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Serevent Diskus Salmeterol Xinafoate
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Salmeterol Inhaler (Generic) Salmeterol (Salmeterol Xinafoate)
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What is Serevent Diskus?

Serevent Diskus (salmeterol xinafoate) is a prescription inhaler used to help people with asthma, exercise-induced bronchospasm (EIB), and chronic obstructive pulmonary disease (COPD) breathe more easily.

It contains salmeterol, which is a type of long-acting bronchodilator (LABA).

Serevent Diskus doesn’t offer fast relief for sudden breathing issues, so it’s not a substitute for a rescue inhaler.

This medication is usually prescribed for adults and children aged 4 years and older.

However, it’s not recommended for people whose asthma is already well-controlled with other medications.

Additionally, if you have a severe allergy to milk proteins or any of the ingredients in Serevent Diskus, you should not use this medication.

How Does Serevent Diskus Work?

Serevent Diskus uses salmeterol, a long-acting bronchodilator, to target specific lung receptors called beta2-adrenoceptors.

These receptors are more responsive to salmeterol than other drugs, effectively relaxing the airway muscles.

This relaxation opens up the airways for easier breathing. Salmeterol also boosts cyclic AMP levels in lung cells, which helps prevent the release of substances triggering allergic reactions and inflammation, like histamines.

Overall, Serevent Diskus keeps airways open and lowers the risk of asthma attacks and breathing issues.

Dosage Information and Usage

Dosage Form and Strengths of Serevent Diskus

Serevent Diskus is available as an inhalation powder in a device containing a foil blister strip. Each blister contains 50 micrograms (mcg) of the active ingredient salmeterol. This medication is designed for oral inhalation only, meaning it is inhaled through the mouth directly into the lungs.

Usage

Before using Serevent Diskus, make sure you have been properly instructed by a healthcare provider on how to use it correctly.

If children are using the inhaler, they should do so under the supervision of an adult.

It’s important to follow the prescribed dosage exactly: for asthma and COPD, the usual dose is one inhalation twice daily, about 12 hours apart.

If you’re using it to prevent breathing difficulties caused by exercise, take one inhalation at least 30 minutes before exercising.

Do not use more than the prescribed amount or more frequently than directed.

Storage Information

Serevent Diskus should be stored at room temperature, between 68°F and 77°F (20°C and 25°C), and kept in a dry place away from direct heat or sunlight.

It’s important to keep the inhaler out of the reach of children.

The inhaler comes in a moisture-protective foil pouch and should remain inside this pouch until you are ready to use it for the first time.

Once the pouch is opened, the inhaler should be used within six weeks or discarded when the dose counter reads “0,” whichever comes first.

The inhaler is designed for single use and should not be taken apart or reused.

Side Effects

Common Side Effects

  • Headache
  • Nasal congestion
  • Bronchitis
  • Throat irritation
  • Runny nose
  • Flu
  • Musculoskeletal pain (for COPD)
  • Cough (for COPD)
  • Respiratory infection (for COPD)

Serious but Rare Side Effects

  • Sudden breathing problems immediately after using the inhaler
  • Increased blood pressure
  • Chest pain
  • Fast or irregular heartbeat
  • Tremors
  • Nervousness
  • Serious allergic reactions, such as rash, swelling of the face, mouth, and tongue, hives, and breathing problems
  • High blood sugar levels (hyperglycemia)
  • Low potassium levels (hypokalemia)

Warnings and Precautions

  • Asthma-Related Death: Using Serevent Diskus alone for asthma can increase the risk of asthma-related death. It should only be used with an inhaled corticosteroid (ICS) to manage asthma safely.
  • Pediatric and Adolescent Patients: Children and teenagers using Serevent Diskus are at risk of asthma-related hospitalizations. It’s safer to use a combination inhaler that includes both a LABA (like Serevent) and an ICS for these age groups.
  • Deterioration of Disease and Acute Episodes: Serevent Diskus should not be used during severe asthma or COPD flare-ups. It is not intended for immediate relief of acute symptoms. Use a rescue inhaler for sudden breathing problems.
  • Not a Substitute for Corticosteroids: Serevent Diskus does not have the anti-inflammatory effects of corticosteroids. Continue taking your prescribed corticosteroids even if you feel better with Serevent Diskus.
  • Excessive Use and Other LABAs: Do not use Serevent Diskus more often than prescribed or with other LABA medicines. Overuse can lead to serious side effects, including heart problems.
  • Paradoxical Bronchospasm: Inhalation of Serevent Diskus may cause a sudden worsening of breathing. If this happens, use a rescue inhaler and stop using Serevent Diskus immediately.
  • Cardiovascular and Central Nervous System Effects: Overuse of Serevent Diskus can lead to heart issues or nervous system effects like tremors or headaches. Use it cautiously if you have heart problems.
  • Immediate Hypersensitivity Reactions: Severe allergic reactions, including anaphylaxis, may occur. People with severe milk protein allergies should avoid Serevent Diskus.
  • Drug Interactions with Strong CYP3A4 Inhibitors: Avoid using Serevent Diskus with strong CYP3A4 inhibitors (like certain antifungals and antibiotics) to prevent increased cardiovascular side effects.
  • Coexisting Conditions: Use Serevent Diskus carefully if you have conditions like seizures or thyroid problems, as it may worsen these issues.
  • Hypokalemia and Hyperglycemia: Serevent Diskus can cause low potassium levels and high blood sugar in some patients. These effects are usually minor but should be monitored.

