Myrbetriq (Mirabegron)
Myrbetriq
Mirabegron
Select product strength & quantity:
Select product strength & quantity:

Myrbetriq (mirabegron)

What is Myrbetriq (mirabegron)?

Myrbetriq is a medication prescribed to treat overactive bladder symptoms such as frequent urination in adult patients.

Myrbetriq belongs to the drug class, beta-3 adrenergic agonists. This medication works by relaxing the muscle around your bladder allowing it to hold more urine.

What are the Indications for Myrbetriq?

Myrbetriq may be prescribed with another medication to treat the symptoms of overactive bladder. Symptoms of overactive bladder include urgent or frequent urination and urinary incontinence.

Myrbetriq may also be prescribed to treat neurogenic detrusor overactivity (NDO) in pediatric patients 3 years or older. Neurogenic detrusor overactivity (NDO) occurs in patients with conditions such as spina bifida, spinal cord injuries, and multiple sclerosis (MS).

Myrbetriq is not recommended:

  • If you are allergic to Myrbetriq or any ingredients in Myrbetriq
  • If you have severe kidney disease or failure
  • If you have severe uncontrolled high blood pressure

How is Myrbetriq used?

Storage

Myrbetriq tablets should be stored at room temperature between 68°F and 77°F (20°C – 25°C).

Myrbetriq granules reconstituted should be stored at room temperature for up to 28 days. After 28 days, discard any unused portion.

Keep out of reach of children.

Instructions

Take Myrbetriq by mouth once daily, as directed by your doctor, with or without food.  Pediatric patients should take Myrbetriq with food. Do not chew or crush the extended-release tablet.

Dosage

Myrbetriq is available as:

  • Extended-release tablets: 25 mg and 50 mg
  • Granules/ oral suspension: 8 mg/mL after reconstitution

Do not change your dosage and take more than what is prescribed without consulting with your doctor. If you took more than prescribed, contact your doctor or seek emergency medical care right away.

Overactive bladder

The recommended dose is 25 mg by mouth once daily. Myrbetriq may be used with solifenacin succinate 5 mg. Your doctor may increase your dose after 4-8 weeks to 50 mg once daily.

Neurogenic detrusor overactivity (NDO)

The recommended starting dose for patients 3 years or older may be dependent on weight.

  • Less than 35 kg: Myrbetriq granules will be prescribed and administered based on the patient’s weight. The dose may be increased after 4-8 weeks.
  • 35 kg or more: the patient can be prescribed Myrbetriq 25 mg tablet or Myrbetriq granules 6 mL once daily. The dose may be increased after 4-8 weeks.

Side Effects

It’s important to understand that although Myrbetiq is FDA approved, it comes with side effects that may or may not affect you.

Before starting Myrbetiq, you should discuss possible side effects with your doctor or pharmacist.

Common Side Effects

Not all side effects require medical attention. As your body adjusts to Levitra, side effects may go away.

Tell your doctor if you experience the following symptoms, and they become severe or do not go away on their own:

  • Sinus pain
  • Sore throat
  • Headache
  • Constipation
  • Painful urination
  • Dry mouth
  • Fast heartbeats

Serious Side Effects

Severe adverse reactions while taking Myrbetiq can occur. Seek emergency medical care or call 911 if you experience any of the following symptoms:

  • Severe allergic reaction: severe rash or itching, swelling in the face, lips, tongue, or throat, rapid heartbeat, fainting or dizziness, or problems breathing or swallowing.
  • High blood pressure: blurred vision, pounding in ears or neck, severe headache.
  • Pain or burning during urination
  • Unable to empty your bladder

The information above does not list all possible side effects. Contact your doctor or pharmacist if you experience any side effects not listed. You or your doctor may report side effects to the FDA by calling 1-800-FDA-1088.

Warnings & Precautions

Before taking Myrbetiq, tell your doctor or pharmacist:

  • If you are allergic to any medications such as Myrbetiq
  • If you have or have had heart problems such as heart failure
  • If you have uncontrolled high blood pressure
  • If you have kidney problems
  • If you have liver problems

Angioedema

Taking Myrbetiq can result in the swelling of your face (e.g. lips, tongue) and larynx that can be life-threatening. If swelling occurs in your tongue or larynx, discontinue use and seek emergency medical attention.

