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Tabrecta (Capmatinib)
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Tabrecta FCT Capmatinib
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What is Tabrecta?

Tabrecta (capmatinib) helps treat a type of lung cancer called non-small cell lung cancer (NSCLC). This cancer has spread to other parts of the body.

Tabrecta works for people whose cancer has a special change in their genes, which doctors can find with a test. This gene change makes the tumor grow differently, and Tabrecta helps to stop it from growing.

Tabrecta is a treatment only for adults, and it is not known if it is safe for kids. Your doctor will make sure it is the right medication for you, and they will help you with any questions about the Tabrecta dosing.

How Does Tabrecta Work?

Tabrecta targets a specific gene change in cancer cells called MET exon 14 skipping. This change causes the cancer cells to grow uncontrollably.

Usually, the MET gene helps control the growth of cells, but when it has this change, it makes the gene behave differently, allowing cancer to spread. Tabrecta blocks this problem by stopping the cancer cells from growing.

It works by targeting a special protein called MET, which is involved in the growth of these cancer cells. When the MET gene is changed, the protein becomes too active, helping cancer cells grow faster.

Tabrecta prevents this by blocking the protein’s action. This helps slow down the cancer and can stop it from spreading.

Dosing Information and Usage

To get the best results, follow the Tabrecta dosage instructions carefully.

You will typically take Tabrecta 200mg tablets twice daily, with or without food.

Do not break, crush, or chew the tablets; always take them as your doctor advises.

If you miss a dose or experience side effects, consult your doctor before changing your routine.

Dosage Form and Strengths of Tabrecta

Tabrecta comes in tablets that you swallow. Here are the different strengths of Tabrecta available:

  • Tabrecta 200mg tablet: Yellow, oval-shaped tablet with beveled edges.
  • Tabrecta 150mg tablet: Pale orange-brown, oval-shaped tablet with beveled edges.

How to Use Tabrecta?

  1. You should take Tabrecta 200mg tablets two times a day. You can take it with or without food, depending on what is most convenient for you.
  2. Do not break, crush, or chew the tablet. This helps ensure the medication works properly.
  3. If you forget to take Tabrecta, do not take an extra dose to make up for it. Just take your next dose at the scheduled time.
  4. Do not take another dose. Simply take your next dose as planned. Do not change your dose without first consulting your healthcare provider.

Tabrecta Side Effects

Tabrecta side effects may include lung or breathing, liver, and pancreas problems.

Some side effects can be severe and need immediate medical attention, while others may be more common and manageable.

Common Side Effects

  • Swelling of your hands or feet
  • Nausea
  • Muscle or bone pain
  • Tiredness or weakness
  • Vomiting
  • Trouble breathing
  • Cough
  • Loss of appetite
  • Changes in certain blood tests

Severe Side Effects

  • Lung or breathing problems: Inflammation of the lungs can lead to serious issues, including death. Seek immediate medical attention if you experience:
  • Cough
  • Fever
  • Trouble breathing or shortness of breath
  • Liver problems: TABRECTA may cause liver issues. Contact your doctor if you notice:
    • Yellowing of the skin or eyes (jaundice)
    • Dark urine
    • Light-colored stools
    • Confusion, tiredness, or loss of appetite
    • Nausea and vomiting
    • Pain or tenderness in the right side of your stomach
    • Weakness or swelling in the stomach area
  • Pancreas problems: High levels of amylase or lipase may indicate a problem with your pancreas. Contact your healthcare provider if you experience:
    • Upper stomach pain spreading to your back
    • Weight loss
    • Nausea or vomiting
  • Allergic reactions: Stop taking Tabrecta and consult your doctor immediately if you experience:
    • Fever or chills
    • Itching or rash
    • Dizziness or fainting
    • Nausea or vomiting

Warnings and Precautions

Some warnings and precautions when taking Tabrecta include lung, liver, and pancreas problems.

If you notice any signs of these, contact your doctor right away. It is also important to avoid too much sunlight while taking Tabrecta and make sure you are not pregnant before starting treatment.

Always follow your doctor’s advice to stay safe.

  • Lung problems: Tabrecta can cause serious breathing problems, which can be life-threatening. If you start having trouble breathing, a cough, or a fever, inform your doctor immediately. These could be signs of a lung condition called interstitial lung disease (ILD), which means inflammation or swelling in the lungs.
  • Liver problems: Taking Tabrecta can affect how your liver works. Your doctor will test your liver before you start treatment and while taking the medication. If your skin or eyes turn yellow, if your urine turns dark, or if you have pain in your stomach, get medical help immediately.
  • Pancreas problems: Tabrecta can cause problems with the pancreas, an organ that helps with digestion. If you feel pain in your stomach, especially after eating, and feel sick or lose weight, let your doctor know immediately.
  • Allergic reactions: Some people can have an allergic reaction to Tabrecta. This might cause symptoms like fever, rash, itching, or nausea.
  • Sunlight sensitivity: Tabrecta can make your skin more sensitive to sunlight, making you more easily sunburned. Be sure to wear sunscreen or protective clothing when you are outside.
  • Pregnancy warning: Tabrecta can harm an unborn baby, so if you are pregnant, think you might be pregnant, or plan to become pregnant, do not take this medication. Use birth control while using Tabrecta and for one week after you stop taking it to avoid harming a baby.