Overdosage

Taking too much Serevent Diskus can cause symptoms like:

  • seizures,
  • chest pain,
  • high or low blood pressure,
  • rapid or irregular heartbeats,
  • nervousness,
  • headaches,
  • tremors,
  • muscle cramps,
  • dry mouth,
  • palpitations,
  • nausea,
  • dizziness,
  • Fatigue,
  • trouble sleeping

It can also lead to dangerous heart rhythm changes and, in severe cases, cardiac arrest or death.

If an overdose occurs, stop using Serevent Diskus and seek medical help immediately.

Treatment includes stopping the medication, supportive care, and monitoring the heart.

A selective beta-blocker might be used carefully, but it can cause bronchospasm. Dialysis is not known to be helpful for overdose.

Drug Interactions With Other Medications

  • Inhibitors of Cytochrome P450 3A4: Using Serevent Diskus with strong CYP3A4 inhibitors (like ritonavir or ketoconazole) is not recommended. These drugs can increase the amount of Serevent Diskus in your system, which may lead to more side effects, such as heart problems.
  • Monoamine Oxidase Inhibitors and Tricyclic Antidepressants: Be very careful if you are taking monoamine oxidase inhibitors or tricyclic antidepressants, or if you have stopped them within the last two weeks. These drugs can enhance the effects of Serevent Diskus, possibly increasing its impact on the blood vessels.
  • Beta-adrenergic Receptor Blocking Agents: Beta-blockers can reduce the effectiveness of Serevent Diskus and might cause severe breathing problems. They are generally avoided in people with asthma or COPD, but if needed, only cardioselective beta-blockers should be used with caution.
  • Non–Non-Potassium-Sparing Diuretics: Taking Serevent Diskus with non–non-potassium-sparing diuretics (like loop or thiazide diuretics) can worsen changes in heart rhythm and lower potassium levels. Be cautious with this combination, especially if the dose of Serevent Diskus is higher than recommended.

Alternative Medications

Cost & Coupons

Serevent Diskus is a prescription inhaler that helps people with asthma, exercise-induced bronchospasm (EIB), and chronic obstructive pulmonary disease (COPD) breathe more easily. However, in the United States, the cost can be quite high, reaching $499.37 for a 5mcg/60 dose inhaler.

At Pharma Giant, we believe that essential healthcare should be accessible to everyone, regardless of cost.

We offer competitive pricing on Serevent Diskus to ensure you receive the care you need without the financial burden.

Check out our Serevent Diskus options:

  • 50mcg – 60 doses: $109.00
  • 50mcg – 120 doses: $212.00
  • 50mcg – 180 doses: $309.00

Quality medication at reasonable prices is our priority. Don’t allow financial constraints to compromise your health.

Exclusive Discount Code and Limited-Time Offer

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Simply enter the code PGSAVE10 at checkout to enjoy a 10% discount on your Serevent Diskus order.

This limited-time offer allows you to save on healthcare medications without compromising on quality. This offer is available for a one-time use per customer.

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Ordering Information

Serevent Diskus is available only with a valid prescription to ensure patient safety and compliance with medical standards. Patients can obtain up to a 90-day supply, which provides convenience for ongoing treatment and effective expense management.

Commitment to Quality and Timely Delivery

At Pharma Giant, we prioritize delivering premium medications with unmatched efficiency.

Our express shipping service guarantees that your orders arrive at your doorstep within just 3-5 business days throughout the United States.

We take every precaution to ensure the integrity of your medications during transit by using secure, protective packaging.

Why Choose Pharma Giant?

