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What is Glumetza?

Glumetza is an extended-release once-a-day medication prescribed for adults with type 2 diabetes to help control blood sugar levels, along with a healthy diet and exercise. It is sometimes used in combination with other antidiabetic medications.

Glumetza belongs to the drug class biguanides. These medications work by restoring the body’s response to insulin and decreasing the amount of sugar produced by the liver and absorbed by the body. It also delays the onset of diabetes-related problems.

Glumetza is not recommended:

  • If you are allergic or have had an allergic reaction to Glumetza or ingredients in Glumetza.
  • If you have type 1 diabetes.
  • For patients younger than 18 years of age.
  • If you have severe kidney problems
  • If you have diabetic ketoacidosis.
  • If you have metabolic acidosis.

What are the Indications for Glumetza?

Glumetza is a slow-release medication approved to treat high blood sugar in people with type 2 diabetes.

How is Glumetza used?

Storage

Glumetza should be stored in its original packaging at room temperature between 68°F and 77°F (20°C and 25°C) with excursions permitted between 59°F and 86°F (15°C and 30°C).

Keep it out of reach of children and away from moisture, heat, and light.

Instruction

Glumetza should be part of a complete treatment program that may include diet, exercise, weight management, and blood sugar testing. Make sure that you follow your doctor’s instructions.

Take Glumetza orally once a day in the evening with a meal. If you miss a dose, skip the dose, and take the next dose at the regular time. Do not catch up by taking two doses at once.

Do not change your dosage, take more than what is prescribed, or stop using Glumetza without consulting with your doctor. If you took more than prescribed, contact your doctor immediately or seek emergency medical care.

Dosage

Glumetza is available as a white, oval-shaped extended-release tablet in these strengths: 500 mg and 1 000 mg.

Your doctor will determine your dosage depending on your individual health. The usual starting dose is 500 mg once a day in the evening with food. The maximum recommended dosage is 2 000 mg.

Side Effects

It’s important to understand that although Glumetza is FDA-approved, it comes with side effects that may or may not affect you.

Before starting, you should discuss possible side effects with your doctor or pharmacist.

Because of its extended-release formulation, it releases the medication slowly over time and can reduce the side effects.

Common Side Effects

Not all side effects require medical attention. As your body adjusts to Glumetza, side effects may go away. Tell your doctor if you experience the following symptoms, and they become severe or do not go away on their own.

  • Diarrhea
  • Nausea
  • Metallic taste in mouth
  • Weakness
  • Upset stomach

An empty tablet shell may appear in your stool but is harmless because the medication has already been absorbed by your body.

Serious Side Effects

Severe adverse reactions while taking Glumetza may occur. Seek emergency medical care or call 911 if you experience any of the following symptoms:

  • Severe allergic reaction: a rash over your whole body, sweating, extreme drowsiness, swelling of your face, tongue, or throat, difficulty breathing or swallowing, feeling faint, dizziness, rapid heartbeat, shortness of breath, or becoming confused.
  • Lactic acidosis: fast and shallow breathing, muscle pain/cramping, slow/irregular heartbeat, unusual sleepiness/tiredness/weakness, feeling cold, vomiting, or unusual stomach ache.
  • Hypoglycemia: headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heartbeat, sweating, shaking, feeling jittery.
  • Vitamin B deficiency: may cause decreased vitamin B12 levels, and your doctor will do regular blood tests while you are taking this medication.

The information above does not list all possible side effects. Contact your doctor or pharmacist if you experience any side effects not listed. You or your doctor may report side effects to the FDA by calling 1-800-FDA-1088.

Warnings & Precautions

Before using Glumetza, tell your doctor or pharmacist:

  • If you are allergic to Glumetza or any of the ingredients in Glumetza.
  • If you are pregnant or plan to become pregnant.
  • If you are breastfeeding or plan to breastfeed.

Lactic acidosis

Glumetza can cause lactic acidosis, a build-up of acid in the blood which can cause death. Let your doctor know if you have fast and shallow breathing, muscle pain/cramping, slow/irregular heartbeat, unusual sleepiness/tiredness/weakness, feeling cold, vomiting, or unusual stomach ache.

Low blood sugar

Glumetza may cause low blood sugar, especially if you consume large amounts of alcohol, do unusually heavy exercise, or don’t consume enough calories. Make sure you eat regular meals and do not skip any meals.

X-ray/scanning procedures

Let your doctor or dentist know that you take Glumetza before going for surgery or any X-ray/scanning procedure that uses iodinated contrast (a dye injected into your veins). You may need to stop this medication for a short time before the surgery/procedure.

Pregnant or Planning to Become Pregnant

It is not known if Glumetza will harm an unborn baby. Tell your doctor if you are pregnant or planning to become pregnant and about the best way to control your blood sugar levels while you are pregnant.

Breastfeeding or Planning to Breastfeed

Glumetza may pass into breast milk and could harm your baby. Speak to your doctor if you are breastfeeding or planning to start breastfeeding.

Interactions & Contraindications

Before using Glumetza, tell your doctor or pharmacist if you take any medications, herbal supplements, and vitamins.

Do not use Glumetza if you suffer from acute or chronic metabolic acidosis, including ketoacidosis, with or without coma, or if you are hypersensitive to Glumetza or any of its ingredients.

Diabetic ketoacidosis should be treated with insulin.

Beta-blocker medications

Beta-blockers may prevent a fast/pounding heartbeat, a symptom of hypoglycemia, and should be used with caution.

Frequently Asked Questions

Glumetza contains the active ingredient metformin hydrochloride.

Inactive ingredients:

  • 500 mg tablet: coloring, hypromellose, magnesium stearate, microcrystalline cellulose, and polyethylene oxide.
  • 1 000 mg tablet: colloidal silicon dioxide, polyvinyl alcohol, crospovidone, glyceryl behenate, polyacrylate dispersion, hypromellose, talc, polyethylene glycol, titanium dioxide, simethicone emulsion, polysorbate, and coloring.

Glumetza is a slow-release medication that is used to treat high blood sugar in people with type 2 diabetes.

Glumetza is available as a white, oval-shaped extended-release tablet in these strengths: 500 mg and 1 000 mg.

Glumetza is approved for use in adults over the age of 18 years with type 2 diabetes.

Glumetza should not be used if you are allergic to Glumetza or any ingredients in Glumetza, are younger than 18 years, or suffer from severe kidney problems or diabetic ketoacidosis.

Serious allergic reactions include severe rash or itching, swelling in the face, lips, tongue, or throat, severe dizziness, and trouble breathing.

Avoid drinking alcohol, doing unusually strenuous exercise, or skipping meals, as it can lower blood sugar levels.

Take orally once daily in the evening with a meal. Make sure that you stick to a healthy diet and exercise while taking Glumetza.

If you miss a dose, skip the dose, and take the next dose at the regular time. Do not catch up by taking two doses at once.

Yes, with a prescription, you can purchase Glumetza online. Buying medications online is convenient and often less expensive than purchasing them at your local pharmacy.