Rybelsus (semaglutide)
Rybelsus
Semaglutide
Select product strength & quantity:
Select product strength & quantity:
Select product strength & quantity:

Prescription Required.

Product of Canada.

Shipped from Canada.

Prescription Required.Product of Canada.Shipped from Canada.

What is Rybelsus (semaglutide)?

Rybelsus is a prescription medication used to treat and improve blood sugar control in people with type 2 diabetes.

Rybelsus belongs to the drug class, glucagon-like peptide-1 (GLP-1) receptor agonists. It is the first and only GLP-1 receptor agonist that can be taken by mouth, making it a convenient alternative to the traditional injectable form of this medication.

What are the Indications for Rybelsus?

Rybelsus is indicated for the treatment of type 2 diabetes mellitus in adults. It is used to improve glycemic control in people who have not achieved adequate blood sugar control with diet and exercise alone or with other oral antidiabetic medications.

The drug can be used as monotherapy, meaning it can be taken alone, or in combination with other medications such as metformin, sulfonylureas, and insulin. It is important to note that Rybelsus is not recommended for the treatment of type 1 diabetes or diabetic ketoacidosis.

How is Rybelsus used?

Storage

Rybelsus should be stored at room temperature, between 68°F and 77°F (20°C and 25°C), in its original container.

Keep Rybelsus out of reach of children and pets.

Instruction

Take Rybelsus once daily, preferably in the morning, with or without food. The tablet should be swallowed whole with a glass of water and should not be chewed, crushed, or split.

Dosage

Rybelsus is available in tablet form in the following strengths: 3mg, 7mg, 14mg.

The starting dose of Rybelsus is 3 mg once daily, and the dose can be increased to 7 mg once daily after 30 days if needed. Your doctor may increase your dose to 14 mg once daily after an additional 30 days if your blood sugar is still not adequately controlled.

Side Effects

It’s important to understand that although Rybelsus is FDA-approved, it comes with side effects that may or may not affect you.

Before starting Rybelsus, you should discuss possible side effects with your doctor or pharmacist.

Common Side Effects

Not all side effects require medical attention. As your body adjusts to Rybelsus, side effects may go away.

Tell your doctor if you experience the following symptoms, and they become severe or do not go away on their own:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Decreased appetite
  • Indigestion
  • Headache

Serious Side Effects

Severe adverse reactions while using Rybelsus can occur. Seek emergency medical care or call 911 if you experience any of the following symptoms:

  • Severe allergic reaction: severe rash or itching, swelling in the face, lips, tongue, or throat, rapid heartbeat, fainting or dizziness, or problems breathing or swallowing.
  • Pancreatitis: Inflammation of the pancreas, which can cause severe abdominal pain, nausea, vomiting, and fever.
  • Hypoglycemia: Low blood sugar levels, which can cause symptoms such as sweating, dizziness, confusion, and fainting.
  • Acute kidney injury: A sudden and severe decline in kidney function, which can cause symptoms such as swelling, fatigue, and changes in urine output.
  • Diabetic retinopathy complications: May cause vision changes, including sudden vision loss, and blindness.
  • Thyroid cancer: Increased risk of developing thyroid cancer, especially if you have a history of thyroid cancer

The information above does not list all possible side effects. Contact your doctor or pharmacist if you experience any side effects not listed. You or your doctor may report side effects to the FDA by calling 1-800-FDA-1088.

Warnings & Precautions

Before using Rybelsus, tell your doctor or pharmacist:

  • If you are allergic to any medications such as Rybelsus
  • If you have thyroid cancer or have a family history of medullary thyroid carcinoma (MTC)
  • If you have kidney problems
  • If you have pancreatitis or have had pancreatitis
  • If you have gallbladder problems or a history of gallbladder problems
  • If you are pregnant or expect to become pregnant
  • If you are breastfeeding or plan to breastfeed

Pancreatitis

Taking Rybelsus can  cause your pancreas to swell and become inflamed resulting in pancreatitis. Signs of pancreatitis include back pain and severe stomach pain that causes you to throw up. Contact your doctor right away if you experience any symptoms that do not go away.

Thyroid Cancer

Taking Rybelsus increases your risk for a certain type of cancer known as medullary thyroid carcinoma (MTC). You should not take Rybelsus if you’ve had thyroid cancer or have a family history of thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN 2).

Kidney Problems

Taking Rybelsus can cause a worsening of kidney function, especially if you have pre-existing kidney disease or are taking medications that affect the kidneys such as ACE inhibitors. Signs of kidney failure include vomiting, nausea, and diarrhea. Contact your doctor if you experience any symptoms that do not go away.

Hypoglycemia

Taking Rybelsus may increase your risk of hypoglycemia, especially if taken in combination with other medications that lower blood sugar levels such as insulin. Signs of low blood sugar include sweating, confusion, headache, fast heartbeat, hunger, irritability, dizziness, blurred vision, and shaking. Contact your doctor if you experience any symptoms that do not go away.

Diabetic Retinopathy

Taking Rybelsus can increase your risk of complications with diabetic retinopathy. Your doctor will monitor your eyes regularly if you have a history of diabetic retinopathy.

