Revatio (sildenafil citrate)
from$1499
$6295
Revatio Sildenafil Citrate
Select product strength & quantity:
Prescription Required
Ships within 4-10 Business Days
Express Ships from Canada
Product of Canada
from$899
$6295
Revatio Sildenafil Citrate
Select product strength & quantity:
Prescription Required
Ships within 15-20 Business Days
Express Ships from UK
Product of UK

What is Revatio (Sildenafil Citrate)?

Revatio (sildenafil) is used to treat pulmonary arterial hypertension (PAH). Under the brand name Viagra and its generic, it is also used for erectile dysfunction.

It works by relaxing the muscles in blood vessels, which helps increase blood flow. For PAH, Revatio lowers blood pressure in the lungs, improves exercise ability, and slows the disease’s progression.

For erectile dysfunction, it increases blood flow to the penis, helping achieve and maintain an erection.

Revatio comes in three forms:

  • tablets (20mg),
  • injectable solution (10mg/12.5mL),
  • and oral suspension (10mg/mL)

Depending on the formulation, it can be administered orally or injected into a vein. It is prescribed for both adults and children aged 1-17 for PAH, while Viagra, another form of sildenafil, is used for erectile dysfunction in adults.

Common side effects include headaches, indigestion, and flushing. Serious side effects, such as chest pain or vision problems, need immediate medical attention.

Patients should inform their doctor about all medications they are taking to avoid interactions. If a dose is missed, take it as soon as possible, but skip it if the next dose is near. In case of an overdose, seek emergency medical help.

Store Revatio oral suspension in the refrigerator and discard it after 60 days. Keep all forms of Revatio out of children’s reach.

Uses of Revatio

  • Pulmonary Arterial Hypertension (PAH): A type of high blood pressure that affects the arteries in the lungs and the right side of the heart. Revatio helps reduce this pressure, improving exercise capacity and overall heart function.
  • Erectile Dysfunction: Difficulty in achieving or maintaining an erection sufficient for sexual activity. Revatio helps by increasing blood flow to the penis, aiding in getting and keeping an erection.

How Does Revatio Work?

Revatio works by relaxing the muscles in the walls of blood vessels, which increases blood flow to certain areas of the body.

It does this by blocking a specific enzyme called phosphodiesterase-5 (PDE-5).

For pulmonary arterial hypertension (PAH), Revatio helps widen the blood vessels in the lungs, lowering the pressure in the arteries and making it easier to exercise.

For erectile dysfunction, it boosts blood flow to the penis, helping to achieve and maintain an erection.

By inhibiting PDE-5, Revatio allows a substance called cGMP to build up, which helps relax and open the blood vessels.

Dosage Information and Usage

Dosage Form and Strengths of Revatio

  • Revatio Tablets: 20 mg
  • Revatio Injectable Solution: 10 mg/12.5 mL
  • Revatio Powder for Oral Suspension: 10 mg/mL (when reconstituted)

Recommended Dosage for Revatio For Adults

Pulmonary Arterial Hypertension (PAH):

  • Oral Tablets: 20 mg, taken three times a day (TID). Your doctor may increase the dose up to 80 mg TID based on symptoms and tolerance.
  • Injectable Solution: 10 mg administered as an intravenous bolus three times a day.

Erectile Dysfunction (Viagra, not Revatio):

  • Oral Tablets: 50 mg, taken about 1 hour before sexual activity. The dose can be adjusted between 25 mg and 100 mg based on effectiveness and side effects.

Dosage Adjustments (in adults)

  • Liver Problems (Hepatic Impairment): For severe liver issues, the starting dose might be lower, and adjustments depend on individual tolerance. No changes needed for mild or moderate liver problems.
  • Kidney Problems (Renal Impairment): For severe kidney issues (CrCl <30 mL/min), starting with a lower dose is advised. No dose adjustment is needed for mild to moderate kidney problems.

Recommended Dosage for Revatio For Children

Pulmonary Arterial Hypertension (PAH):

  • Children weighing less than 20 kg: 10 mg, taken three times a day.
  • Children weighing 20 kg to 45 kg: 20 mg, taken three times a day.
  • Children weighing 45 kg or more: 20 mg, taken three times a day, with a possible increase to 40 mg three times a day based on symptoms and tolerance.

Dosage Adjustments (in children)

  • Liver Problems (Hepatic Impairment): No dose change needed for mild or moderate liver problems. For severe liver issues, the effect of Revatio is unclear as it has not been extensively studied.
  • Kidney Problems (Renal Impairment): No dose adjustments are necessary regardless of the severity of kidney problems.

