What is Imuran?
Imuran (azathioprine) is a medication that helps lower inflammation in the body. Doctors use it to treat conditions like rheumatoid arthritis and other autoimmune diseases.
Azathioprine, the main ingredient of Imuran, targets certain blood cells that cause inflammation. This makes it easier for people with autoimmune diseases to feel better and manage their symptoms.
Imuran may take several weeks to start working. Some people may also notice Imuran withdrawal symptoms if they suddenly stop taking it.
How Does Imuran Work?
Imuran works by weakening the immune system to help control inflammation. After you take it orally, your body absorbs it and converts it into active substances.
These substances enter your cells and reduce the activity of certain immune cells that trigger inflammation and tissue damage.
This helps reduce pain, swelling, and other symptoms linked to autoimmune conditions.
Imuran Dose and Administration
Doctors use Imuran to manage autoimmune conditions and support organ transplants. The Imuran dose depends on the condition being treated, the patient’s weight, and how well the body processes the drug.
Doctors often adjust the dose over time.
People with TPMT or NUDT15 deficiencies may need a lower dose to avoid side effects. The Imuran route of administration is oral, and patients usually take it once or twice a day.
Dosage Form and Strengths of Imuran
Imuran comes in tablet form and is taken by mouth. Each tablet contains 50 mg of azathioprine.
Doctors typically start with a low dose and gradually increase it based on the patient’s response and tolerance.
| Condition Treated | Typical Starting Dose | Maintenance Dose |
| Rheumatoid arthritis | 1 mg/kg daily (50 – 100 mg) | Up to 2.5 mg/kg daily |
| Renal transplant | 3 – 5 mg/kg daily (starting day of surgery) | 1 – 3 mg/kg daily |
| TPMT or NUDT15 deficiency | Lower than standard doses | Adjusted as needed to avoid toxicity |
How to Take Imuran?
- Take Imuran by mouth with a full glass of water.
- Take it with food to avoid stomach upset.
- Swallow the tablet whole; do not break, crush, or chew it.
- Follow your doctor’s instructions about how much to take.
- Do not change your dose unless your doctor tells you to.
- Get regular blood tests to check for side effects.
- If you miss a dose, take it as soon as you remember, unless it is almost time for the next dose.
Side Effects of Imuran
The side effects of Imuran can depend on your dose, how long you take it, and your overall health. It is important to report any unusual symptoms to your doctor right away. Serious Imuran adverse effects may need changes in treatment or medical care.
Common Side Effects
- Nausea or vomiting
- Loss of appetite
- Mild fever
- Tiredness
- Skin rash
- Joint pain
- Hair thinning or hair loss
- Diarrhea
- Muscle aches
Severe Side Effects
- Low white blood cell count (increased infection risk)
- Low platelet count (easy bruising or bleeding)
- Severe infections
- Liver problems (elevated liver enzymes or liver damage)
- Pancreatitis (pain in the upper belly with vomiting)
- Allergic reaction (fever, chills, body pain)
- Hepatotoxicity or liver failure
- Lung problems (cough, breathing issues)
- Increased risk of certain cancers (like lymphoma)
- Rare blood disorders
Imuran Warnings and Precautions
- Do not take Imuran if you are allergic to it.
- Do not use Imuran to treat rheumatoid arthritis if you are pregnant.
- Avoid Imuran if you have been treated with certain cancer drugs like cyclophosphamide or chlorambucil.
- Imuran may increase your risk of cancer, especially skin cancer and lymphoma.
- Protect your skin from the sun by using sunscreen and wearing protective clothing.
- If you had a kidney transplant, you may be at higher risk of getting cancer from taking Imuran.
- People with rheumatoid arthritis may also have a slightly higher risk of certain cancers.
- Some patients with Crohn’s disease or ulcerative colitis developed a rare and aggressive type of lymphoma after using Imuran.
- Imuran can lower the levels of white blood cells, red blood cells, and platelets, which may increase the risk of serious infections or bleeding.
- You may need regular blood tests to check your blood counts while taking Imuran.
- If your blood count drops too low, your doctor may reduce your dose or temporarily stop treatment.
- People with low TPMT or NUDT15 enzyme activity are more likely to get severe blood-related side effects.
- Your doctor may test you for TPMT and NUDT15 before or during treatment.
- Imuran can increase the risk of serious infections, including bacterial, viral, and fungal infections.
- Some patients have developed a rare brain infection called PML while using Imuran.
- Tell your doctor if you have new nerve symptoms like weakness, vision changes, or confusion.
- Imuran may cause temporary problems with sperm production in men.
- Imuran can harm an unborn baby. Do not take it while pregnant unless your doctor says it is necessary.
- Stop using Imuran if you develop liver problems or symptoms like yellow skin, dark urine, or itchy skin during pregnancy.
- Imuran may cause congenital disabilities in babies if either parent uses it.
- Women should avoid getting pregnant while using Imuran.
- Some babies born to mothers taking Imuran had low immune cell counts or other health issues.
- Stop taking Imuran if you get stomach pain, vomiting, or a rash soon after starting it.
- Always tell your doctor if you bleed easily or feel unusually tired or sick.
- Your doctor will give you clear instructions on how to take Imuran, especially if you have kidney problems or take other drugs.
- Imuran may affect fertility and may cause cancer.
- Imuran is not recommended for breastfeeding mothers.
- Imuran passes into breast milk and may affect your baby.
- The safety of Imuran in children is not known.
Imuran Drug Interactions
- Allopurinol
- Febuxostat
- Sulphasalazine
- Mesalazine
- Olsalazine
- Co-trimoxazole
- Angiotensin-converting enzyme (ACE) inhibitors
- Warfarin
- Ribavirin
Alternatives to Imuran
- Saphnelo (anifrolumab)
- Plaquenil (hydroxychloroquine)
- Benlysta (belimumab)
- CellCept (mycophenolate mofetil)
- Prednisone
Buy Imuran Online from Canada
You can purchase Imuran online from Canada through Pharma Giant and receive the medical care you require without overpaying.
Many Americans are concerned about the escalating costs of treatments such as Imuran, but Pharma Giant provides an easy and reasonable solution.
We collaborate with approved Canadian pharmacies to get you a lower Imuran price that is within your budget.
You may also apply an Imuran coupon or receive a 3-month supply to save even more money and enjoy added convenience.
Every order is doctor-approved and pharmacist-verified, ensuring it is safe and dependable.
How to Order Imuran Online?
- Search for Imuran on the website, choose the strength you need, and click Buy to add it to your cart.
- Enter your name, shipping address, and payment details at checkout. Use code PGSAVE10 to get 10% off your first orde.r
- Submit your prescription by uploading it, emailing info@pharmagiant.com, or faxing it to 1-888-562-8159.
Frequently Asked Questions
Disclaimer
Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.
| Have a prescription?
Order Imuran online today and enjoy a host of benefits, including: |
 |
