Have a prescription? Purchase Repatha from Canada and experience several benefits, including:

  • Significant Cost Savings: Order Repatha at lower prices compared to the US.
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Starting from $749

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Prescription Required.Product of Canada.Shipped from Canada.

What is Repatha?

Repatha (Evolocumab) is an injectable prescription medicine used for the following:

  • In adults with cardiovascular disease: To reduce the risk of heart attack, stroke, and certain types of heart surgery.
  • For adults with high blood cholesterol levels: Along with diet alone or together with other cholesterol-lowering medicines in adults with primary hyperlipidemia (including a type of high cholesterol called heterozygous familial hypercholesterolemia [HeFH]) to reduce low-density lipoprotein (LDL) or bad cholesterol.
  • In children aged 10 years and older with HeFH: Along with diet and other LDL-lowering medicines to reduce LDL cholesterol.
  • For adults and children aged 10 years and older with homozygous familial hypercholesterolemia (HoFH): Along with other LDL-lowering medicines to reduce LDL cholesterol.

It is not known if Repatha is safe and effective in children with HeFH or HoFH who are younger than 10 years of age or in children with other types of hyperlipidemia.

How Does Repatha Work?

Repatha works by targeting a protein called PCSK9 in the body. When PCSK9 is blocked, it allows more LDL receptors (LDLRs) to be available on the surface of liver cells.

These receptors help to clear LDL cholesterol from the bloodstream, leading to lower levels of LDL-C (low-density lipoprotein cholesterol).

So, Repatha essentially helps to reduce LDL-C concentrations by increasing the liver’s ability to remove LDL cholesterol from the blood.

Dosage Information and Usage

Repatha is a medication used to treat certain heart and cholesterol conditions. It’s important to use it correctly to get the best results and avoid missing doses.

Dosage Form and Strengths of Repatha

Repatha comes in different forms and strengths:

  • Injection: 140 mg/mL solution in a single-dose prefilled syringe
  • Injection: 140 mg/mL solution in a single-dose prefilled SureClick® autoinjector
  • Injection: 420 mg/3.5 mL solution in a single-dose Pushtronex® system (on-body infusor with prefilled cartridge)


To use Repatha, follow your doctor’s instructions carefully. It’s given as an injection under the skin, either every 2 weeks or once a month, depending on what your doctor recommends for your condition.

If you have a certain type of high cholesterol, you might start with a higher dose once a month, and your doctor might adjust it later.

There are different ways to give the injection, like using a special device or doing it manually. Your doctor will show you or your caregiver how to do it correctly.

Always inject it into the thigh, upper arm, or stomach, avoiding areas that are sore or bruised. If you miss a dose, try to take it within 7 days. If it’s been longer, ask your doctor what to do next.

Storage Information

To store Repatha safely, keep it in its original carton in the refrigerator between 36°F and 46°F (2°C to 8°C). Don’t freeze or shake the medication.

You can also store Repatha at room temperature between 68°F and 77°F (20°C to 25°C) in the original carton for up to 30 days. If not used within 30 days, dispose of it.

Note that the needle cover of the glass single-dose prefilled syringe and the single-dose prefilled autoinjector contain latex, while the single-dose on-body infusor with prefilled cartridge does not.

Side Effects of Repatha

Repatha, like any medication, may cause side effects. It’s essential to be aware of these potential reactions and discuss them with your healthcare provider.

Common Side Effects:

  • Runny nose
  • Sore throat
  • Symptoms of the common cold
  • Flu or flu-like symptoms
  • Back pain
  • High blood sugar levels (diabetes)
  • Redness, pain, or bruising at the injection site

Serious but Rare Side Effects

  • Trouble breathing or swallowing
  • Raised bumps (hives)
  • Rash or itching
  • Swelling of the face, lips, tongue, throat, or arms

Warnings and Precautions

Before starting Repatha, it’s important to know the potential risks and precautions. Always share your full medical history with your healthcare provider to make sure Repatha is suitable for you.

General Precautions for Repatha Medication

Before starting Repatha, it’s important to be aware of some general precautions to ensure the safe use of the medication.