Recommended Dosage for Revatio For the Elderly

Pulmonary Arterial Hypertension (PAH):

  • Oral Tablets: 20 mg, taken three times a day. The dose can be increased up to 80 mg three times a day, depending on symptoms and tolerance.
  • Injectable Solution: 10 mg administered intravenously three times a day.

Erectile Dysfunction (Viagra only):

  • Oral Tablets: Start with 25 mg, taken about 1 hour before sexual activity. The dose can be adjusted between 25 mg and 100 mg based on individual response.

Dosage Adjustments (in the elderly)

  • Liver and Kidney Problems: Elderly patients with liver or kidney issues should follow similar dosage adjustments as those recommended for younger adults, starting with lower doses and adjusting based on tolerance and effectiveness.

Usage

Revatio should be taken exactly as prescribed by your doctor.

For oral tablets, the typical dosage is three times a day, with each dose spaced about 4 to 6 hours apart.

The injectable solution is administered as an intravenous bolus three times a day. If you are using the oral suspension, make sure to shake it well before use.

Always follow the instructions on your prescription label and read any medication guides provided to ensure proper usage.

Contraindications of Revatio

Revatio should not be used by individuals who are taking organic nitrates, whether regularly or occasionally, because it can cause dangerously low blood pressure.

It is also not recommended for people using riociguat, a medication that can increase the risk of severe drops in blood pressure when combined with Revatio.

If you are allergic to sildenafil or any ingredient in Revatio, you should avoid using this medication. Allergic reactions to sildenafil, including severe reactions like anaphylaxis, have been reported.

Storage Information

Revatio should be stored carefully to maintain its effectiveness.

The tablets should be kept at room temperature, between 20°C and 25°C (68°F and 77°F), but can tolerate temperatures ranging from 15°C to 30°C (59°F to 86°F) if necessary.

The injection solution must also be stored at room temperature, within the same range of 20°C to 25°C (68°F to 77°F), and can handle temperatures from 15°C to 30°C (59°F to 86°F).

The powder for oral suspension should be stored in its original package, in a cool, dry place below 30°C (86°F).

After reconstitution, the oral suspension should be kept either below 30°C (86°F) or in the refrigerator at 2°C to 8°C (36°F to 46°F) and should not be frozen.

Any remaining oral suspension should be discarded 60 days after reconstitution.

Side Effects of Revatio

Common Side Effects

  • Nosebleeds
  • Headache
  • Upset stomach
  • Flushing (redness or warmth in the face)
  • Arm or leg pain
  • Muscle aches and pain
  • Back pain
  • Diarrhea

Serious but Rare Side Effects

  • Decreased blood pressure
  • Sudden decrease or loss of vision in one or both eyes (possible non-arteritic anterior ischemic optic neuropathy)
  • Sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness
  • An erection lasting more than 4 hours (priapism), which requires immediate medical attention

Warnings and Precautions

  • Hypotension: Revatio can lower blood pressure temporarily, which might be risky for patients with conditions like low blood pressure, severe fluid loss, or heart issues. Monitor blood pressure closely if using blood pressure-lowering medications.
  • Worsening Pulmonary Vascular Occlusive Disease: Revatio may worsen conditions related to pulmonary veno-occlusive disease (PVOD), a type of blood vessel blockage in the lungs. Use is not recommended for patients with this condition.
  • Epistaxis: Revatio has been linked to nosebleeds in some patients, especially those with connective tissue disease (CTD) or those taking oral vitamin K antagonists. It’s not known how Revatio affects people with bleeding disorders or active peptic ulcers.
  • Visual Loss: Some users have reported sudden vision loss related to non-arteritic anterior ischemic optic neuropathy (NAION). This condition can lead to permanent vision loss and is more common in those with certain eye and blood vessel issues. Seek immediate medical attention if vision decreases suddenly.
  • Hearing Loss: There have been reports of sudden hearing loss, sometimes with ringing in the ears and dizziness, linked to PDE-5 inhibitors like Revatio. The exact cause is unclear, but seek prompt medical help if you experience sudden hearing changes.
  • Combination with Other PDE-5 Inhibitors: The safety of using Revatio with other PDE-5 inhibitors, like Viagra, is unknown. Do not combine Revatio with these medications.
  • Priapism: Use Revatio cautiously in men with certain penile conditions or those at risk of priapism (painful, prolonged erections). Seek immediate medical help if an erection lasts more than 4 hours to avoid long-term damage.
  • Vaso-occlusive Crisis in Sickle Cell Disease: In a limited study, Revatio was linked to more vaso-occlusive crises (painful episodes) in patients with pulmonary hypertension due to sickle cell disease. Its safety and effectiveness for these patients are not confirmed.

