What is Lotrel?
Lotrel (amlodipine / benazepril) is a medication for high blood pressure. When blood pushes too hard against the walls of your blood vessels, it causes high blood pressure, also called hypertension. If you do not control it, high blood pressure can lead to heart problems, strokes, or kidney damage.
Doctors usually prescribe Lotrel after other treatments have failed to lower your blood pressure.
You can get Lotrel as a brand or as the generic of Lotrel. The generic version contains the same ingredients and works in the same way, but it usually costs less.
Do not give Lotrel to children. Before you start taking it, tell your doctor if you are pregnant, breastfeeding, or have health problems like kidney or liver disease.
Inform your doctor about all other medications, treatments, or supplements you are taking. Some may not work well with Lotrel and could cause side effects.
How Does Lotrel Work?
Lotrel helps relax your blood vessels, allowing blood to flow more easily and your blood pressure to decrease.
Lotrel combines two active ingredients: amlodipine besylate and benazepril hydrochloride. Amlodipine acts as a calcium channel blocker. It relaxes and widens your blood vessels.
Benazepril acts as an ACE inhibitor. It helps prevent the body from producing a chemical that constricts blood vessels.
Lotrel Dose and Administration
Doctors usually begin treatment with the Lotrel starting dose of 2.5 mg amlodipine and 10 mg benazepril once daily.
If blood pressure stays high, the doctor may slowly increase the dose based on your response.
The Lotrel max dose is 10 mg amlodipine and 40 mg benazepril once daily. Each person may need a different dose depending on how well the treatment works.
Dosage Form and Strengths of Lotrel
Lotrel capsules come in different strengths. Each capsule contains a specific amount of amlodipine and benazepril:
- 2.5 mg amlodipine / 10 mg benazepril
- 5 mg amlodipine / 10 mg benazepril
- 5 mg amlodipine / 20 mg benazepril
- 5 mg amlodipine / 40 mg benazepril
- 10 mg amlodipine / 20 mg benazepril
- 10 mg amlodipine / 40 mg benazepril
How to Take Lotrel?
- Take Lotrel once a day, at the same time each day
- Swallow the capsule whole, with or without food
- If a dose is missed and less than 12 hours have passed, take it right away
- If more than 12 hours have passed, skip the missed dose and take the next one at the usual time
- Do not take two doses at once
- If too much is taken, contact a doctor or go to the emergency room
- Tell your doctor or dentist that you take Lotrel before surgery, allergy treatment, or dialysis
Lotrel Dose by Condition or Population
Adults with High Blood Pressure
Most adults start with the Lotrel starting dose of 2.5 mg and 10 mg, taken once daily. If blood pressure does not decrease enough, the doctor may increase the dose. The goal is to control blood pressure using the lowest effective dose.
Seniors Age 65 and Older
Older adults often begin with the lowest dose of Lotrel. This helps reduce the chance of side effects, as the body may process the treatment more slowly. The doctor may adjust the dose based on the patient’s response.
People with Liver Problems
If you have liver problems, the doctor will likely begin with the lowest dose of Lotrel. This helps prevent too much buildup of the drug in your body.
People with Kidney Problems
People with mild or moderate kidney issues can usually take standard doses of Lotrel. If you have severe kidney disease, your doctor may choose a different treatment.
Lotrel Side Effects
Lotrel can cause both common and serious side effects. Some people may feel dizzy or develop a dry cough, while others may notice swelling in their feet or hands.
Sometimes, Lotrel side effects can include serious problems like low blood pressure, liver issues, or allergic reactions that affect breathing. There are signs of both common and severe reactions, especially if you are taking Lotrel long-term.
Common Side Effects
- Dizziness or lightheadedness
- Fainting when standing up
- Dry cough that may get worse at night
- Swelling in the feet, ankles, or hands
- Feeling tired or weak
Severe Side Effects
- Swelling of the face, lips, tongue, or throat
- Trouble breathing or wheezing
- Chest pain that gets worse or does not go away
- Yellow skin or eyes
- Pain in the upper right side of the stomach
- Nausea or flu-like symptoms
- Itching or skin rash
- Low blood pressure, especially when using water pills or a low salt diet
- Kidney problems, such as swelling or sudden weight gain
Warnings and Precautions for Lotrel
Lotrel may cause serious problems in some people. It can affect the heart, liver, and kidneys, and may lead to allergic reactions.