Partnering with Pharma Giant means choosing a reliable ally focused on improving your health and convenience. We are committed to providing you with high-quality products and services that meet your needs.

Frequently Asked Questions

Serevent Diskus is a prescription inhaler containing the active ingredient salmeterol, a long-acting beta-agonist (LABA). It is used to help prevent and control symptoms of asthma and chronic obstructive pulmonary disease (COPD), such as wheezing and shortness of breath.

The typical dosage of Serevent Diskus is one inhalation (50 mcg of salmeterol) twice daily, roughly 12 hours apart.

Serevent Diskus typically begins to work within 30 minutes after inhalation, with its effects lasting for about 12 hours.

Serevent Diskus (salmeterol) is primarily used for the following conditions:
  • Asthma: Used with an inhaled corticosteroid (ICS) to help manage symptoms.
  • Chronic Obstructive Pulmonary Disease (COPD): Helps improve breathing and prevent symptoms like wheezing and shortness of breath.
  • Exercise-Induced Bronchospasm: Prevents airway tightening that can occur during physical activity.

Serevent Diskus contains salmeterol, a long-acting bronchodilator. It works by relaxing the muscles around the airways, making breathing easier.

Store Serevent Diskus at room temperature, between 68°F and 77°F (20°C and 25°C). Keep it in a dry place away from direct heat and sunlight. The inhaler should remain in its moisture-protective foil pouch until you can use it. Once opened, use the inhaler within 6 weeks or by the time the dose counter reads “0,” whichever comes first. Keep out of reach of children.

To use Serevent Diskus, hold the inhaler and push the thumb grip to open it. Slide the lever until it clicks to load a dose. Breathe out fully, place the mouthpiece in your mouth, and inhale deeply. Hold your breath for 10 seconds, then exhale slowly. Close the Diskus and rinse your mouth with water, spitting it out to prevent oral thrush. Follow your doctor’s instructions and use only the prescribed dose.

Serevent Diskus is not a steroid. It is a long-acting beta-agonist (LABA) that works by relaxing the muscles around the airways to help you breathe more easily. Unlike steroids, you do not need to rinse your mouth after using Serevent Diskus.

For adults and children aged 4 years and older, Serevent Diskus is usually taken as one inhalation (50 micrograms) twice a day, with doses spaced at least 12 hours apart. For children younger than 4 years, the use and dose should be determined by a doctor.

The therapeutic effect of Serevent Diskus is to help ease breathing by relaxing the muscles around the airways. This relaxation allows air to flow more easily into the lungs.

Serevent Diskus provides 60 inhalations per inhaler.

Common side effects of salmeterol in Serevent Diskus include headache, throat irritation, and muscle pain. Serious but less common side effects can include increased heart rate, irregular heartbeat, high blood pressure, and allergic reactions such as rash or swelling.

Serevent Diskus can be used long-term, but it may increase the risk of asthma-related death. It’s important to use only the prescribed dose and duration as directed by your doctor.

No, Serevent Diskus cannot be your only inhaler for asthma. It should not be used alone without an inhaled corticosteroid (ICS). It is intended as an additional therapy for patients whose asthma is not well controlled by an ICS alone.

You may not taste, feel, or smell the dry powder when using Serevent Diskus. As long as you use the Diskus according to the instructions, you will still receive your full dose of medication.

Serevent Diskus is a preventer, not a reliever. It is used to prevent bronchospasm and manage asthma symptoms when used alongside an inhaled corticosteroid (ICS).

When taking Serevent Diskus, avoid using strong cytochrome P450 3A4 (CYP3A4) inhibitors, such as ritonavir, atazanavir, clarithromycin, and ketoconazole.

Yes, you can drink water after taking Serevent Diskus. It is recommended to rinse your mouth with water to help prevent hoarseness, throat irritation, and mouth infections. However, avoid swallowing the water after rinsing.

Before using Serevent Diskus, tell your doctor if you have any allergies, especially to milk proteins. Let them know if you have heart problems, such as high blood pressure or heart disease, or if you have a history of seizures or thyroid issues. Also, mention if you have diabetes or other conditions that affect blood sugar or potassium levels. Inform your doctor about all the other medicines you’re taking, including over-the-counter ones and supplements, especially if they include strong medications like ketoconazole or ritonavir.

If you overdose on Serevent Diskus, you may experience symptoms like rapid heartbeat, high or low blood pressure, headaches, tremors, or dizziness. In severe cases, it could lead to heart problems or even cardiac arrest. If you think you’ve taken too much, stop using the inhaler and seek medical help immediately.

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

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