Overdosage of Revatio

If someone takes too much Revatio, they may experience more frequent or severe side effects compared to lower doses.

In studies, doses up to 800 mg showed similar types of adverse events as lower doses but with increased frequency and severity.

In the event of an overdose, general supportive care should be provided, such as monitoring and treating symptoms as needed.

Renal dialysis will not help to remove Revatio from the body more quickly because the drug is strongly bound to plasma proteins and is not eliminated through urine.

Cost & Discounts

At Pharma Giant, we prioritize your health. Getting the right medication shouldn’t break the bank. Our goal is to offer top-notch medications like Revatio at competitive prices, making healthcare more accessible.

Check out our Revatio options:

Revatio (Sildenafil Citrate) Canada Prices:

  • 20mg – 90 tabs – $1499
  • 20mg – 180 tabs – $2960
  • 20mg – 270 tabs – $4410

Revatio (Sildenafil Citrate) UK Prices:

  • 20mg – 90 tabs – $1499
  • 20mg – 180 tabs – $1780
  • 20mg – 270 tabs – $2640

Special Discount Offer

  • Coupon Code: Use PGSAVE10 at checkout to get a 10% discount on your Revatio purchase. This special, time-limited offer helps you save on important medications while keeping quality high.
  • Offer Details: The discount can be used once per customer, so make sure to take advantage of it while you can.

How to Order

  • Prescription Needed: Revatio can only be bought with a valid prescription to ensure safety and compliance with health rules.
  • Bulk Orders: Patients may order a maximum of a 90-day supply, making it easier for ongoing treatment and managing costs.

Quality Assurance and Timely Delivery

At Pharma Giant, we promise to deliver high-quality medication quickly to your home.

  • Fast Shipping: Medications are shipped expressly from Canada to anywhere in the US within 3-5 business days, so you get your order quickly.
  • Safe Packaging: Every order is sent in secure, tamper-proof packages, making sure your medication stays safe and in good shape during delivery.

Why Choose Pharma Giant?

With Pharma Giant, you can take care of your health without stressing about high prices. Enjoy great value and excellent service today!

Drug Interactions With Other Medications

  • Nitrates: Taking Revatio with nitrates in any form is not allowed because it can cause dangerous drops in blood pressure.
  • Strong CYP3A Inhibitors: Using Revatio with strong CYP3A inhibitors (medications that significantly affect how Revatio is broken down in the body) is not recommended, as it may increase the risk of side effects.
  • Moderate-to-Strong CYP3A Inducers: When Revatio is used with moderate-to-strong CYP3A inducers (medications that lower the levels of Revatio in the body), it may require dose adjustments. Increase the Revatio dose when starting such inducers, and reduce the dose when stopping them.

Alternative Medications

  • Letairis (ambrisentan)
  • Adcirca (tadalafil)
  • Opsumit (macitentan)
  • Tracleer (bosentan)
  • Safebo (bosentan)
  • Remodulin (treprostinil)

Frequently Asked Questions

Revatio is a medication prescribed to treat pulmonary arterial hypertension and improve the blood flow between the patient’s heart and lungs.

Revatio works by relaxing and widening blood vessels in the lungs and penis. In pulmonary arterial hypertension, it improves blood flow in the lungs, reducing symptoms and enhancing exercise ability. For erectile dysfunction, it increases blood flow to the penis, helping to achieve and maintain an erection.

The recommended dosage of Revatio varies depending on the condition being treated. For pulmonary arterial hypertension, it’s typically 20 mg taken three times a day. For erectile dysfunction, the usual dose is 50 mg taken as needed, about one hour before sexual activity.

Yes, Revatio can be taken with or without food. Food does not affect the way the medication works.

Yes, follow your doctor’s instructions for taking Revatio. If you are using the oral suspension, shake the bottle well before each use. For all forms, take Revatio at the same times each day to maintain even levels in your body.

Store Revatio tablets and injection at room temperature between 68°F and 77°F (20°C to 25°C). Keep the tablets in their original bottle, and the injection in its single-use vial. For the oral suspension, keep it below 86°F (30°C) in the original package to protect it from moisture. After reconstitution, store the oral suspension below 86°F (30°C) or in the refrigerator at 36°F to 46°F (2°C to 8°C) and use it within 60 days.

