What is Plendil?
Plendil (felodipine ER) is a tablet used to treat high blood pressure, also called hypertension.
Plendil focuses on lowering blood pressure to reduce the risk of serious heart problems like stroke and heart attack.
Many people with high blood pressure need more than one type of treatment to keep their numbers under control.
Plendil works well as part of a complete plan that may include eating less salt, staying active, quitting smoking, and taking other treatments if needed.
Indications and Benefits of Plendil
Plendil helps lower high blood pressure and reduces the risk of stroke and heart attack. It works by relaxing the blood vessels, allowing blood to flow more easily.
Benefits of Plendil
- Lowers high blood pressure
- Reduces risk of heart attack and stroke
- Improves blood flow by relaxing blood vessels
- Can be part of a comprehensive heart-health plan
How It Works
Plendil works by helping your blood vessels relax and widen. This makes it easier for blood to flow, which lowers high blood pressure.
Plendil contains felodipine, a type of calcium channel blocker. It blocks the flow of calcium into the muscle cells of your blood vessels.
Without calcium, these muscles do not contract as tightly, so the blood vessels remain more open. This helps reduce the pressure inside the arteries and lowers the risk of heart problems, such as stroke or heart attack.
Dosage
Plendil is taken by mouth once a day to help manage high blood pressure. The usual starting dose for most adults is 5 mg daily.
Depending on how the body responds, the dose can be lowered to 2.5 mg or increased to a maximum of 10 mg per day.
People over 65 years old or those with liver problems may need a lower dose and regular monitoring.
What Dosage Strengths Does Plendil Come In?
Plendil comes in extended-release tablets. These tablets slowly release the active ingredient, felodipine, throughout the day.
Available strengths:
- 2.5 mg tablet
- 5 mg tablet
- 10 mg tablet
Dosage Chart
| Strength | Usual Dose | Note |
| 2.5 mg | Low starting dose | For elderly or liver-impaired patients |
| 5 mg | Standard dose | Most commonly used starting dose |
| 10 mg | Maximum daily dose | Use only if lower doses do not control BP |
Usage Guide
How to take Plendil?
- Take Plendil once a day, at the same time each day
- Swallow the tablet whole with water
- Do not crush, chew, or split the tablet
- Take it on an empty stomach or with a light meal
- Follow the dose your doctor recommends
- Do not skip doses or stop taking it suddenly
- If you miss a dose, take it as soon as you remember (unless it is close to the next dose)
Side Effects
Common Side Effects:
- Swelling in the hands, legs, ankles, or feet
- Headache
- Flushing or feeling warm
- Low energy or tiredness
- Dizziness
- Constipation
- Upset stomach
- Nausea
Severe Side Effects
- Very low blood pressure (feeling faint, pale skin, dizziness)
- Chest pain or pressure
- Irregular or fast heartbeat
- Trouble breathing or shortness of breath
- Severe swelling of the face, lips, or throat
- Rash, hives, or severe skin reactions
- Unusual bleeding or bruising
- Gum swelling or overgrowth
- Vision changes
- Mood changes like depression or anxiety
Missed Dose
If you miss a dose, take it as soon as you remember (unless it is close to the next dose).
Overdose
A Plendil overdose may cause your blood pressure to drop too low and may slow down your heart rate. This can make you feel dizzy, weak, or faint. In severe cases, it may lead to serious complications.
If someone takes too much Plendil, they should lie down with their legs raised and get medical help right away.
Doctors may give fluids through a vein to help raise blood pressure. If the heart rate becomes too slow, medications like atropine may be used. It is not known if dialysis can remove Plendil from the body.
Warnings
- Do not take Plendil if allergic to felodipine or ingredients in the tablet
- May cause very low blood pressure, leading to dizziness or fainting
- May increase heart rate and trigger chest pain in heart patients
- Use with caution in patients with heart failure or weak heart function
- Liver issues may require lower dose and regular BP monitoring
- Swelling in lower limbs common, especially in elderly or high doses
- May cause gum swelling – practice good dental hygiene
- Always swallow whole with water. Do not crush or chew
- Notify doctor of chest pain, swelling, dizziness, or other unusual symptoms
Contraindications
Plendil has no known absolute contraindications except for people who are allergic to felodipine or any of the ingredients in the tablet. If you have a history of severe allergic reactions to similar medications, your doctor may recommend a different treatment.
Interactions
Plendil may interact with many other treatments, including prescriptions, over-the-counter drugs, supplements, and herbal products.
Tell your doctor or pharmacist about everything you take. Known interacting drugs include:
- Itraconazole
- Ketoconazole
- Atazanavir
- Carbamazepine
- Ceritinib
- Clarithromycin
- Clopidogrel
- Conivaptan
- Cyclosporine
- Dantrolene
- Digoxin
- Doxorubicin
- Doxorubicin hydrochloride liposome
- Droperidol
- Duvelisib
- Epirubicin
- Fosnetupitant
- Idelalisib
- Ivosidenib
- Lacosamide
- Larotrectinib
- Lefamulin
- Lorlatinib
- Lumacaftor
- Mibefradil
- Morphine
- Morphine sulfate liposome
- Netupitant
- Nilotinib
- Pixantrone
- St John’s Wort
- Amprenavir
- Dalfopristin
- Fluconazole
- Indinavir
- Magnesium
- Nelfinavir
- Oxcarbazepine
- Phenobarbital
- Quinupristin
- Rifapentine
Storage Information
Keep Plendil in a cool, dry place below 30°C or 86°F. Store it in the original container with the lid closed tightly. Keep it away from sunlight, heat, and moisture. Do not store it in the bathroom. Make sure children and pets cannot reach it.
Cost & Coupons
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Frequently Asked Questions
Disclaimer
Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.
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