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From$729
$6801
Prescription Required
Ships within 4-10 Business Days
Express Ships from Canada
Cold Shipment

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What is Idacio?

Idacio is a therapeutic biologic medication, specifically classified as a tumor necrosis factor (TNF) blocker. It is designed to block the immune-modulating effects of the naturally occurring TNF proteins in the body. By doing so, Idacio effectively reduces the inflammatory response that is often overactive in various autoimmune diseases.

Active Ingredient and Drug Class (TNF Blocker)

The active ingredient in Idacio is adalimumab-aacf, a monoclonal antibody that binds to and inhibits tumor necrosis factor-alpha (TNF-a). TNF-a is a cytokine, a type of protein involved in systemic inflammation, playing a key role in autoimmune and inflammatory processes.

FDA Approval and Biosimilarity to Humira

Idacio received FDA approval as a biosimilar to Humira, meaning it is highly similar to Humira in terms of safety, purity, and potency. Biosimilars undergo rigorous testing to ensure they match the reference product’s effectiveness and safety profile, offering a more cost-effective alternative without compromising therapeutic efficacy.

Medical Uses

Detailed Explanation of Conditions Treated by Idacio:

Rheumatoid Arthritis (RA)

Idacio is used to reduce symptoms and prevent the progression of moderate to severe RA, a chronic inflammatory disorder affecting the joints.

Juvenile Idiopathic Arthritis (JIA)

It is effective in treating moderate to severe JIA in children aged 2 years and older, helping to reduce pain and swelling in joints.

Psoriatic Arthritis (PsA)

Idacio is used for managing PsA, a form of arthritis associated with the skin condition psoriasis, characterized by joint pain and skin lesions.

Ankylosing Spondylitis (AS)

This medication helps in reducing symptoms in adults with active AS, a type of arthritis affecting the spine.

Crohn’s Disease

Idacio is indicated for inducing and maintaining remission in moderate to severe Crohn’s disease in adults and in pediatric patients ?6 years old who have had an inadequate response to conventional therapy.

Ulcerative Colitis (UC)

It is used for treating moderate to severe UC, another type of inflammatory bowel disease, in adults.

Plaque Psoriasis

Idacio is prescribed for adults with moderate to severe chronic plaque psoriasis, a skin condition characterized by red, scaly patches.

Other Potential Off-Label Uses

While not officially approved for other conditions, Idacio may be used off-label for various other autoimmune or inflammatory diseases, as determined appropriate by healthcare providers.

How Idacio Works

Mechanism of Action in the Body

Idacio, containing adalimumab-aacf, is a TNF (tumor necrosis factor) blocker. It works by targeting and neutralizing TNF-alpha, a specific protein in the body’s immune system that plays a key role in causing inflammation and immune system disorders. By inhibiting TNF-alpha, Idacio reduces inflammatory responses, which is crucial in treating autoimmune conditions where the body’s immune system mistakenly attacks its own tissues.

Impact on Immune System and Inflammation

The suppression of TNF-alpha by Idacio leads to a decrease in the inflammatory process that contributes to the symptoms and progression of various autoimmune diseases. This action helps in reducing symptoms like pain, swelling, and damage to affected body parts. It also slows down disease progression, improving the quality of life for patients with conditions like rheumatoid arthritis, psoriatic arthritis, and Crohn’s disease.

Dosage and Administration

Recommended Dosages for Various Conditions

  • Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis: Adults typically receive 40 mg every other week.
  • Crohn’s Disease, Ulcerative Colitis: The initial dose for adults is 160 mg, followed by 80 mg two weeks later, then 40 mg every other week starting on Day 29.
  • Plaque Psoriasis: Adults receive an initial dose of 80 mg, followed by 40 mg every other week starting one week after the initial dose.
  • Dosages for children vary based on weight and the condition being treated.

Administration Method (Subcutaneous Injection)

Idacio is administered through subcutaneous injection, usually in the front of the thigh or abdomen. Patients or caregivers can inject Idacio after proper training in subcutaneous injection techniques. The injection site should be rotated each time to reduce injury under the skin.

Dosage Forms Available (Prefilled Syringe or Pen)

Idacio is available in single-dose prefilled pens and prefilled glass syringes, each containing a 40 mg/0.8 mL dose. These forms are designed for ease of use and to facilitate self-administration.

