Ibrance (Palbociclib)
Ibrance
From$7395
$13500
Ibrance Palbociclib
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Select product strength & quantity:
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What is Ibrance (palbociclib)?

Ibrance is a prescription oral medication developed by Pfizer used to treat metastatic breast cancer primarily in adult patients.

Ibrance belongs to the drug class, CDK 4/6 inhibitors. These medications work by slowing the growth of cancer cells, including healthy cells.

Ibrance is not recommended:

  • If you are allergic or have had an allergic reaction to Ibrance or ingredients in Ibrance
  • If you are pregnant or breastfeeding
  • For patients under 18 years of age

What are the Indications for Ibrance?

Ibrance is approved for the treatment of hormone receptor (HR) +, human epidermal growth factor receptor 2 (HER2), or metastatic breast cancer in male and female adult patients.

Ibrance is used in combination with other therapies, such as an aromatase inhibitor as initial endocrine-based therapy, or with fulvestrant in those whose disease has progressed after endocrine therapy.

How is Ibrance used?

Storage

Ibrance should be stored in the original package between 68°F and 77°F (20°C and 25°C) away from heat and moisture.

Keep out of reach of children.

Instruction

Take Ibrance by mouth, as directed by your doctor, with food at the same time every day. Swallow the capsule or tablet whole. Do not chew, split, or crush the capsule or tablet. Do not take any broken Ibrance capsule or tablet.

If you miss a dose, skip the missed dose and take your next dose as scheduled. If you threw up your dose, do not take another dose. Continue to take your next dose as scheduled.

Do not change your dosage and take more than what is prescribed, or stop using Ibrance without consulting your doctor. If you took more than prescribed, contact your doctor immediately or seek emergency medical care.

Dosage

Ibrance is available in both capsule and tablet formulations at 75 mg, 100 mg, and 125 mg strengths. Capsules and tablets are not interchangeable on a mg-to-mg basis due to differences in formulation. Ibrance treatment is taken in a 28-day cycle. The recommended starting dose is 125 mg once daily for 21 days with 7 days off for a total of 28 days.

Side Effects

It’s important to understand that although Ibrance is FDA approved, it comes with side effects that may or may not affect you.

Before starting Ibrance, you should discuss possible side effects with your doctor or pharmacist.

Common Side Effects

Not all side effects require medical attention. As your body adjusts to Ibrance, side effects may go away. Tell your doctor if you experience the following symptoms, and they become severe or do not go away on their own.

  • Nausea
  • Dizziness
  • Vomiting
  • Anxiety
  • Constipation
  • Rash
  • Loss of appetite
  • Hair thinning or loss
  • Sore mouth
  • Tiredness

Serious Side Effects

Severe adverse reactions while taking Ibrance may occur. Seek emergency medical care or call 911 if you experience any of the following symptoms:

  • Severe allergic reaction: severe rash or itching, swelling in the face, lips, tongue, or throat, rapid heartbeat, fainting or dizziness, or problems breathing or swallowing.
  • Low white blood cell counts (neutropenia): weakness, dizziness, shortness of breath, bleeding easily, bruising easily, or nosebleeds.
  • Infections
  • Lung problems: chest pain, cough, shortness of breath, or trouble breathing.

The information above does not list all possible side effects. Contact your doctor or pharmacist if you experience any side effects not listed. You or your doctor may report side effects to the FDA by calling 1-800-FDA-1088.

Warnings & Precautions

Before using Ibrance, tell your doctor or pharmacist:

  • If you are allergic to Ibrance or any ingredients in Ibrance
  • If you have any signs of infection, including fever and chills
  • If you have or have had liver or kidney problems
  • If you are pregnant or plan to become pregnant
  • If you are breastfeeding or plan to breastfeed

Low white blood cell counts (neutropenia)

Taking Ibrance may result in low white blood cell counts. This may lead to serious infections and death. Your doctor will check your white blood cell count before treatment with Ibrance and while you are taking Ibrance. Depending on your white blood cell count, your doctor may lower your dose or discontinue treatment of Ibrance.

Lung problems (pneumonitis)

Taking Ibrance may result in the inflammation of your lungs, which may become severe and lead to death.

Signs and symptoms include shortness of breath, trouble breathing, chest pain, and cough. Contact your doctor immediately if you exhibit any of these symptoms.

