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What is Remicade?

Remicade (infliximab) is a prescription medicine used to treat several conditions, including rheumatoid arthritis in adults, Crohn’s disease in children 6 years and older and adults, ankylosing spondylitis in adults, psoriatic arthritis in adults, plaque psoriasis in adults, and ulcerative colitis in children 6 years and older and adults.

Remicade is available as a 100 mg dose in a vial of lyophilized powder that is reconstituted and diluted for injection.

Common side effects include respiratory infections, headaches, coughing, and stomach pain. Infusion reactions, like fever and chills, can also occur during or after receiving Remicade.

How Does Remicade Work?

Remicade targets a specific protein in the body called tumor necrosis factor-alpha (TNF-alpha).

This protein helps the immune system fight infections. However, in some diseases, the body produces too much TNF-alpha, causing the immune system to attack healthy tissues, leading to inflammation and damage.

Remicade blocks TNF-alpha’s action, reducing inflammation and preventing further tissue damage. This helps improve symptoms and manage the conditions for which Remicade is prescribed.

Dosage Information and Usage

Remicade is a medication used to treat various inflammatory conditions by reducing inflammation.

It is administered through an intravenous (IV) infusion, where the medicine is given directly into the bloodstream through a vein.

The dosage and frequency of Remicade depend on the specific condition being treated and the patient’s response to the therapy.

Dosage form and strengths of Remicade

Remicade comes in a 100 mg single-dose vial as a white powder. It needs to be mixed and diluted before use.

Administration of Remicade

Remicade is administered through an IV infusion, meaning it goes directly into a vein in your arm.

A healthcare professional will give you the medicine over about two hours. You might receive additional medication beforehand to prevent or reduce side effects. During and after the infusion, you’ll be monitored for side effects.

If you experience any, the infusion rate may be adjusted, or the treatment paused or stopped. Your doctor will determine the right dose and frequency, so attending all scheduled infusions and follow-up appointments is important to ensure the best results and monitor your progress.

Storage Information

Remicade is supplied in a carton containing a single-dose vial, each holding 100 mg of infliximab as a sterile, preservative-free, white lyophilized powder. It should be stored in a refrigerator at temperatures between 2°C and 8°C (36°F and 46°F).

If necessary, unopened vials can be stored at room temperature, up to 30°C (86°F), for up to six months, but not beyond the original expiration date. The new expiration date should be written on the carton. Once removed from the refrigerator, the vials should not be returned to it.

Side Effects of Remicade

Remicade can cause a range of side effects, from common and mild to serious and rare. It’s important to be aware of these potential reactions so you can recognize them and inform your doctor if they occur.

Your healthcare provider will monitor you closely for side effects during and after your treatment.

Common Side Effects

  • Respiratory infections (such as sinus infections and sore throat)
  • Headache
  • Coughing
  • Stomach pain
  • Fever
  • Chills
  • Chest pain
  • Low or high blood pressure
  • Shortness of breath
  • Rash
  • Itching

Serious but Rare Side Effects of Remicade

  • Serious infections, including tuberculosis (TB), and infections caused by viruses, fungi, or bacteria
  • Reactivation of hepatitis B virus in chronic carriers
  • Congestive heart failure or worsening of existing heart failure
  • Heart attack, low blood flow to the heart, or abnormal heart rhythm
  • Serious liver problems, such as jaundice or dark brown-colored urine
  • Blood problems, including low blood cell counts
  • Nervous system disorders, such as vision changes, numbness, or seizures
  • Stroke
  • Severe allergic reactions, including hives, difficulty breathing, and chest pain
  • Delayed allergic reactions, occurring 3 to 12 days after treatment
  • Lupus-like syndrome, with symptoms like chest pain, shortness of breath, and joint pain
  • New or worsening psoriasis

Always notify your doctor immediately if you experience any signs of infection, heart problems, liver issues, blood disorders, nervous system problems, allergic reactions, lupus-like symptoms, or psoriasis while receiving Remicade.

Warnings and Precautions

Remicade (infliximab) is a strong medication for treating various inflammatory conditions. However, it’s important to know the potential risks and take precautions to ensure safe and effective treatment.

Boxed Warnings for Remicade

Remicade can cause serious infections, which may even be fatal.

  • Increased Infection Risk: Higher chance of infections if using medications that weaken the immune system (e.g., methotrexate, corticosteroids).
  • Severe Infection Warning: Stop using Remicade if you develop a severe infection or sepsis.
  • Types of Infections: Includes tuberculosis (TB), severe fungal, and bacterial or viral infections from opportunistic germs.
  • TB Testing: Get tested and treated for TB before starting Remicade. Monitor for signs of infection during and after use, even if initially TB-negative.
  • Cancer Risk: Risk of certain cancers like lymphoma, especially in children and teens on Remicade or similar drugs.
  • Rare Cancer: Rare cancer was observed in users of TNF blockers like Remicade, especially when taken with azathioprine or 6-mercaptopurine.