Drug Interactions With Other Medications

When you take Tabrecta with other medications, it can change how both drugs work. Some medications can make Tabrecta stronger, which can lead to more side effects.

Here are some of the Tabrecta drug interactions to know:

  • Strong CYP3A inhibitors: These can make Tabrecta stay in your body longer, causing more side effects. Your doctor will watch you closely if you’re taking both.
  • Strong and moderate CYP3A inducers: These can make Tabrecta weaker and less effective. Avoid taking Tabrecta with these drugs.
  • CYP1A2 drugs: If you take Tabrecta with a drug that is similarly processed by your body, it can make the other drug stronger, leading to more side effects. Your doctor may change the other drug’s dose.
  • P-glycoprotein (P-gp) drugs: Tabrecta can increase the levels of these drugs, which could cause more side effects. The dose of the other drug might need to be lowered.
  • Breast Cancer Resistance Protein (BCRP) drugs: Like P-gp drugs, Tabrecta can raise BCRP levels, worsening side effects. Your doctor may adjust the other drug’s dose.
  • MATE1 and MATE2K drugs: Taking Tabrecta with these drugs can increase their levels, too, possibly causing side effects. The dose of these drugs may need to be reduced.

Tabrecta Alternatives

Tabrecta alternatives include pembrolizumab, nivolumab, osimertinib, and more.

These options are available in case you are not reacting well to Tabrecta. However, make sure to contact your doctor before choosing an alternative yourself.

  • Keytruda (pembrolizumab)
  • Opdivo (nivolumab)
  • Tagrisso (osimertinib)
  • Alimta (pemetrexed)
  • Avastin (bevacizumab)
  • Imfinzi (durvalumab)

Order Tabrecta from Canada & SAVE

For patients looking for affordable access to life-saving medication, Pharma Giant offers Tabrecta at a budget-friendly cost in Canada.

The cost of Tabrecta can be high, making it difficult for some patients to get the treatment they need. However, with Pharma Giant, you can access Tabrecta Canada at prices up to 90% lower than what is typically found in the United States.

Our platform is designed to be simple and transparent, so you can easily see the total cost of Tabrecta upfront, eliminating any surprise charges.

In addition to competitive pricing, we offer bulk purchase options, allowing you to buy up to a 3-month supply of your medication at a reduced overall cost. This helps you save more and manage your treatment plan more effectively.

Ordering from Pharma Giant also saves you valuable time and effort. You no longer need to cross the border to access affordable medication. Our fast and reliable shipping delivers your medications directly to your doorstep in 3-5 business days.

With Pharma Giant, you get the life-saving medication you need at an affordable price, delivered with care right to your door. The Tabrecta cost should never be a barrier to your health.

How to Order Tabrecta Online?

  1. Search for Tabrecta on the website and click “Buy” to add it to your cart. If you need more medications, click “Continue shopping” to add them.
  2. Once you have everything in your cart, click “Continue Checkout” to move to the checkout page.
  3. Enter your contact, payment, and shipping information. If you are a new customer, create an account with your email and password to complete the process. Apply the promo code PGSAVE10 to save 10% on your first order.

Frequently Asked Questions

Tabrecta is a medication used to treat a type of lung cancer called non-small cell lung cancer (NSCLC). It helps stop the cancer cells from growing and spreading in the body.
Tabrecta blocks a specific protein called MET, which helps cancer cells grow. By stopping this protein, Tabrecta can slow down or stop the cancer from growing and spreading.
No, Tabrecta is not traditional chemotherapy. While traditional chemotherapy attacks cancer and healthy cells, Tabrecta targets only cancer cells.
Tabrecta does not usually cause hair loss. While hair loss can be a side effect of some cancer treatments, it is not a common side effect of Tabrecta.
Tabrecta starts working right away to slow down the growth of your cancer. However, if you respond well to the medication, it may take a few weeks before you notice that your tumors have become smaller or have stopped growing.
Tabrecta has shown effectiveness in treating non-small cell lung cancer (NSCLC). In studies, 5% of patients saw their tumors disappear completely, while 63% experienced a shrinkage in their tumors.

Tabrecta can cause decreased blood pressure in some people, along with other side effects like nausea and vomiting.
When taking Tabrecta, you should watch out for side effects like feeling sick or changes in blood pressure. It is important to use birth control while on the medication and for one week after finishing it. Tell your doctor if you have liver or kidney problems. Avoid using certain other medications that can affect how Tabrecta works.
Tabrecta can cause side effects like nausea, tiredness, swelling, and changes in liver function. Some people may experience loss of appetite, diarrhea, or shortness of breath. It can also cause skin reactions or swelling in the legs.

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

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We are committed to providing fair, competitive pricing on all medications. If you find a lower price on the same product at another verified Canadian online pharmacy, we’ll match it.

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Note: Price matching does not currently apply to Mounjaro® , Ozempic® or Saxenda®. However, this policy may be updated in the future.