
What is Nardil?
Nardil (phenelzine) is a treatment used when other ways to manage depression have not worked for you. It helps people who feel deeply sad, anxious, or nervous for long periods.
Before taking this medication, you must know about Nardil contraindications or reasons not to take it.
Do not take Nardil if you have liver problems, high blood pressure, or a history of seizures, strokes, or heart issues. You must also avoid certain foods and drinks because Nardil can react badly with them.
If you stop using it, you might feel Nardil withdrawal symptoms. These can include mood swings, headaches, or feeling dizzy. This is called Nardil withdrawal, and it can be hard to manage without a doctor’s help.
How Does Nardil Work?
Nardil works by helping the brain retain more chemicals that affect mood, including serotonin, dopamine, and norepinephrine.
When these levels are too low, you may feel sad, anxious, or tired for long periods. Nardil blocks a substance in your body called monoamine oxidase.
This substance typically breaks down mood chemicals. When Nardil blocks it, the serotonin, dopamine, and norepinephrine levels go up. This helps you to feel more balanced and in control of your emotions.
Nardil Dosage and Administration
Nardil comes as a 15 mg tablet that you take by mouth. You should take it exactly as your doctor tells you. Swallow the tablet with a glass of water.
Take it at the same time each day to help you remember. Do not change your Nardil dosage or stop taking it unless your doctor says it is safe.
Dosage Form and Strengths of Nardil
Nardil comes as 15 mg tablets that you take by mouth with water. You can only get Nardil with a prescription from your doctor.
The manufacturer usually provides the tablets in bottles. Store them in a cool and dry place. Keep them away from light and moisture.
How to Take Nardil?
- Take Nardil by mouth with water.
- Take it at the same time every day.
- Do not take more than your doctor tells you.
- If you miss a dose, take it as soon as you remember.
Recommended Nardil Dosage
The usual starting Nardil dose is 15 mg, taken three times daily. Your doctor may slowly increase the dose.
Many people take 60 to 90 milligrams each day to improve their well-being. They often divide this amount into smaller doses throughout the day.
The maximum Nardil dose is usually 90 mg per day. Children and older adults may need a lower dosage and closer monitoring.
If you have other health problems, your doctor will adjust the Nardil dose to make it safer.
Side Effects of Nardil
Nardil may cause different side effects, some more serious than others. Many people notice mild issues at first, such as dizziness, dry mouth, or changes in sleep.
These are common side effects and may go away as your body gets used to the Nardil dosage. However, there are also more serious side effects that need quick medical help.
These may include allergic reactions, high blood pressure, or thoughts of suicide. Knowing the possible side effects helps you stay safe and get help when needed.
Common Side Effects
- Dizziness or feeling lightheaded
- Headache
- Trouble sleeping or feeling very sleepy
- Feeling tired or weak
- Twitching or trembling
- Constipation
- Dry mouth
- Weight gain
- Low blood pressure when standing
- Swelling or fluid buildup
- Sexual problems like trouble reaching orgasm or impotence
Severe Side Effects
- Allergic reaction with swelling, rash, or trouble breathing
- Fast or irregular heartbeat
- Chest pain or pressure
- Sudden severe headache
- Blurred vision or confusion
- High blood pressure that causes anxiety, nosebleeds, or ringing in the ears
- Thoughts of suicide or major mood changes
- Signs of mania include high energy, racing thoughts, or fast talking
- Muscle twitching or stiffness
- Fever, sweating, or seeing things that are not there
- Seizures
- Fainting or extreme dizziness when standing up
If you have any severe side effects, stop taking Nardil and call your doctor right away.
Nardil Precautions
Nardil can help treat certain types of depression, but it also comes with serious warnings. Some people may feel worse in the first few weeks or notice new feelings like anxiety, restlessness, or even thoughts of self-harm.
- You should not take Nardil if you have serious heart disease, liver problems, or a history of stroke or seizures.
- You must avoid certain foods while using Nardil, including aged cheese, cured meats, sauerkraut, pickled fish, and alcohol. These can cause dangerous spikes in blood pressure.
- You need to avoid many common cold and cough treatments, allergy pills, nasal sprays, diet pills, and anything with dextromethorphan. These can interact with Nardil and cause serious side effects.
- You should talk to your doctor about all the other treatments and supplements you use. Nardil can interact with many other drugs and lead to bad reactions.