It’s important to understand these risks and discuss the benefits and dangers of using Remicade with your doctor.

General Precautions for Remicade Medication

Before starting treatment with Remicade, several precautions should be considered to minimize potential risks and manage side effects effectively.

  • Infection Risk: Patients using Remicade have a higher chance of developing severe infections, which can be life-threatening. This is because Remicade suppresses the immune system, making it harder for the body to fight infections.
  • Tuberculosis Screening: Patients must be tested for latent tuberculosis (TB) before starting Remicade and periodically during treatment. If a patient has latent TB, treating it before starting Remicade can prevent the infection from becoming active.
  • Hepatitis B Screening: Patients should be tested for hepatitis B virus (HBV) before starting Remicade. If a patient is a carrier, they need close monitoring, as HBV can reactivate, potentially causing severe liver damage.
  • Heart Failure Monitoring: Patients with heart failure should use Remicade cautiously. Higher doses can worsen heart failure or increase the risk of hospitalization and death. Monitoring and adjusting treatment are necessary if symptoms worsen.
  • Cancer Risk: Remicade may increase the risk of developing certain cancers, such as lymphomas and skin cancers. Regular check-ups and skin examinations are recommended, especially for patients with risk factors for these cancers.
  • Liver Function: Severe liver reactions can occur with Remicade, sometimes leading to liver failure. Patients should be monitored for signs of liver dysfunction, and the medication should be discontinued if significant liver issues develop.
  • Blood Disorders: Some patients may develop serious blood disorders like leukopenia (low white blood cell count) or thrombocytopenia (low platelet count). Immediate medical attention is necessary if symptoms such as persistent fever or bleeding occur.
  • Hypersensitivity Reactions: Remicade can cause allergic reactions, which can be severe and require immediate treatment. Symptoms can include rash, difficulty breathing, and swelling.
  • Neurological Disorders: Remicade may be linked to new or worsening neurological conditions, including multiple sclerosis or seizures. Patients with these conditions should use Remicade cautiously and be monitored for new symptoms.
  • Simultaneous Use with Other Biologics: Using Remicade with other biological medications can increase the risk of infections. It’s generally advised not to combine these therapies.
  • Autoimmunity: Remicade can cause the body to produce autoantibodies, leading to conditions similar to lupus. If this occurs, discontinuing Remicade is recommended.
  • Vaccinations: Live vaccines should not be given to patients on Remicade, as they can cause infections. All vaccinations should be updated before starting treatment with Remicade.

Overdosage of Remicade

Taking too much Remicade at once, even up to 20 mg/kg, hasn’t shown any direct harmful effects. But if you think you’ve taken too much, it’s important to get help right away. Your doctor may watch you closely for any signs of side effects and provide treatment for them as needed. It’s necessary to act quickly and get the right care if you’ve taken too much Remicade.

Cost & Discounts

Remicade Canada Buying medications in America can be expensive, but with Pharma Giant (PG), you can find affordable options for Remicade. Their secure online platform allows you to conveniently purchase your prescription at much lower prices than traditional rates.

Pharma Giant (PG) offers a wallet-friendly solution for Remicade. With a valid prescription, you can easily order Remicade online through PG’s safe platform at significantly reduced prices.

Pricing Table

100mg1 vial$1499.00
100mg2 vials$2960.00
100mg3 vials$4380.00

These lower-cost options make managing your health more affordable without spending more.

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Assurance of Quality and Timely Delivery At Pharma Giant (PG), we are committed to delivering high-quality medication and efficient service.

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Pharma Giant (PG) provides a cost-effective and reliable solution for purchasing Remicade online, ensuring high quality and timely delivery, with additional discounts for new customers.

