What is Lynparza (olaparib)?
Lynparza (olaparib) treats certain types of cancer for adults with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer.
These cancers affect the female reproductive system and the lining of the abdomen. Lynparza is used as maintenance treatment, which means it helps keep the cancer from coming back after initial treatment with chemotherapy.
For prostate cancer, Lynparza may be administered alone or with other medications. Patients who take Lynparza should have a test to check if their cancer has the right gene changes for the treatment to work.
Lynparza medication may cause side effects like nausea, tiredness, and low blood cell counts. Doctors monitor patients during treatment to ensure their safety.
Before starting treatment, people taking Lynparza should talk to their doctor about any health problems, pregnancy, or other medications.
How Does Lynparza Work?
Lynparza prevents cancer cells from repairing themselves when they become damaged. PARP enzymes help repair DNA in the body, which serves as the instruction guide for cells.
Cancer cells rely on these enzymes to survive and grow. Lynparza blocks PARP enzymes, making it difficult for cancer cells to repair their DNA. As the damage accumulates, the cancer cells die.
This treatment is most effective in certain cancers that already have difficulty repairing DNA, such as those with BRCA1 or BRCA2 gene mutations.
Dosage Information and Usage
The usual Lynparza dose is 300 mg twice daily, with or without food. Patients should follow their doctor’s instructions carefully to ensure the best results.
Dosage Form and Strengths of Lynparza
Lynparza comes in tablet form and is available in two strengths:
- 150 mg tablets: Green to green-grey, oval, film-coated, with “OP150” debossed on one side.
- 100 mg tablets: Yellow to dark yellow, oval, film-coated, with “OP100” debossed on one side.
How to Take Lynparza?
Taking Lynparza the right way is important for its effectiveness and safety. Here are the simple steps to follow when taking Lynparza:
- Take Lynparza as prescribed by your doctor.
- Swallow the tablets whole with water; do not chew, crush, or dissolve them.
- Take two doses per day, about 12 hours apart.
- You can take it with or without food.
- If you are using Lynparza for early breast cancer, continue your hormonal therapy during treatment.
- If you are using Lynparza for prostate cancer, continue your GnRH therapy unless advised otherwise.
- If you miss a dose, take the next dose at the usual time. Do not take an extra dose to make up for the missed one.
- If you take too much Lynparza, seek medical help immediately.
Lynparza Side Effects
Lynparza side effects can range from mild to severe, including nausea, tiredness, low blood cell counts, diarrhea, and loss of appetite.
In more serious cases, it can cause severe anemia, serious infections, lung inflammation, and bone marrow problems.
Below is a list of common and severe side effects.
Common Side Effects
- Nausea or vomiting
- Tiredness or weakness
- Low red blood cell counts
- Diarrhea
- Loss of appetite
- Headache
- Changes in the way food tastes
- Cough
- Low white blood cell counts
- Shortness of breath
- Dizziness
- Indigestion or heartburn
- Low platelet counts
Severe Side Effects
- Severe anemia (very low red blood cell counts)
- Serious infections due to low white blood cell counts
- Lung inflammation (pneumonitis), causing difficulty breathing or persistent cough
- Bone marrow problems, including myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML)
- Liver problems leading to yellowing of the skin or eyes
- Severe allergic reactions such as rash, swelling, or difficulty breathing
Warnings and Precautions
Lynparza can cause serious health problems. Some people who take it develop blood disorders like myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), which affect blood cells. Others may have lung inflammation or blood clots.
Tell your doctor immediately if you have trouble breathing, severe fatigue, unusual bruising, or leg swelling.
Pregnant women should not take Lynparza because it can harm the baby.
- Lynparza can cause MDS or AML, which are serious blood disorders.
- Watch for symptoms like fatigue, fever, easy bruising, or frequent infections.
- Lynparza may cause lung inflammation (pneumonitis), leading to cough or breathing problems.
- Blood clots can occur, including deep vein thrombosis (DVT) and pulmonary embolism (PE).
- Symptoms of blood clots include chest pain, shortness of breath, or swelling in the legs.
- Do not take Lynparza if you are pregnant, as it can harm the baby.
- Women should use birth control during treatment and for six months after stopping Lynparza.
- Men should use birth control while on Lynparza and for three months after stopping.
- Monitor blood cell counts regularly to check for serious blood problems.
- If blood tests show low counts, treatment may need to be paused or stopped.
- If lung inflammation is suspected, Lynparza should be stopped immediately.
- If you develop symptoms of a blood clot, seek medical attention right away.
Drug Interactions With Other Medications
It is important to know how Lynparza may interact with other treatments. These interactions can change how Lynparza works or cause more side effects.
- Using with other cancer treatments: Taking Lynparza with other cancer treatments that affect blood cells can make the side effects worse.
- CYP3A inhibitors: Some treatments can stop Lynparza from breaking down in the body, causing it to build up and increase side effects. Avoid using these treatments with Lynparza. If needed, your doctor may lower the Lynparza dose.
- CYP3A inducers: Some treatments can make Lynparza less effective by lowering its levels in the body. It is best to avoid using these treatments with Lynparza.
Alternatives to Lynparza
Several alternative treatments are available if you are exploring options other than Lynparza.
These alternatives to Lynparza work in different ways to help manage cancer.
Consult your doctor before choosing alternative treatments.
Order Lynparza from Canada & SAVE
At Pharma Giant, you should not have to choose between getting the treatment you need and managing your expenses.
By partnering with licensed Canadian pharmacies, Pharma Giant offers Lynparza at up to 90% lower prices than those sold in the United States. You can rest assured that you are getting the same quality treatment without the high cost.
We ensure you know the full price upfront so there are no surprises regarding Lynparza’s price.
We also offer bulk pricing, allowing you to get up to a three-month supply of Lynparza at an even better overall cost. You can save even more by joining our Customer Referral Program or signing up for our newsletter for exclusive deals.
When you choose Pharma Giant, you are choosing a trusted service. We are here to make sure you get the Lynparza you need without the stress of high costs.
How to Order Lynparza Online?
- To order Lynparza, use the search bar at the top of the website to find it. Select the strength you need on the product page and click “Buy” to add it to your cart. If you need other treatments, continue adding them before proceeding to checkout.
- At checkout, enter your contact, payment, and shipping details. New customers can create an account using an email and password, while returning customers can log in. Use the coupon code PGSAVE10 to get 10% off your first order. Once all details are entered, submit your order, and a confirmation email will be sent to you.
- Upload or send your prescription. You can upload it directly after placing your order, email a scanned copy to info@pharmagiant.com, or fax it to 1-888-562-8159. If no prescription is required, your order will be processed right away. Our team will assist you if a prescription is needed and not received.
Frequently Asked Questions
Disclaimer
Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.
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