What is Repatha?
Repatha (Evolocumab) is an injectable prescription medicine used for the following:
- In adults with cardiovascular disease: To reduce the risk of heart attack, stroke, and certain types of heart surgery.
- For adults with high blood cholesterol levels: Along with diet alone or together with other cholesterol-lowering medicines in adults with primary hyperlipidemia (including a type of high cholesterol called heterozygous familial hypercholesterolemia [HeFH]) to reduce low-density lipoprotein (LDL) or bad cholesterol.
- In children aged 10 years and older with HeFH: Along with diet and other LDL-lowering medicines to reduce LDL cholesterol.
- For adults and children aged 10 years and older with homozygous familial hypercholesterolemia (HoFH): Along with other LDL-lowering medicines to reduce LDL cholesterol.
It is not known if Repatha is safe and effective in children with HeFH or HoFH who are younger than 10 years of age or in children with other types of hyperlipidemia.
How Does Repatha Work?
Repatha works by targeting a protein called PCSK9 in the body. When PCSK9 is blocked, it allows more LDL receptors (LDLRs) to be available on the surface of liver cells.
These receptors help to clear LDL cholesterol from the bloodstream, leading to lower levels of LDL-C (low-density lipoprotein cholesterol).
So, Repatha essentially helps to reduce LDL-C concentrations by increasing the liver’s ability to remove LDL cholesterol from the blood.
Dosage Information and Usage
Repatha is a medication used to treat certain heart and cholesterol conditions. It’s important to use it correctly to get the best results and avoid missing doses.
Dosage Form and Strengths of Repatha
Repatha comes in different forms and strengths:
- Injection: 140 mg/mL solution in a single-dose prefilled syringe
- Injection: 140 mg/mL solution in a single-dose prefilled SureClick® autoinjector
- Injection: 420 mg/3.5 mL solution in a single-dose Pushtronex® system (on-body infusor with prefilled cartridge)
Administration
To use Repatha, follow your doctor’s instructions carefully. It’s given as an injection under the skin, either every 2 weeks or once a month, depending on what your doctor recommends for your condition.
If you have a certain type of high cholesterol, you might start with a higher dose once a month, and your doctor might adjust it later.
There are different ways to give the injection, like using a special device or doing it manually. Your doctor will show you or your caregiver how to do it correctly.
Always inject it into the thigh, upper arm, or stomach, avoiding areas that are sore or bruised. If you miss a dose, try to take it within 7 days. If it’s been longer, ask your doctor what to do next.
Storage Information
To store Repatha safely, keep it in its original carton in the refrigerator between 36°F and 46°F (2°C to 8°C). Don’t freeze or shake the medication.
You can also store Repatha at room temperature between 68°F and 77°F (20°C to 25°C) in the original carton for up to 30 days. If not used within 30 days, dispose of it.
Note that the needle cover of the glass single-dose prefilled syringe and the single-dose prefilled autoinjector contain latex, while the single-dose on-body infusor with prefilled cartridge does not.
Side Effects of Repatha
Repatha, like any medication, may cause side effects. It’s essential to be aware of these potential reactions and discuss them with your healthcare provider.
Common Side Effects:
- Runny nose
- Sore throat
- Symptoms of the common cold
- Flu or flu-like symptoms
- Back pain
- High blood sugar levels (diabetes)
- Redness, pain, or bruising at the injection site
Serious but Rare Side Effects
- Trouble breathing or swallowing
- Raised bumps (hives)
- Rash or itching
- Swelling of the face, lips, tongue, throat, or arms
Warnings and Precautions
Before starting Repatha, it’s important to know the potential risks and precautions. Always share your full medical history with your healthcare provider to make sure Repatha is suitable for you.
General Precautions for Repatha Medication
Before starting Repatha, it’s important to be aware of some general precautions to ensure the safe use of the medication.
- Hypersensitivity Reactions: Some patients may experience hypersensitivity reactions, like angioedema while taking Repatha. If you notice signs of a serious allergic reaction—such as difficulty breathing or swallowing, hives, rash, or swelling of the face, lips, tongue, throat, or arms—stop using Repatha and seek medical help immediately. Do not use Repatha if you have a history of severe allergic reactions to evolocumab or any of its components.
- Latex Allergy: The needle cover of the glass single-dose prefilled syringe and the single-dose prefilled autoinjector contain dry natural rubber (a derivative of latex). Individuals who are sensitive to latex may experience an allergic reaction. If you have a latex allergy, discuss it with your healthcare provider before using Repatha to determine the best course of action.
Alternative Medications
While Repatha is an effective treatment for lowering bad cholesterol levels, it may not be suitable for everyone due to various reasons, such as potential side effects.
Here are some of the alternative medications to Repatha:
- Questran (cholestyramine)
- Lopid (gemfibrozil)
- Trilipix (fenofibric acid)
- Fenoglide (fenofibrate)
- Vascepa (icosapent ethyl)
- Vytorin (ezetimibe/simvastatin)
- Mevacor (lovastatin)
- Livalo (pitavastatin)
Cost & Discounts: Repatha Canada
Purchasing medications in the United States can be expensive, but you can save money by buying Repatha from Pharma Giant. At Pharma Giant, we believe everyone should have access to quality medication without financial strain.
Discover Our Repatha (Evolocumab) Options:
| Strength | Quantity | Price |
|---|---|---|
| 140mg | 2 injections | $749.00 |
| 4 injections | $1480.00 | |
| 6 injections | $2100.00 | |
| 420mg/3.5mL | 1 dose | $849.00 |
| 2 doses | $1640.00 | |
| 3 doses | $2400.00 |
We understand the importance of managing your health without worrying about high costs. With Pharma Giant, you can trust in affordable prices and quality medication.
Special Discount Offer
Pharma Giant is pleased to offer a special discount to help you save on your Repatha purchase. Use the promo code PGSAVE10 at checkout to receive a 10% discount. This exclusive offer is here to make your medication more affordable.
Note: This code can only be used once per customer and is valid for a limited time.
Take advantage of this fantastic deal and make your purchase more economical with Pharma Giant today.
Savings on Bulk Purchases
Buying in bulk can further reduce your costs. Pharma Giant offers competitive pricing for larger quantities, ensuring you get the best value for your money.
Assurance of Quality and Timely Delivery
At Pharma Giant, we ensure top-quality medication and quick delivery to your door. With our express shipping, you can expect delivery within 3-5 business days across the US. We ship orders in secure containers to protect your medication during transit.
Our goal is to ensure essential treatments are accessible and affordable for all, even without insurance.
Frequently Asked Questions
Disclaimer
Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.
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