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Novolin GE 30 / 70 Penfill Cartridge Insulin Injection, Insulin Isophane Human Biosynthetic
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What are Novolin GE 30/70 Penfill Cartridges?

Novolin GE 30/70 Penfill Cartridges (insulin premixed 30/70) are used for people with diabetes to help control high blood sugar levels.

This type of insulin is a mix of two kinds: insulin isophane and regular human insulin. Insulin isophane helps keep blood sugar levels steady for a longer time, while regular insulin works quickly to lower blood sugar right after meals.

Novolin GE 30/70 is made using a special process with yeast to create insulin that is just like the insulin naturally found in the body.

The cartridge contains this insulin mixed with other ingredients like zinc chloride and glycerol, which help keep the insulin effective.

Before using a Novolin GE 30/70 Penfill Cartridge, make sure it’s the right type of insulin and check the cartridge for any damage. Always use a new needle for each injection to prevent infections, and never share your insulin device or needles with others.

Also, don’t refill the cartridge; use it with Novo Nordisk insulin delivery devices and keep a spare syringe and extra insulin on hand just in case.

How Does Novolin GE 30/70 Penfill Cartridges Work?

Novolin GE 30/70 Penfill Cartridges work by helping to lower blood sugar levels in people with diabetes.

This insulin is a mix of two types: one that acts quickly and one that works more slowly. The fast-acting insulin helps lower blood sugar right after meals, while the slower-acting insulin keeps blood sugar levels steady over a longer period.

By injecting this insulin, you can better manage your blood sugar levels throughout the day and night, which is important for controlling diabetes and staying healthy.

Dosage Information and Usage

Dosage Form and Strengths of Novolin GE 30/70 Penfill Cartridges

Novolin GE 30/70 is available in Penfill cartridges, each containing 3 mL of insulin. This insulin is a mix of two types: 30% rapid-acting insulin and 70% longer-acting insulin, which helps manage blood sugar levels in people with diabetes.

Usage

Prepare the Cartridge:

  • Roll the Cartridge: Before using, gently roll the cartridge between your palms 10 times to mix the insulin. Make sure the cartridge stays horizontal.
  • Mix the Insulin: Move the cartridge up and down 10 times to help mix the insulin until the liquid looks uniformly white and cloudy.

Check the Cartridge:

  • Inspect for Damage: Check the cartridge and rubber stopper for any damage. Do not use it if you see any issues or if there is a gap between the stopper and the barcode label.

Prepare for Injection:

  • Attach a New Needle: Always use a new needle for each injection to avoid contamination.
  • Fill the Needle: Insert the needle into the cartridge and draw the required dose of insulin.

Inject the Insulin:

  • Choose an Injection Site: Inject the insulin under the skin using the technique recommended by your healthcare provider.
  • Administer the Dose: Keep the needle under the skin for at least 6 seconds to ensure the full dose is delivered.
  • Remove the Needle: After injection, remove the needle and discard it. Store the cartridge without the needle attached to prevent leakage.

Additional Tips:

  • Check Insulin Levels: Ensure there are at least 12 units of insulin in the cartridge before use to allow for proper mixing.
  • Carry a Spare: Keep a spare syringe and extra insulin with you in case the device is lost or damaged.

Storage Information

Keep Novolin GE 30/70 Penfill Cartridges in the refrigerator when they are not in use. Store them at a temperature between 2°C and 10°C, but avoid placing them in or near the freezer or cooling elements.

It’s important to keep the cartridges in their original carton to protect them. Do not freeze the insulin, as freezing can damage it and make it ineffective.

Side Effects of Novolin GE 30/70 Penfill Cartridges

Common Side Effects

  • Redness, itching, or swelling at the injection site
  • Low blood sugar (hypoglycemia) which may cause:
  • Anxiety
  • Dizziness
  • Sweating
  • Headache
  • Hunger
  • Trembling

Serious but Rare Side Effects

  • Signs of allergy:
    • Hives
    • Rash
    • Severe reactions like swelling of the face or throat, difficulty breathing, or wheezing.
  • Changes at the injection site (Lipodystrophy):
    • Skin thickening or pitting
    • Affects insulin absorption
  • Diabetic retinopathy (worsening of eye conditions with rapid changes in blood glucose)
  • Painful neuropathy (nerve pain or discomfort)
  • Swollen joints (water retention causing swelling around ankles and other joint)
  • Vision problems (temporary disturbances in vision at the start of treatment)
  • Lumps under the skin (rare formation of lumps due to amyloid deposits)