Drug Interactions of Remicade With Other Medications

It’s important to know how Remicade interacts with other drugs for your safety. Here’s a closer look at each interaction:

  • Combination with Other Biological Products: Mixing Remicade with other drugs meant to treat the same conditions isn’t recommended. Doing so might increase your risk of severe infections. Even though other TNF blockers may be effective, combining them with Remicade doesn’t provide any extra benefits and may lead to harmful side effects.
  • Methotrexate and Other Concurrent Medications: While Remicade studies haven’t specifically tested interactions with methotrexate, many patients used other medications alongside Remicade. These include pain relievers, corticosteroids, and antibiotics, which could influence how Remicade works. Taking methotrexate with Remicade might lower your chances of developing antibodies against Remicade, making it more effective.
  • Immunosuppressants: People with Crohn’s disease (CD) who took immunosuppressants had fewer reactions during Remicade infusions. Even if patients were on corticosteroids, antibiotics, or aminosalicylates, it didn’t affect Remicade levels in their blood. This suggests that combining Remicade with these immunosuppressants could help manage CD symptoms without reducing Remicade’s effectiveness.
  • Cytochrome P450 Substrates: Remicade might impact the production of certain enzymes in your body, which can affect how other drugs are metabolized. If you’re taking medications that rely on these enzymes for processing, such as warfarin or cyclosporine, your doctor may need to monitor your levels more closely and adjust your dosage as needed to ensure your safety and effectiveness of treatment.
  • Live Vaccines/Therapeutic Infectious Agents: It’s important to avoid receiving live vaccines while on Remicade treatment. Live vaccines may cause serious infections when your immune system is already suppressed by Remicade. Additionally, if you were exposed to Remicade in the womb, it’s best to wait at least 6 months after birth before getting live vaccines to reduce the risk of complications. Similarly, using therapeutic infectious agents alongside Remicade isn’t recommended, as it may increase the risk of infections and other adverse effects.

Alternative Medications to Remicade

When considering treatment options beyond Remicade, several alternatives are available:

Make sure to ask your healthcare provider about these alternative medications to Remicade to find the best option for your treatment needs.


Remicade infusions are a method of delivering Remicade. It’s given directly into a vein through a process called infusion. This treatment can help alleviate symptoms and even achieve remission, especially for conditions like Crohn’s disease when other treatments haven’t been effective.

Remicade is mainly made up of a special protein called infliximab, which is the active ingredient. This protein is a type of monoclonal antibody, made using a mix of human and mouse proteins using advanced technology. Monoclonal antibodies are like small proteins that can attach themselves to specific proteins in our bodies.

Remicade typically stays in your system for quite a while. Doctors often use something called a half-life to figure out how long a drug lasts in your blood. For Remicade, it takes about 7 to 9 days for your body to get rid of half of the dose you received. So, in total, Remicade can stay around in your body for about 28 to 45 days.

Yes, Remicade can potentially cause high blood pressure. While receiving a Remicade infusion or afterward, serious issues related to the brain, heart, and blood vessels may arise. These can include heart attack, stroke, high blood pressure, and low blood pressure.

No, Remicade does not work immediately. It may take several weeks to several months before you notice any improvement in your symptoms, depending on the condition being treated. It’s essential to discuss with your doctor to understand how long it might take for the medication to start working for you.

If Remicade is safe and effective for you, you may continue taking it for the long term. However, if you’re an adult with Crohn’s disease and Remicade doesn’t improve your condition after 14 weeks, your doctor may consider switching you to a different medication.

Remicade can make you feel tired for various reasons. Sometimes, it’s a side effect, especially if you’re experiencing infections or liver issues. Additionally, fatigue can be a symptom of autoimmune diseases, where your immune system mistakenly attacks your body. Inflammation, which causes swelling, can also contribute to feeling tired.

Administering Remicade by specially trained general practitioners under the guidance of rheumatologists or gastroenterologists appears to be a safe and acceptable approach for long-term treatment with Remicade in patients who require biological treatment.

Remicade and Humira are both effective medications for treating various conditions like inflammatory bowel disease and rheumatoid arthritis. However, their safety profiles may vary from person to person. While both drugs can have side effects, such as increased risk of infections or infusion reactions, the choice between Remicade and Humira depends on individual factors, including medical history, treatment response, and potential side effects.

Remicade may not be suitable for everyone, particularly individuals with specific medical conditions. For instance, individuals with heart failure, hepatitis B virus (HBV) infection, or nervous system disorders like multiple sclerosis or Guillain-Barré syndrome should avoid taking Remicade.

For adults with moderately to severely active Crohn’s disease, Remicade is typically administered intravenously (IV) in an initial phase at weeks 0, 2, and 6, followed by maintenance doses every 8 weeks thereafter. The recommended dose is 5 mg/kg.

No, Remicade isn’t a chemotherapy drug. Unlike chemotherapy, which targets cancer cells, Remicade works on the immune system to reduce its activity. It targets specific proteins involved in immune function.

Yes, Remicade is considered a high-risk medication. Patients treated with Remicade (infliximab) are at an increased risk of developing serious infections that may lead to hospitalization or death. Given its risks, it’s important to consult with your healthcare provider before starting Remicade treatment. They can assess your health status and discuss whether the potential benefits outweigh the risks for your specific situation.