Infections

Taking Ibrance can increase your risk of infections, which can become serious and lead to death.

Signs and symptoms include chills, fever, confusion, or weakness. Contact your doctor immediately if you exhibit any of these symptoms.

Male Fertility

Taking Ibrance may cause infertility problems in male patients, resulting in the inability to conceive children. Contact your doctor if you have any questions or concerns regarding fertility.

Pregnant or Planning to Become Pregnant

Taking Ibrance while pregnant can impact the unborn baby and cause harm. If you are a female patient, your doctor will conduct a pregnancy test before starting treatment with Ibrance. If you are not pregnant but could become pregnant, you should use effective contraceptives during treatment with Ibrance and continue to use effective contraceptives for at least 3 weeks after discontinuing Ibrance. If you become pregnant while on Ibrance, tell your doctor immediately.

If you are a male patient with female partners, you should use an effective contraceptive during treatment of Ibrance and continue to use effective contraceptives up to 3 months after discontinuing Ibrance. If your partner becomes pregnant while you are using Ibrance, tell your doctor right away.

Breastfeeding or Planning to Breastfeed

Studies have not been conducted to determine if Ibrance will pass through to human milk. However, due to severe possible side effects, breastfeeding should be discontinued while on treatment with Ibrance, including up to 3 weeks after discontinuing Ibrance.

Drug Interactions & Contraindications

Before using Ibrance, tell your doctor or pharmacist if you take any medications, herbal supplements, or vitamins.

CYP3A inhibitors

Taking a CYP3A inhibitor with Ibrance increases the potency of Ibrance which can lead to an increased risk in side effects. CYP3A inhibitors should be avoided while taking Ibrance unless otherwise directed.

CYP3A inhibitors include itraconazole, ketoconazole, clarithromycin, voriconazole, telaprevir, nelfinavir, and ritonavir.

Grapefruit

Consuming grapefruit while on treatment with Ibrance may increase the potency of Ibrance. This can lead to an increased risk of severe side effects, including bleeding, nausea, vomiting, and low blood cells. Grapefruit should be avoided while on treatment with Ibrance unless otherwise directed.

CYP3A inducers

Taking a CYP3A inducer with Ibrance may significantly reduce the potency of Ibrance. CYP3A inducers should be avoided while taking Ibrance unless otherwise directed.

CYP3A inducers include phenytoin, rifampin, carbamazepine, enzalutamide, and St John’s Wort.

Buy Ibrance: Medication Cost & Coupons

For those looking to buy Ibrance, significant cost savings can be realized. The cost of prescription medications can be a significant burden, especially in the United States where prices are often high. A prime example of this is the drug Ibrance. In the U.S., the cost for Ibrance, particularly the 75mg dosage with 21 tablets, can exceed $7,395 for individuals without insurance coverage. This high price point can make it challenging for many patients to access the medication they need.

However, there is a cost-effective solution available through Pharma Giant (PG). By obtaining a prescription from a doctor, Americans can order Ibrance online securely and conveniently from a licensed & trusted Canadian pharmacy through PG. At Pharma Giant, the price for Ibrance is significantly lower, available starting at $7,395.00 per 21 tablets. This presents a substantial saving opportunity for those requiring this medication.

Pharma Giant operates as a reliable and efficient service. It serves as a bridge connecting U.S. patients with licensed pharmacies. The fulfillment process is streamlined for efficiency and reliability, ensuring that once an order is placed, a licensed pharmacy will promptly fulfill the prescription, maintaining the highest standards of quality and safety.

One of the key aspects of this service is the expedited shipping process. Once an order is placed, the drugs are express shipped to the United States, typically arriving within 3-5 business days. This quick turnaround time ensures that patients receive their order promptly, minimizing any potential disruption to their treatment plans.

Ibrance Coupon Offer

To make this deal even more attractive, PG offers a special discount for first-time customers. By using the coupon code PGSAVE10, new customers can save 10% on their first order. This additional discount further lowers the financial barrier, making essential medications like Ibrance more accessible to those in need.

By choosing to order through Pharma Giant, patients in the U.S. can manage their health effectively while also making significant savings on their medication costs.