Warnings and Precautions

  • Hypoglycemia Risk: Low blood sugar is a common side effect of insulin. Symptoms can include shakiness, confusion, and dizziness. Always monitor your blood glucose levels and be prepared to treat hypoglycemia quickly.
  • Severe Reactions: If not treated, low or high blood sugar can lead to unconsciousness, coma, or death. Seek immediate medical help if you experience severe symptoms.
  • Glucose Monitoring: Regular blood glucose testing is essential to manage your diabetes effectively. Follow your doctor’s recommendations for testing frequency.
  • Insulin Changes: Adjustments to your insulin dosage should only be made under medical supervision to avoid complications.
  • Not for Pumps or IV Use: Novolin GE 30/70 Penfill Cartridges are not suitable for insulin pumps or intravenous administration.
  • Check Insulin Appearance: Ensure the insulin is uniformly white and cloudy. Do not use it if it looks lumpy, or grainy, or if it remains clear after shaking.
  • Allergic Reactions: Watch for signs of serious allergic reactions like swelling of the face or throat, difficulty breathing, or severe rash. Seek immediate medical help if these occur.
  • Injection Site Care: Rotate injection sites to prevent changes in the skin such as thickening or pitting. This helps maintain proper insulin absorption and reduces skin issues.
  • Insulin Requirements: Your insulin needs can change due to various factors like illness, stress, or changes in diet and exercise. Inform your doctor of any significant changes in your health.
  • Diabetes Identification: Wear a medical ID bracelet or carry a card indicating that you have diabetes and are using insulin.
  • Driving and Machinery: Low blood sugar can impair your ability to drive or operate machinery. Avoid these activities if you experience symptoms of low blood sugar.
  • Educate Others: Inform family and friends about the signs of hypoglycemia and how to use a glucagon kit if needed.
  • Low Blood Sugar Management: Always carry a quick source of sugar. Severe hypoglycemia may require glucagon or intravenous glucose.
  • Low Potassium: Insulin can lower potassium levels. Symptoms include leg cramps and tiredness. Report any unusual symptoms to your doctor promptly.
  • Pregnancy: Insulin needs may change during pregnancy. Monitor blood glucose levels closely and adjust insulin doses as needed.
  • Breastfeeding: Adjustments in insulin or diet may be necessary while breastfeeding.

Overdosage of Novolin GE 30/70 Penfill Cartridges

Taking too much Novolin GE 30/70 can lead to low blood sugar, or hypoglycemia. This may happen if you use more insulin than needed, skip meals, or exercise more than usual.

Symptoms of hypoglycemia can appear suddenly and include cold sweat, headache, rapid heartbeat, feeling very hungry, drowsiness, confusion, and difficulty concentrating.

If you notice these signs, eat glucose tablets, and sweets, or drink fruit juice immediately, then rest.

Always carry a quick source of sugar with you. Inform friends and family that if you lose consciousness, they should call for medical help right away and turn you on your side.

They should not give you food or drink to avoid choking.

Drug Interactions With Other Medications

Medications That May Increase the Risk of Hypoglycemia:

  • ACE inhibitors (e.g., ramipril, enalapril): Can lower blood sugar levels, increasing the risk of hypoglycemia.
  • Alcohol: Can cause a drop in blood sugar levels, leading to hypoglycemia.
  • Androgens (e.g., testosterone): May affect blood sugar levels, potentially requiring insulin dose adjustments.
  • Beta-blockers (e.g., atenolol, metoprolol): Can mask symptoms of hypoglycemia and affect blood sugar levels.
  • Diuretics (e.g., furosemide, hydrochlorothiazide): Can raise blood sugar levels, potentially causing hyperglycemia.
  • Disopyramide: Can lower blood sugar levels, increasing the risk of hypoglycemia.
  • Glucagon: Used to treat severe hypoglycemia and can influence insulin needs.
  • Octreotide: Can lower blood sugar levels, potentially causing hypoglycemia.
  • Salicylates (e.g., ASA): Can lower blood sugar levels, increasing the risk of hypoglycemia.
  • Sulfa antibiotics (e.g., sulfamethoxazole): Can lower blood sugar levels, increasing the risk of hypoglycemia.
  • Monoamine oxidase inhibitors (MAOIs; e.g., phenelzine): Can lower blood sugar levels, increasing the risk of hypoglycemia.
  • Quinine: Can lower blood sugar levels, increasing the risk of hypoglycemia.
  • Sulphonamides (e.g., sulfamethoxazole): Can lower blood sugar levels, increasing the risk of hypoglycemia.
  • Some hepatitis C antivirals (e.g., daclatasvir, sofosbuvir): Can affect blood sugar levels and interact with insulin therapy.