  • Hypersensitivity Reactions: Some patients may experience hypersensitivity reactions, like angioedema while taking Repatha. If you notice signs of a serious allergic reaction—such as difficulty breathing or swallowing, hives, rash, or swelling of the face, lips, tongue, throat, or arms—stop using Repatha and seek medical help immediately. Do not use Repatha if you have a history of severe allergic reactions to evolocumab or any of its components.
  • Latex Allergy: The needle cover of the glass single-dose prefilled syringe and the single-dose prefilled autoinjector contain dry natural rubber (a derivative of latex). Individuals who are sensitive to latex may experience an allergic reaction. If you have a latex allergy, discuss it with your healthcare provider before using Repatha to determine the best course of action.

Alternative Medications

While Repatha is an effective treatment for lowering bad cholesterol levels, it may not be suitable for everyone due to various reasons, such as potential side effects.

Here are some of the  alternative medications to Repatha:

  • Questran (cholestyramine)
  • Lopid (gemfibrozil)
  • Trilipix (fenofibric acid)
  • Fenoglide (fenofibrate)
  • Vascepa (icosapent ethyl)
  • Vytorin (ezetimibe/simvastatin)
  • Mevacor (lovastatin)
  • Livalo (pitavastatin)

Cost & Discounts: Repatha Canada

Purchasing medications in the United States can be expensive, but you can save money by buying Repatha from Pharma Giant. At Pharma Giant, we believe everyone should have access to quality medication without financial strain.

Discover Our Repatha (Evolocumab) Options:

140mg2 injections$749.00
4 injections$1480.00
6 injections$2100.00
420mg/3.5mL1 dose$849.00
2 doses$1640.00
3 doses$2400.00

We understand the importance of managing your health without worrying about high costs. With Pharma Giant, you can trust in affordable prices and quality medication.

Special Discount Offer

Pharma Giant is pleased to offer a special discount to help you save on your Repatha purchase. Use the promo code FIRST10 at checkout to receive a 10% discount. This exclusive offer is here to make your medication more affordable.

Note: This code can only be used once per customer and is valid for a limited time.

Take advantage of this fantastic deal and make your purchase more economical with Pharma Giant today.

Savings on Bulk Purchases

Buying in bulk can further reduce your costs. Pharma Giant offers competitive pricing for larger quantities, ensuring you get the best value for your money.

Assurance of Quality and Timely Delivery

At Pharma Giant, we ensure top-quality medication and quick delivery to your door. With our express shipping, you can expect delivery within 3-5 business days across the US. We ship orders in secure containers to protect your medication during transit.

Our goal is to ensure essential treatments are accessible and affordable for all, even without insurance.


Repatha is usually given either every 2 weeks with a dosage of 140 mg or once a month with a dosage of 420 mg. These doses are administered under the skin (subcutaneously).

Yes, Repatha can cause joint pain, but this side effect is not very common. It was reported in studies, that joint pain can sometimes be related to other side effects like fatigue and flu-like symptoms.

No, Repatha isn’t known to cause weight loss. Weight loss wasn’t reported as a side effect in studies of the drug.

Repatha effectively lowers LDL cholesterol levels. In the Fourier clinical trial, Repatha reduced LDL cholesterol by 57% within four weeks, bringing levels down to 54 mg/dL. With regular dosing, this reduction stayed at least 50% below the original baseline levels for 168 weeks.

People who qualify for Repatha generally have high cholesterol conditions that can’t be managed with diet and exercise alone. This includes those with familial hypercholesterolemia (a genetic condition causing very high cholesterol), atherosclerotic cardiovascular disease (heart attacks or strokes), and patients needing extra lipid-lowering therapies because their LDL cholesterol remains high despite maximum statin doses.

Repatha lowers LDL cholesterol quickly, with significant reductions seen in just one month. When combined with a statin, patients achieved an average reduction of 63% in bad cholesterol levels within three months.

You can tell Repatha is working if your LDL cholesterol levels drop within the first month of taking it. Also, within the first year, you should see a noticeable reduction in the risk of heart attack, stroke, and coronary revascularization. Regular blood tests can confirm these changes.

Yes, you can take Repatha at night. However, many people prefer to inject it during the day because it takes 30 to 45 minutes to warm up to room temperature, and it’s easier to see what you’re doing in daylight.

If you stop taking Repatha, your LDL cholesterol levels will start to increase again once the medication has left your body. Repatha needs to be taken long-term to maintain its beneficial effects. Follow your doctor’s instructions carefully and do not stop taking the medication without consulting them first.

Repatha stays in your body for a while. Its half-life is between 11 and 17 days, which means it takes that long for half of the medication to be cleared from your body. After another 11 to 17 days, only 25% of the medication will be left.