- You may feel dizzy or faint when you stand up quickly. This condition, called low blood pressure, commonly occurs with Nardil. Stand up slowly and sit down immediately if you feel lightheaded.
- If you suddenly stop taking Nardil, you may get Nardil withdrawal symptoms like mood changes, anxiety, nausea, or trouble sleeping. Your doctor will help you stop safely to avoid Nardil withdrawal.
- Nardil may increase the risk of suicidal thoughts, especially in people under 25. Tell your doctor right away if you or someone close to you notices mood changes, restlessness, or thoughts of self-harm.
- Doctors check for bipolar disorder before starting Nardil. Taking it without knowing about bipolar disorder triggers a manic episode.
- Nardil is not approved for use in children and may not be safe during pregnancy or breastfeeding. Talk to your doctor if you are pregnant, planning to get pregnant, or nursing.
- Your doctor will closely monitor you during the first few months of taking Nardil. Inform your doctor if you feel worse or notice sudden changes in your behavior.
- If you have diabetes, Nardil may change your blood sugar levels. Your doctor may need to adjust your insulin or diabetes pills.
- You should not take Nardil with drugs used for high blood pressure without careful monitoring. The combination can make your blood pressure too low.
- If you have epilepsy or a history of seizures, be very careful while using Nardil. It can change your seizure threshold and make seizures more likely.
- Nardil can cause overactive moods in people with mood disorders. Talk to your doctor if you feel unusually happy, energetic, or start doing risky things.
- If you have schizophrenia, Nardil can make your symptoms worse. Let your doctor know about any past mental health problems.
- Older adults may need lower doses of Nardil. This is because they may have slower kidney or liver function and be more sensitive to the effects.
- Never share your Nardil with anyone else. It was prescribed for your specific needs and may be harmful to others.
- If you experience a sudden headache, stiff neck, fast heartbeat, or chest pain while taking Nardil, stop using it and get medical help right away. These may be signs of a hypertensive crisis.
- If you need surgery, dental work, or emergency care, tell your care team that you are taking Nardil. This can help prevent serious drug interactions.
Nardil Drug Interactions
Nardil interactions with other drugs can be dangerous and may cause serious side effects.
Some foods and drinks can also lead to harmful reactions. Ask your doctor about every medication you take, including over-the-counter products and natural supplements.
- MAOIs like isocarboxazid, rasagiline, safinamide, selegiline, tranylcypromine
- Other drugs for depression, anxiety, mood, or mental health problems
- Prescription pain drugs
- Meperidine
- Tramadol
- Tryptophan
- SAM-e
- St. Johns Wort
- Buspirone
- Linezolid
- Methylene blue
- Cocaine
- Atomoxetine
- Viloxazine
- Procarbazine
- Cyclobenzaprine
- Carbamazepine
- Phenothiazines like chlorpromazine, prochlorperazine, thioridazine
- Barbiturates like phenobarbital
- General or local anesthetics
- Medications for migraine headaches
- Medications for Parkinsons disease like entacapone, levodopa, selegiline, tolcapone
- Diet pills or stimulants like amphetamines or ephedra
- Caffeine
- Ginseng
- Green tea
- Guarana
- Dextromethorphan
- Diphenoxylate
- Ephedrine
- Yohimbine
- Tyramine in foods like aged cheese, red wine, beer, and chocolate
- Certain drugs for blood pressure like guanabenz, guanadrel, guanethidine, or reserpine
- Diuretic
- Isoniazid
- Drugs for diabetes
- Drugs for allergies, cold, flu, sinus problems, or breathing trouble
Alternative Medications to Nardil
If Nardil is not the right option for you, consider other treatments that may help with depression. Some work differently in the brain or have fewer restrictions with food and drug interactions.
Your doctor will choose the best option based on your symptoms, health history, and past responses to other treatments.
Below are some common alternatives to Nardil to explore.
Buy Nardil Online and SAVE
Paying for Nardil should not be stressful. But for many people, high drug prices in the United States make it hard to afford the treatment they need.
If you have been skipping doses or delaying refills because of the cost, you are not alone. We understand how frustrating this can be, and we are here to offer a better option that puts your health first.
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How to Order Nardil Online?
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- Upload your prescription, or send it by email to info@pharmagiant.com or by fax to 1-888-562-8159.
Frequently Asked Questions
Disclaimer
Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.