Some risks increase if you are pregnant, have certain health conditions, or take other treatments at the same time.
- Do not take Lotrel with other drugs like aliskiren or ARBs if you have diabetes.
- Do not take Lotrel if you have ever had swelling in the face or throat known as angioedema.
- Do not take Lotrel if you are allergic to amlodipine, benazepril, or any part of the capsule.
- Do not use Lotrel within thirty-six hours of taking a neprilysin blocker like sacubitril.
- Lotrel can harm an unborn baby and cause kidney failure, bone problems, or even death if taken during pregnancy.
- Lotrel can cause swelling of the face, lips, tongue, or throat and make it hard to breathe, which may be life-threatening.
- Lotrel may cause stomach swelling, which can lead to pain, even without signs of facial swelling.
- Lotrel may trigger strong allergic reactions during wasp sting treatment or dialysis.
- Lotrel may cause chest pain or a heart attack when starting or raising the dose, especially if you have heart disease.
- Lotrel may lower blood pressure too much and cause fainting or kidney problems, especially if you are on water pills or have been sick.
- Lotrel may reduce kidney function in people with heart failure, low blood flow to the kidneys, or those taking certain painkillers.
- Lotrel may increase potassium levels, which can lead to heart rhythm problems, especially in people with kidney disease or diabetes.
- Lotrel may cause liver problems such as yellow skin or eyes and, in rare cases, liver failure.
- If you are older, your body may take longer to clear Lotrel, and you may need a lower dose.
- Do not take Lotrel if you are breastfeeding without asking your doctor.
- Lotrel is not for children under eighteen because it has not been studied in that age group.
Lotrel Drug Interactions
Lotrel drug interactions can happen when you take Lotrel with other drugs, supplements, or herbs. These interactions can change how Lotrel works or increase the risk of side effects.
Some interactions may raise potassium levels, lower blood pressure too much, or affect kidney function.
Inform your doctor about everything you take to avoid problems with Lotrel drug interactions.
- sacubitril
- spironolactone
- eplerenone
- amiloride
- triamterene
- lithium
- simvastatin
- insulin
- metformi
- glimepiride
- pioglitazone
- sitagliptin
- injectable gold
- temsirolimus
- sirolimus
- everolimus
- ibuprofen
- naproxen
- indomethacin
- celecoxib
Alternative Medications to Lotrel
Lotrel helps lower high blood pressure, but it may not be the right option for everyone. If you need a different treatment, there are other drugs that work in similar ways.
These alternatives can help relax blood vessels, slow the heart rate, or reduce fluid buildup.
Below are some common alternatives, along with their ingredients.
- Norvasc (amlodipine)
- Zestril (lisinopril)
- Cozaar (losartan)
- Diovan (valsartan)
- Toprol XL (metoprolol succinate)
- Tenormin (atenolol)
- Coreg (carvedilol)
- Microzide (hydrochlorothiazide)
- Exforge (amlodipine and valsartan)
- Hyzaar (losartan and hydrochlorothiazide)
- Benicar (olmesartan)
- Tekturna (aliskiren)
Buy Quality Lotrel Online from Canada
You can buy Lotrel online from Canada at a lower price without compromising on safety or quality.
With Pharma Giant, you can order from home and get fast, reliable shipping right to your door. Every order follows strict quality checks and comes from licensed pharmacies.
Benefits of choosing Pharma Giant:
- Get Lotrel at lower prices compared to local US pharmacies
- Order safely from licensed Canadian pharmacies
- Receive fast and secure shipping within the US
- Buy a 3-month supply at a reduced overall cost
- See your full cost upfront with no hidden charges
- Have your prescription verified by a US doctor and a Canadian pharmacist
How to Order Lotrel Online?
- Search for Lotrel, choose your strength, and click Buy.
- Enter your name, address, and payment details at checkout. Use PGSAVE10 to get a 10% discount for your first purchase.
- Upload your prescription, email it to info@pharmagiant.com, or fax it to 1-888-562-8159.
Frequently Asked Questions
Disclaimer
Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.
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