If you miss a dose of Revatio, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

Revatio can interact with other medications, which may affect how it works or increase the risk of side effects. Always inform your healthcare provider about all the medications and supplements you are taking before starting Revatio. This includes prescription drugs, over-the-counter medications, and herbal supplements.

In case of an overdose of Revatio, seek medical attention immediately. Overdose symptoms may include severe drops in blood pressure, vision changes, or prolonged erections. Standard supportive measures should be taken, as renal dialysis is not expected to help clear the medication due to its high protein binding.

Revatio is not recommended for use during pregnancy unless necessary, as its safety for unborn babies is not well-established. Women of childbearing age should use effective contraceptive methods while taking Revatio. If you are pregnant or breastfeeding, consult your healthcare provider before using Revatio.

Common side effects of Revatio include nosebleeds, headache, and an upset stomach. Users may also experience flushing, which is a reddening or warming of the face, as well as pain in the arms or legs. Muscle aches, back pain, and diarrhea are also possible.

Revatio usually begins to work within 30 minutes after taking it. For erectile dysfunction, it can be effective for up to 4 hours, though its effects may lessen after 2 hours. Make sure to use the specific brand prescribed by your doctor, as different brands may have different effects.

Alternatives to Revatio for treating pulmonary arterial hypertension include:
  • Letairis (ambrisentan)
  • Adcirca (tadalafil)
  • Opsumit (macitentan)
  • Tracleer (bosentan)
  • Remodulin (treprostinil)

A very serious allergic reaction to Revatio is rare. However, if you experience symptoms such as rash, itching, swelling, severe dizziness, or trouble breathing, seek medical help immediately.

Dispose of Revatio properly by following local disposal regulations. Do not flush medications down the toilet or pour them into drains unless instructed.

Revatio and Viagra both contain the same active ingredient, sildenafil. However, they are used to treat different conditions. Viagra is FDA-approved for erectile dysfunction, while Revatio is approved for pulmonary arterial hypertension (PAH). The strengths and dosages for these medications differ based on their intended use.

While taking Revatio, you should regularly see your doctor as advised. Typically, you will need follow-up visits to monitor your condition and any potential side effects.

While using Revatio, you should avoid:
  • Nitrates: Combining Revatio with nitrates can cause a dangerous drop in blood pressure.
  • Alcohol: Limit alcohol intake as it can increase the risk of side effects and may affect how well Revatio works.
  • Grapefruit Juice: This can interact with Revatio and affect its effectiveness.

Revatio can rarely affect vision or hearing. Some people may experience sudden vision changes or loss, including permanent blindness in one or both eyes, which is a serious condition called non-arteritic anterior ischemic optic neuropathy (NAION).

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

Have a prescription?

Order Revatio online today and enjoy a host of benefits, including:

 Customer Reviews
  • Cost Savings: Buy Revatio at LOWER PRICES compared to the US
  • Bulk Order Discounts: Enjoy additional savings with bulk orders of Revatio (up to 90-day supply)
  • Reliable Express Shipping: Fast and discreet delivery shipped directly to your doorstep
  • Exceptional Customer Service: Have a question? We’re delighted to help via live chat, email, or phone
  • Easy & Secure Ordering: Seamless online or phone ordering at 1-888-513-2294
  • SAVE 10% on first order with coupon code: PGSAVE10

Price Match Guarantee

Price Match Guarantee

We are committed to providing fair, competitive pricing on all medications. If you find a lower price on the same product at another verified Canadian online pharmacy, we’ll match it.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online pharmacy with a verifiable address.
  • The competitor’s price must be current and active (not from a past or future promotion).
  • The product must be identical in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be submitted before placing an order — adjustments cannot be made after purchase.
  • Price matching does not apply to used or expired products.
  • Requests can be submitted via live chat or phone prior to completing your order.

Note: Price matching does not currently apply to Mounjaro® , Ozempic® or Saxenda®. However, this policy may be updated in the future.
Kenneth Fill, PharmD, MBA Fill

Kenneth Fill, PharmD, MBA, is a clinical pharmacist specialist and medical writer with a strong background in ambulatory care, pharmacogenomics, and medical content development. Based in the state of Michigan, he provides expert guidance on chronic disease state management. Kenneth completed his PharmD and MBA at the University of Toledo and pursued post-graduate residency training in ambulatory care and community-based pharmacy. His diverse background also includes academic detailing, clinical education, and interdisciplinary collaboration to enhance patient outcomes.