High Blood Pressure

Taking Myrbetiq can increase blood pressure. Myrbetiq is not recommended if you have uncontrolled high blood pressure. Your doctor may recommend regular blood pressure monitoring to ensure your blood pressure is under control.

Symptoms of high blood pressure include severe headaches, nosebleeds,  fatigue, vision problems or confusion, chest pain, difficulty breathing, or irregular heartbeat.

Liver Disease

If you have moderate hepatic dysfunction, your daily should not exceed 25 mg. Studies have not been completed for patients with severe hepatic dysfunction therefore Myrbetiq is not recommended for these patients.

Kidney Disease

If you have severe renal impairment, your daily dose should not exceed 25 mg. Studies have not been completed for patients with end-stage renal disease therefore Myrbetiq is not recommended for these patients.

Urinary Retention

If you have bladder outlet obstruction (BOO) or are taking a muscarinic antagonist medication, taking Myrbetiq may result in the inability to completely empty your bladder.

Interactions & Contraindications

Before taking Myrbetiq, tell your doctor or pharmacist if you take any medications, herbal supplements, or vitamins.

Medications metabolized by CYP2D6

Taking Myrbetiq (a CYP2D6 inhibitor) in combination with medications metabolized by CYP2D6 such as antidepressants, sertraline, paroxetine, and thioridazine will increase the systemic exposure of CYP2D6. Your doctor will review and adjust your dose as needed.

Muscarinic antagonist medication

Taking Myrbetiq with muscarinic antagonist medications such as atropine, glycopyrrolate, and ipratropium bromide may cause you to be unable to completely empty your bladder. Consult with your doctor if you cannot empty your bladder to determine if your dose or therapy needs to be changed.

Oxybutynin

Taking Myrbetiq with oxybutynin may cause you to be unable to completely empty your bladder. Consult with your doctor if you cannot empty your bladder to determine if your dose or therapy needs to be changed.

Frequently Asked Questions

The active ingredient in Myrbetiq is mirabegron.

Myrbetiq tablets may contain the following inactive ingredients: butylated hydroxytoluene, hydroxypropyl cellulose, hypromellose, magnesium stearate, polyethylene glycol, polyethylene oxide, red ferric oxide (25 mg MYRBETRIQ tablet only), and yellow ferric oxide.

Myrbetiq granules may contain the following inactive ingredients: acesulfame potassium, diluted hydrochloric acid, ethylparaben, hypromellose, magnesium stearate, mannitol, methylparaben, silicon dioxide, simethicone, sodium polystyrene sulfonate, and xanthan gum.

Myrbetiq is available in tablet form and granule form to be mixed into a suspension.

Myrbetiq is approved to treat the symptoms of overactive bladder in adult patients and neurogenic detrusor overactivity (NDO) in pediatric patients 3 years or older.

Myrbetiq is approved to treat the symptoms of overactive bladder in adult patients and neurogenic detrusor overactivity (NDO) in pediatric patients 3 years or older.

An overactive bladder is a medical condition where you have a strong urge to urinate or your bladder may leak even if it isn’t full.

Myrbetiq is not recommended if you are allergic to Myrbetriq or any ingredients in Myrbetriq, have severe kidney disease or failure, or if you have severe uncontrolled high blood pressure.

Serious allergic reactions include severe rash or itching, swelling in the face, lips, tongue, or throat, rapid heartbeat, fainting or dizziness, or problems breathing or swallowing.

Take Myrbetiq by mouth, as directed, with or without food. Pediatric patients should take this medication with food. Do not crush or chew the tablet.

You may start to see improvements in your symptoms within 4-8 weeks. Results will vary with each individual.

You should not stop using Myrbetriq without consulting your doctor. You should take Myrbetriq every day as prescribed even if you are not seeing improvements in your symptoms. It can take 4-8 weeks before you see improvements.

If it has not been more than 12 hours since you missed your dose, take your missed dose immediately. If it has been more than 12 hours, skip this dose and take your next dose as scheduled.

If you took more than prescribed, contact your doctor or seek emergency medical care right away.

Yes, with a prescription, you can purchase Myrbetiq online. Buying medications online is convenient and often less expensive than purchasing at your local pharmacy.