What are the Indications for Glumetza?
Glumetza is a slow-release medication approved to treat high blood sugar in people with type 2 diabetes.
How is Glumetza used?
Glumetza should be stored in its original packaging at room temperature between 68°F and 77°F (20°C and 25°C) with excursions permitted between 59°F and 86°F (15°C and 30°C).
Keep it out of reach of children and away from moisture, heat, and light.
Glumetza should be part of a complete treatment program that may include diet, exercise, weight management, and blood sugar testing. Make sure that you follow your doctor’s instructions.
Take Glumetza orally once a day in the evening with a meal. If you miss a dose, skip the dose, and take the next dose at the regular time. Do not catch up by taking two doses at once.
Do not change your dosage, take more than what is prescribed, or stop using Glumetza without consulting with your doctor. If you took more than prescribed, contact your doctor immediately or seek emergency medical care.
Glumetza is available as a white, oval-shaped extended-release tablet in these strengths: 500 mg and 1 000 mg.
Your doctor will determine your dosage depending on your individual health. The usual starting dose is 500 mg once a day in the evening with food. The maximum recommended dosage is 2 000 mg.
It’s important to understand that although Glumetza is FDA-approved, it comes with side effects that may or may not affect you.
Before starting, you should discuss possible side effects with your doctor or pharmacist.
Because of its extended-release formulation, it releases the medication slowly over time and can reduce the side effects.
Common Side Effects
Not all side effects require medical attention. As your body adjusts to Glumetza, side effects may go away. Tell your doctor if you experience the following symptoms, and they become severe or do not go away on their own.
- Metallic taste in mouth
- Upset stomach
An empty tablet shell may appear in your stool but is harmless because the medication has already been absorbed by your body.
Serious Side Effects
Severe adverse reactions while taking Glumetza may occur. Seek emergency medical care or call 911 if you experience any of the following symptoms:
- Severe allergic reaction: a rash over your whole body, sweating, extreme drowsiness, swelling of your face, tongue, or throat, difficulty breathing or swallowing, feeling faint, dizziness, rapid heartbeat, shortness of breath, or becoming confused.
- Lactic acidosis: fast and shallow breathing, muscle pain/cramping, slow/irregular heartbeat, unusual sleepiness/tiredness/weakness, feeling cold, vomiting, or unusual stomach ache.
- Hypoglycemia: headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heartbeat, sweating, shaking, feeling jittery.
- Vitamin B deficiency: may cause decreased vitamin B12 levels, and your doctor will do regular blood tests while you are taking this medication.
The information above does not list all possible side effects. Contact your doctor or pharmacist if you experience any side effects not listed. You or your doctor may report side effects to the FDA by calling 1-800-FDA-1088.
Warnings & Precautions
Before using Glumetza, tell your doctor or pharmacist:
- If you are allergic to Glumetza or any of the ingredients in Glumetza.
- If you are pregnant or plan to become pregnant.
- If you are breastfeeding or plan to breastfeed.
Glumetza can cause lactic acidosis, a build-up of acid in the blood which can cause death. Let your doctor know if you have fast and shallow breathing, muscle pain/cramping, slow/irregular heartbeat, unusual sleepiness/tiredness/weakness, feeling cold, vomiting, or unusual stomach ache.
Low blood sugar
Glumetza may cause low blood sugar, especially if you consume large amounts of alcohol, do unusually heavy exercise, or don’t consume enough calories. Make sure you eat regular meals and do not skip any meals.
Let your doctor or dentist know that you take Glumetza before going for surgery or any X-ray/scanning procedure that uses iodinated contrast (a dye injected into your veins). You may need to stop this medication for a short time before the surgery/procedure.
Pregnant or Planning to Become Pregnant
It is not known if Glumetza will harm an unborn baby. Tell your doctor if you are pregnant or planning to become pregnant and about the best way to control your blood sugar levels while you are pregnant.
Breastfeeding or Planning to Breastfeed
Glumetza may pass into breast milk and could harm your baby. Speak to your doctor if you are breastfeeding or planning to start breastfeeding.
Interactions & Contraindications
Before using Glumetza, tell your doctor or pharmacist if you take any medications, herbal supplements, and vitamins.
Do not use Glumetza if you suffer from acute or chronic metabolic acidosis, including ketoacidosis, with or without coma, or if you are hypersensitive to Glumetza or any of its ingredients.
Diabetic ketoacidosis should be treated with insulin.
Beta-blockers may prevent a fast/pounding heartbeat, a symptom of hypoglycemia, and should be used with caution.