Side Effects and Risks

Common Side Effects

Common side effects of Idacio include infections (e.g., upper respiratory, sinusitis), injection site reactions, headache, and rash. These are generally manageable but should be monitored closely.

Serious Risks and Rare Side Effects

Serious risks include increased susceptibility to infections like tuberculosis and fungal infections, allergic reactions, and potential reactivation of hepatitis B in carriers. Rare side effects can include neurological reactions, hematological reactions, and worsening or new onset of congestive heart failure.

Boxed Warnings

Serious Infections: Patients are at an increased risk for developing serious infections that may lead to hospitalization or death. It’s crucial to monitor for signs of infection and discontinue Idacio if a serious infection develops.

Malignancy: There is an increased risk of lymphoma and other malignancies in children and adolescent patients treated with TNF blockers like Idacio. The risk of hepatosplenic T-cell lymphoma, although rare, is also noted.

Precautions and Contraindications

When Idacio Should Not Be Used

  • Idacio should not be used in patients with active, severe infections, including tuberculosis, sepsis, and opportunistic infections.
  • It is contraindicated in individuals with known hypersensitivity to adalimumab or any of its components.
  • Patients with moderate-to-severe heart failure should avoid using Idacio.

Necessary Precautions During Treatment

  • Before starting Idacio, patients should be tested for latent tuberculosis. If positive, treatment for TB should be initiated before administering Idacio.
  • Patients should be monitored for signs of infection during and after treatment, including the development of tuberculosis.
  • Caution is advised in patients with a history of demyelinating disease or those exhibiting symptoms suggestive of a nervous system disorder.

Potential Interactions with Other Medications

  • Idacio can interact with other immunosuppressants, increasing the risk of serious infections. This includes drugs like methotrexate, corticosteroids, and other biologics.
  • The combination of Idacio with live vaccines is not recommended.
  • Patients should inform their healthcare provider of all medications they are taking, including over-the-counter drugs and supplements.

Special Considerations

Use in Specific Populations (Children, Elderly)

  • The safety and efficacy of Idacio in children under 2 years of age have not been established.
  • In elderly patients, there may be an increased risk of infections and malignancies. Close monitoring and caution are advised.

Impact on Pregnancy and Breastfeeding

  • Idacio should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
  • It is not known whether adalimumab passes into breast milk. Nursing mothers should be cautious and discuss the risks and benefits with their healthcare provider.

Storage and Handling of the Medication

  • Idacio should be stored in the refrigerator and protected from light. It should not be frozen.
  • The medication can be allowed to reach room temperature for 15 to 30 minutes before injection, but should not be heated or re-refrigerated.

Patient Management and Monitoring

Monitoring Requirements During Treatment

  • Regular monitoring for signs of infection, liver function tests, and complete blood counts is recommended.
  • Patients should be monitored for new or worsening symptoms of heart failure, neurological disorders, or hematological reactions.

Managing Side Effects

  • Patients should be educated on recognizing the signs of serious side effects, including infections, allergic reactions, and neurological symptoms.
  • Immediate medical attention should be sought for symptoms like difficulty breathing, severe rash, or changes in vision.

Lifestyle and Dietary Considerations

  • Patients should be advised to avoid exposure to contagious diseases and practice good hygiene to reduce the risk of infections.
  • There are no specific dietary restrictions while on Idacio, but maintaining a balanced diet can support overall health.

Idacio Cost & Coupon

Your health is a priority, and purchasing essential medication shouldn’t be prohibitively expensive. At Pharma Giant, we offer affordable and accessible healthcare solutions.

In the United States, the cost of Idacio can reach as high as $6,801 for 2 pens (40mg/0.8ml). However, through Pharma Giant, you can access more affordable options:

Strength Form Quantity Pharma Giant Cost
40mg/0.8ml Pens 2 pens $1,399.00
40mg/0.8ml Pens 4 pens $2,760.00
40mg/0.8ml Pens 6 pens $4,110.00

Discount Code and Offer

Take control of your healthcare costs with Pharma Giant’s exclusive discount. Apply the code PGSAVE10 at checkout to receive a 10% discount on your Idacio purchase. This special offer is designed to help you save on essential medications without compromising on quality or affordability.

Assurance of Quality and Timely Delivery

At Pharma Giant, we are committed to providing top-tier medication and reliable delivery services right to your doorstep. Through our express shipping, you can anticipate receiving your order within just 3-5 business days across the US. Each order is meticulously packaged to ensure that your medication is protected during transit.