Medications That May Increase the Risk of Hyperglycemia:

  • Birth control pills: Can increase blood sugar levels, potentially requiring insulin dose adjustments.
  • Corticosteroids (e.g., prednisone, prednisolone): Can raise blood sugar levels, leading to hyperglycemia.
  • Estrogens (e.g., conjugated estrogen, estradiol): Can affect blood sugar levels, possibly requiring insulin dose adjustments.
  • Glucocorticoids (e.g., cortisone): Can raise blood sugar levels, increasing the risk of hyperglycemia.
  • HIV protease inhibitors (e.g., ritonavir, saquinavir): Can raise blood sugar levels, leading to hyperglycemia.
  • Niacin: Can increase blood sugar levels, leading to hyperglycemia.
  • Progestins (e.g., levonorgestrel): Can affect blood sugar levels, potentially causing hyperglycemia.
  • Sympathomimetics (e.g., epinephrine): Can increase blood sugar levels, leading to hyperglycemia.
  • Thyroid hormones: Can affect blood sugar levels, potentially requiring insulin dose adjustments.
  • Growth hormone: Can increase blood sugar levels, potentially causing hyperglycemia.
  • Certain diabetes medications (e.g., canagliflozin, glyburide): Can alter blood sugar levels and insulin needs.
  • Decongestants (e.g., pseudoephedrine): Can raise blood sugar levels, leading to hyperglycemia.
  • Thiazides (e.g., hydrochlorothiazide): Used to treat high blood pressure, may raise blood sugar levels.
  • Sympathomimetics (e.g., salbutamol): Used to treat asthma, may increase blood sugar levels.

Medications With Variable Effects on Blood Sugar:

  • Atypical antipsychotics (e.g., clozapine, olanzapine): Can increase blood sugar levels, leading to hyperglycemia.
  • Dabrafenib: May affect blood sugar levels, potentially altering insulin requirements.
  • Danazol: Can impact blood sugar control, possibly requiring insulin dose adjustments.
  • Exenatide: May interact with insulin and affect blood sugar control.
  • Liraglutide: May interact with insulin and affect blood sugar control.
  • Mifepristone: Can influence blood sugar levels, requiring changes in insulin dosage.
  • Pasireotide: May affect blood sugar control and require insulin dose adjustments.
  • Pentamidine: Can cause hypoglycemia and affect insulin requirements.
  • Somatostatin acetate: May influence blood sugar control and interact with insulin therapy.
  • Sunitinib: Can affect blood sugar levels, potentially requiring insulin adjustments.
  • Tacrolimus: Can raise blood sugar levels, leading to hyperglycemia.
  • Vorinostat: May impact blood sugar levels and interact with insulin therapy.
  • Other diabetes medications (e.g., metformin, glyburide): Can alter blood sugar levels and insulin needs.
  • Hepatitis C antivirals (e.g., daclatasvir, sofosbuvir): May affect blood sugar levels, requiring adjustments in insulin dosage.

Alternative Medications

Cost & Coupons

At Pharma Giant, we believe that managing your diabetes should be affordable and stress-free. Novolin GE 30/70 Penfill Cartridges are essential for regulating blood sugar, but the cost in the United States can be significantly high, with prices exceeding $150 per cartridge.

We offer a much more affordable option, ensuring you can manage your health without breaking the bank.

Affordable Options for Novolin GE 30/70 Penfill Cartridges

At Pharma Giant, we offer Novolin GE 30/70 Penfill Cartridges (100 Units/mL) at competitive prices:

Strength Quantity Price
30u/mL/70u/mL 5 cartridges $104.00
30u/mL/70u/mL 10 cartridges $168.00
30u/mL/70u/mL 15 cartridges $237.00
30u/mL/70u/mL 20 cartridges $296.00
30u/mL/70u/mL 25 cartridges $360.00

We ensure competitive pricing to help you manage your diabetes with ease and affordability.

Special Discount Offer

Promo Code: Apply PGSAVE10 at checkout to get a 10% discount on your Novolin GE 30/70 Penfill Cartridges order. This limited-time offer lets you save more on your essential medication.

Offer Details: The discount is available for one-time use per customer.

Ordering Process

  • Prescription Needed: A valid prescription is required to purchase Novolin GE 30/70 Penfill Cartridges, ensuring safe and regulated treatment.
  • Bulk Orders: You can order up to a 90-day supply, making it easier to manage your treatment long-term while saving money.

At Pharma Giant, we prioritize your health and budget, providing affordable, reliable options for managing diabetes.

Frequently Asked Questions

Novolin GE 30/70 Penfill Cartridges are used to manage blood sugar levels in adults with diabetes. They combine 30% short-acting insulin with 70% intermediate-acting insulin to help control blood sugar throughout the day.

Novolin GE 30/70 Penfill is injected under the skin using a pen device. Choose an injection site on the thigh, abdomen, or upper arm, clean the area with an alcohol swab, and insert the needle at a 90-degree angle. Press the pen button to deliver the insulin, then remove the needle and dispose of it safely.