Gallbladder Problems

Taking Rybelsus can increase your risk of developing gallbladder issues especially if you have a history of gallbladder problems. Signs of gallbladder problems include fever or chills, jaundice or yellowing of the skin, pain in your upper stomach, diarrhea, or abnormal stool and urine colors. Contact your doctor if you experience any symptoms that do not go away.

Gastroparesis

Taking Rybelsus may cause gastroparesis, a condition in which the stomach does not empty properly. If you have or have had a history of gastroparesis, do not take Rybelsus.

Pregnant or Planning to Become Pregnant

It is not known if Rybelsus affects the unborn child. If you are pregnant or plan to become pregnant while taking Rybelsus, talk to your doctor for the best course of action before taking Rybelsus.

Breastfeeding

It is not known if Rybelsus passes into breast milk. If you are breastfeeding or considering breastfeeding while taking Rybelsus, talk to your doctor for the best course of action before taking Rybelsus.

Interactions & Contraindications

Before using Rybelsus, tell your doctor or pharmacist if you take any medications, herbal supplements, or vitamins.

Insulin

Taking Rybelsus with insulin may increase your risk of hypoglycemia or low blood sugar. Do not take Rybelsus until you’ve consulted with your doctor to determine if change of therapy is needed.

Other Antidiabetic Medications

Taking Rybelsus with other antidiabetic medications may increase your risk of hypoglycemia or low blood sugar. Do not take Rybelsus until you’ve consulted with your doctor to determine if change of therapy is needed.

Warfarin

Taking Rybelsus with Warfarin can increase the effects of warfarin, a blood thinner medication, which can increase the risk of bleeding. Consult with your doctor to determine if change of therapy is needed.

Drugs that Affect the Gastrointestinal System

Taking Rybelsus with medications that affect the gastrointestinal system such as antibiotics or proton pump inhibitors (PPI), can affect the effectiveness of Rybelsus. Consult with your doctor to determine if change of therapy is needed.

Rybelsus Coupon & Pricing

Order Rybelsus Online from a Trusted Canadian Pharmacy

Managing diabetes effectively requires access to essential medications, and for many, the cost can be a significant barrier. Rybelsus, a leading medication for controlling blood sugar levels, is no exception. Prices in the United States can be particularly steep, making it challenging for patients to maintain their treatment regimen.

Pharma Giant is a prescription referral service which works with licensed and trusted Canadian pharmacy partners to ensure that American patients can buy Rybelsus without the financial strain associated with high retail prices.

US vs Canadian Medication Prices

The US prices listed in the table below are based on the current prices available on GoodRx, a popular resource for finding the best prices for medications in the United States. This comparison highlights the potential savings available to patients who choose to order Rybelsus through Pharma Giant.

Example of Savings on Rybelsus

Consider the cost savings for Rybelsus 3mg:

  • In the US (GoodRX): The price for 30 tablets of Rybelsus 3mg is approximately $1,114.
  • Through Pharma Giant: The same 30 tablets are available for just $297.

This example shows a significant saving opportunity, where patients can save over 70% when they purchase Rybelsus through Pharma Giant compared to average US retail prices. Such savings are not only beneficial for immediate financial relief but also ensure continued access to necessary medication for diabetes management.

StrengthQuantityCanada PriceUS PriceSavings (%)
3mg30 tabs$297$111473.3%
3mg60 tabs$570$224974.7%
3mg90 tabs$810$333875.7%
7mg30 tabs$305$111972.7%
7mg60 tabs$580$228074.6%
7mg90 tabs$855$342975.1%
14mg30 tabs$315$118873.5%
14mg60 tabs$610$235974.1%
14mg90 tabs$900$352974.5%

Rybelsus Coupon

Discount Code Special Offer: To further assist with managing healthcare expenses, Pharma Giant is offering an exclusive discount to purchase Rybelsus online. Use the coupon code RYBEL10 at checkout to receive a 10% OFF. This offer is valid for one use per customer, with a maximum savings of $50, and requires a minimum spend of $100.

By choosing Pharma Giant for your Rybelsus needs, patients in the US can significantly reduce the financial burden of their diabetes medication. This initiative ensures that essential treatments are more accessible, offering substantial savings especially for those without insurance coverage.

Rybelsus is taken orally once daily, preferably with water, on an empty stomach at least 30 minutes before the first meal of the day.

The active ingredient in Rybelsus is semaglutide.

Rybelsus may contain the following inactive ingredients: magnesium stearate, microcrystalline cellulose, povidone and salcaprozate sodium (SNAC).

Rybelsus works by stimulating the GLP-1 receptor, which helps to lower blood sugar levels.

No, Rybelsus is only indicated for use in adults with type 2 diabetes.

Rybelsus can start working within a few days of starting the medication.

Rybelsus can be taken with other diabetes medications, but it is important to discuss this with a healthcare provider first.

If a dose of Rybelsus is missed, it should be taken as soon as possible. If it is close to the time of the next scheduled dose, the missed dose should be skipped and the regular dosing schedule should be resumed.

No, Rybelsus should not be taken during pregnancy.

No, Rybelsus should not be taken while breastfeeding.

No, Rybelsus is not indicated for use in children.

Yes, Rybelsus can cause weight loss in some patients as a result of its effects on blood sugar control and appetite regulation.