Strength Quantity Total Price Price per Tablet
75mg 21 tabs $7,395.00 $352.14
42 tabs $14,770.00 $351.67
63 tabs $22,125.00 $351.19
100mg 21 tabs $7,395.00 $352.14
42 tabs $14,770.00 $351.67
63 tabs $22,125.00 $351.19
125mg 21 tabs $7,395.00 $352.14
42 tabs $14,770.00 $351.67
63 tabs $22,125.00 $351.19

Use the coupon code PGSAVE10 to save 10% on your first order!

Frequently Asked Questions

Ibrance contains the active ingredient palbociclib. In capsule form, Ibrance contains the inactive ingredients: microcrystalline cellulose, lactose monohydrate, sodium starch glycolate, colloidal silicon dioxide, magnesium stearate, and hard gelatin capsule shells. The light orange, light orange/caramel, and caramel opaque capsule shells contain gelatin, red iron oxide, yellow iron oxide, and titanium dioxide. The printing ink contains shellac, titanium dioxide, ammonium hydroxide, propylene glycol, and simethicone. In tablet form, Ibrance contains the inactive ingredients: microcrystalline cellulose, colloidal silicon dioxide, crospovidone, magnesium stearate, succinic acid, HPMC 2910/hypromellose, titanium dioxide, triacetin, and FD&C Blue #2/Indigo Carmine Aluminum Lake. In addition, the 75 mg and 125 mg tablets contain red iron oxide and the 100 mg tablets contain yellow iron oxide.
Ibrance is approved for the treatment of hormone receptor (HR)+, human epidermal growth factor receptor 2 (HER2), and metastatic breast cancer. Ibrance may be used alone or in combination with other therapies.
Ibrance is available in capsule or tablet forms.
Ibrance is approved for adult patients. Ibrance has not been determined to be safe and effective in pediatric patients.
Ibrance should not be used if you are allergic to Ibrance or any ingredients in Ibrance, in pediatric patients, or if you are pregnant or breastfeeding. Serious allergic reactions include severe rash or itching, swelling in the face, lips, tongue, or throat, rapid heartbeat, fainting or dizziness, or problems breathing or swallowing.
You should avoid being near people who may have an infection or maybe sick. Contact your doctor right away if you appear to have an infection or be sick.
Take Ibrance by mouth, as directed by your doctor, with food at the same time every day. Swallow the capsule or tablet whole. Do not crush, chew, or split the capsule or tablet.
If you miss a dose or threw up your dose, skip the dose. Take the next dose as scheduled.
Yes, with a prescription, you can purchase Ibrance online. Buying medications online is convenient and often less expensive than purchasing at your local pharmacy.

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

Have a prescription?

Order Ibrance online today and enjoy a host of benefits, including:

Customer Reviews
  • Cost Savings: Buy Ibrance at LOWER PRICES compared to the US
  • Bulk Order Discounts: Enjoy additional savings with bulk orders of Ibrance (up to 90-day supply)
  • Reliable Express Shipping: Fast and discreet delivery shipped directly to your doorstep
  • Exceptional Customer Service: Have a question? We’re delighted to help via live chat, email, or phone
  • Easy & Secure Ordering: Seamless online or phone ordering at 1-888-513-2294
  • SAVE 10% on first order with coupon code: PGSAVE10

Price Match Guarantee

Price Match Guarantee

We are committed to providing fair, competitive pricing on all medications. If you find a lower price on the same product at another verified Canadian online pharmacy, we’ll match it.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online pharmacy with a verifiable address.
  • The competitor’s price must be current and active (not from a past or future promotion).
  • The product must be identical in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be submitted before placing an order — adjustments cannot be made after purchase.
  • Price matching does not apply to used or expired products.
  • Requests can be submitted via live chat or phone prior to completing your order.

Note: Price matching does not currently apply to Mounjaro® , Ozempic® or Saxenda®. However, this policy may be updated in the future.

Kenneth Fill, PharmD, MBA Fill

Kenneth Fill, PharmD, MBA, is a clinical pharmacist specialist and medical writer with a strong background in ambulatory care, pharmacogenomics, and medical content development. Based in the state of Michigan, he provides expert guidance on chronic disease state management. Kenneth completed his PharmD and MBA at the University of Toledo and pursued post-graduate residency training in ambulatory care and community-based pharmacy. His diverse background also includes academic detailing, clinical education, and interdisciplinary collaboration to enhance patient outcomes.