Novolin GE 30/70 is typically injected once or twice a day. The exact frequency depends on your individual needs and your doctor’s recommendations.

Mixing Novolin GE 30/70 with other insulins is generally not recommended. It is best to use it as prescribed by your doctor.

If you miss a dose of Novolin GE 30/70, inject it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Store Novolin GE 30/70 Penfill Cartridges in the refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Once in use, it can be kept at room temperature (up to 25°C or 77°F) for up to 28 days. Keep it away from direct heat and light.

No, you should not use Novolin GE 30/70 after the expiration date. Using expired insulin may not be effective and could be harmful. Always check the expiration date and properly dispose of any expired medication.

Common side effects of Novolin GE 30/70 include:
  • Hypoglycemia: Low blood sugar, which can cause symptoms like sweating, shaking, and confusion.
  • Injection site reactions: Redness, swelling, or pain at the injection site.
  • Weight gain: Increase in body weight due to changes in metabolism.

If you experience severe low blood sugar (hypoglycemia), seek immediate medical help by calling emergency services. If you have a glucagon kit, use it according to the instructions to help raise your blood sugar levels. If you are unconscious, do not attempt to eat or drink anything, as this could lead to choking. Inform your family or friends about how they should respond in case of severe hypoglycemia. After receiving medical attention, be sure to contact your doctor to discuss and adjust your treatment plan as needed.

To inject Novolin GE 30/70 properly, follow these steps:
  • Wash Your Hands: Clean your hands thoroughly with soap and water.
  • Prepare the Injection Site: Choose a clean, dry area of skin on your abdomen or thigh. Rotate injection sites to avoid irritation.
  • Prepare the Insulin: Roll the pen gently between your hands to mix the insulin, if required. Ensure the insulin is evenly mixed.
  • Attach the Needle: If using a pen, attach a new needle according to the manufacturer’s instructions.
  • Prime the Pen: Dial a small dose and push the button to ensure insulin is flowing and remove any air bubbles.
  • Insert the Needle: Pinch the skin at the injection site, insert the needle at a 90-degree angle, and push the plunger to inject the insulin.
  • Remove the Needle: After injecting, remove the needle and dispose of it properly.
  • Check the Injection Site: Apply gentle pressure to the site with a clean cotton ball if needed, and avoid massaging the area.

If you are pregnant, you should use Novolin GE 30/70 only under the guidance of your healthcare provider. Insulin needs often change during pregnancy, and your doctor will adjust your dosage as needed to maintain proper blood glucose levels.

If Novolin GE 30/70 appears discolored, such as being pink, red, or brown, or if it contains particles or clumps, do not use it. Discolored or altered insulin may be ineffective or unsafe.

No, Novolin GE 30/70 should not be used in insulin pumps. It is also not suitable for intravenous administration.

If the cartridge seems to be empty, do not attempt to use it. Dispose of it according to your local guidelines and replace it with a new cartridge.

Yes, Novolin GE 30/70 can cause weight gain as a side effect. If you experience significant or persistent weight gain, inform your doctor or pharmacist. They can guide managing this side effect and adjust your treatment if necessary.

You can tell if Novolin GE 30/70 is working by monitoring your blood glucose levels. This insulin starts working 30 to 60 minutes after injection, peaks between 2 and 8 hours, and remains effective for about 18 to 24 hours. Regular blood sugar testing will help you see if your glucose levels are being controlled as expected.

You can drink alcohol while using Novolin GE 30/70, but it can affect your blood sugar levels and increase the risk of hypoglycemia (low blood sugar). It’s important to monitor your blood glucose closely and consult your doctor about safe alcohol consumption while on this medication.

If you accidentally take too much Novolin GE 30/70, monitor your blood sugar levels closely. Symptoms of overdose can include severe hypoglycemia, such as confusion, dizziness, or fainting. Eat or drink something with sugar immediately to raise your blood sugar.

The shelf life of Novolin GE 30/70 is typically indicated on the packaging or label. It is important to check the expiration date and not use the insulin after this date to ensure its effectiveness and safety.

To dispose of used Novolin GE 30/70 cartridges, place them in a designated sharps container or a hard, puncture-proof container. Do not throw them in the regular trash.

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

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We are committed to providing fair, competitive pricing on all medications. If you find a lower price on the same product at another verified Canadian online pharmacy, we’ll match it.

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  • The competitor’s price must be current and active (not from a past or future promotion).
  • The product must be identical in strength, pack size, quantity, manufacturer, and country of origin.
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Note: Price matching does not currently apply to Mounjaro® , Ozempic® or Saxenda®. However, this policy may be updated in the future.