing your order.

Note: Price matching does not currently apply to Mounjaro® , Ozempic® or Saxenda®. However, this policy may be updated in the future.