Please note: A prescription is required to order Idacio. Patients can save significantly on medication when they order online through Pharma Giant (pharmagiant.com).

Frequently Asked Questions

Idacio is a biosimilar to Humira (adalimumab), classified as a TNF (tumor necrosis factor) blocker. It’s used to treat various autoimmune conditions by reducing inflammation and altering the immune system’s activity. Idacio is effective in managing diseases like rheumatoid arthritis, psoriatic arthritis, and Crohn’s disease.
Idacio works by targeting and neutralizing TNF-alpha, a protein in the immune system that causes inflammation. By inhibiting this protein, Idacio reduces the inflammatory response, which is beneficial in treating autoimmune diseases where the body’s immune system mistakenly attacks its own tissues.
Idacio is used to treat several autoimmune conditions, including rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, ulcerative colitis, and plaque psoriasis.
Idacio is administered through subcutaneous injection. Patients or caregivers can inject Idacio after proper training in subcutaneous injection techniques. The injection site should be rotated each time to reduce injury under the skin.
Common side effects include infections (e.g., upper respiratory, sinusitis), injection site reactions, headache, and rash. These side effects can vary in intensity and should be monitored closely.

The safety of Idacio during pregnancy isn’t well established. It should be used only if the potential benefit justifies the potential risk to the fetus. Women of childbearing age should discuss the risks and benefits with their healthcare provider.
There is limited information on Idacio’s impact on fertility. Patients concerned about fertility should discuss this with their healthcare provider.
Idacio should be stored in the refrigerator, protected from light and moisture. It should not be frozen. The medication can be allowed to reach room temperature for 15 to 30 minutes before injection but should not be heated or re-refrigerated.
The safety and effectiveness of Idacio in children under 2 years of age have not been established. For certain conditions like juvenile idiopathic arthritis, it has been used in children 2 years and older.
There are no specific dietary restrictions while taking Idacio, but maintaining a balanced diet can support overall health. Patients should stay hydrated and avoid foods that may irritate the mouth if experiencing mouth sores.
If you miss a dose of Idacio, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.
Idacio can interact with various medications, including live vaccines and certain cancer treatments. Patients should inform their healthcare provider about all medications, supplements, and herbal products they are taking.
While taking Idacio, patients should be cautious about potential infections and bleeding risks. Regular blood tests are required to monitor blood cell counts. Patients should avoid contact with people who have contagious infections.
Yes, Idacio can cause allergic reactions, which may manifest as skin rash, itching, hives, swelling of the face, lips, tongue, or throat, and difficulty breathing. If you experience these symptoms, seek immediate medical attention.
Alcohol consumption should generally be limited or avoided while taking Idacio, as it can interact with the medication and exacerbate side effects. Discuss alcohol use with your healthcare provider.

The time it takes for Idacio to show its effects can vary. Some patients may notice improvements within a few weeks, while for others, it may take several months. Consistent use as prescribed by a healthcare provider is important for effectiveness.
Mood changes or depression are not commonly reported side effects of Idacio. However, if you experience significant mood changes or symptoms of depression, discuss this with your healthcare provider.

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

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Price Match Guarantee

Price Match Guarantee

We are committed to providing fair, competitive pricing on all medications. If you find a lower price on the same product at another verified Canadian online pharmacy, we’ll match it.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online pharmacy with a verifiable address.
  • The competitor’s price must be current and active (not from a past or future promotion).
  • The product must be identical in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be submitted before placing an order — adjustments cannot be made after purchase.
  • Price matching does not apply to used or expired products.
  • Requests can be submitted via live chat or phone prior to completing your order.

Note: Price matching does not currently apply to Mounjaro® , Ozempic® or Saxenda®. However, this policy may be updated in the future.

Kenneth Fill, PharmD, MBA Fill

Kenneth Fill, PharmD, MBA, is a clinical pharmacist specialist and medical writer with a strong background in ambulatory care, pharmacogenomics, and medical content development. Based in the state of Michigan, he provides expert guidance on chronic disease state management. Kenneth completed his PharmD and MBA at the University of Toledo and pursued post-graduate residency training in ambulatory care and community-based pharmacy. His diverse background also includes academic detailing, clinical education, and interdisciplinary collaboration to enhance patient outcomes.