What is Toujeo DoubleStar?
Toujeo DoubleStar comes as a prefilled pen that contains insulin glargine, a long-acting type of insulin. Insulin is a natural hormone that helps the body move sugar from the blood into the cells for energy.
People with diabetes may not make enough insulin or may not use it properly, which causes high blood sugar. Toujeo DoubleStar insulin works slowly and keeps its effect for up to 36 hours, which makes it suitable as a once daily injection.
Each Toujeo DoubleStar pen contains 300 units per milliliter of insulin glargine. This higher concentration means the pen delivers more units with fewer injections compared to other pens.
Many people find this option helpful when their daily dose requires larger amounts of insulin. Your doctor decides the Toujeo DoubleStar dose based on your personal needs, whether you have type 1 or type 2 diabetes. Children as young as 6 years old may also use this pen under medical guidance.
Some common side effects of taking Toujeo DoubleStar include redness, swelling, or mild pain at the injection site.
The most important side effect to watch out for is low blood sugar, also called hypoglycemia. Symptoms may include shaking, sweating, a fast heartbeat, or dizziness. Severe cases can cause seizures or loss of consciousness. If you notice unusual reactions, seek medical help right away.
The Toujeo DoubleStar pen must not be mixed with other insulins or placed in a syringe. It is designed for subcutaneous use, which means you inject it under the skin of the thigh, upper arm, or abdomen.
Doctors usually recommend giving the injection at the same time each day, morning or evening, to keep blood sugar steady. Always check the label before using the pen to avoid mix-ups with other types of insulin.
Indications and Benefits of Toujeo DoubleStar
Doctors prescribe Toujeo DoubleStar insulin to adults and children from 6 years old who need long-acting insulin to manage diabetes.
This pen steadily delivers insulin glargine for up to 36 hours, helping to keep blood sugar levels balanced throughout the day and night.
Your doctor chooses the right Toujeo DoubleStar dose based on your health needs and guides you on how to use the pen safely.
What Are the Benefits of Toujeo DoubleStar?
- Toujeo DoubleStar insulin works for up to 36 hours, so one daily injection keeps blood sugar steady for the entire day and night.
- Each Toujeo DoubleStar pen contains a concentrated dose of 300 units per milliliter, which means fewer injections for people who require higher insulin doses.
- The long-acting effect of Toujeo DoubleStar helps reduce spikes and drops in blood sugar, giving more predictable control compared to shorter-acting insulins.
- Doctors can prescribe the Toujeo DoubleStar dose for both type 1 and type 2 diabetes, making it useful for a wide range of people.
- The prefilled Toujeo DoubleStar pen is easy to use, and it avoids the need for vials and syringes. This design improves convenience in daily diabetes care.
- Consistent use of Toujeo DoubleStar insulin can lower the risk of diabetes complications that come from uncontrolled blood sugar, such as nerve problems, kidney issues, and vision damage.
- The pen supports flexible timing, as you can inject either in the morning or evening, as long as you follow a consistent schedule each day.
Fact Table
| Fact Category | Fact Details |
| Generic Name | Insulin glargine U-300 |
| Medication Class | Long-acting basal insulin, also called a human insulin analogue |
| Primary Use | Management of type 1 and type 2 diabetes in adults and children 6 years and older who need long-acting insulin support |
| Additional Benefit | Provides steady blood sugar control for up to thirty-six hours. The concentrated strength reduces injection volume. The Toujeo DoubleStar pen allows up to one hundred sixty units per injection, which helps people needing higher daily doses |
| Available Form | Prefilled Toujeo DoubleStar pen with three milliliters total or nine hundred units at a concentration of three hundred units per milliliter |
| Method of Administration | Subcutaneous injection, which means under the skin of the abdomen, thigh, or upper arm. It is not for intravenous use, not for use in a pump, and not for mixing with other insulins |
| Frequency | Once daily at the same time each day |
| Storage Instructions | Keep unused pens in a refrigerator at a temperature between two and eight degrees Celsius. Do not freeze. Keep them in the carton to protect them from light. After first use, keep the pen at room temperature below thirty degrees Celsius for up to six weeks. Do not place it back in the refrigerator after the first use. Discard the pen after this in-use period, even if some insulin remains inside |
| Pregnancy and Breastfeeding | Safety information is limited. Use only if clearly needed and under medical guidance. Always discuss with a healthcare provider before using during pregnancy or breastfeeding |
| Drug Interactions | The risk of low blood sugar increases when taken with other diabetes treatments such as mealtime insulin or sulfonylureas. It may also interact with a class of drugs called thiazolidinediones, such as pioglitazone, which can cause fluid retention. Your doctor may adjust doses when combining with other blood sugar-lowering treatments |
| Manufacturer | Sanofi |
How It Works
Toujeo DoubleStar insulin comes in a prefilled pen that delivers insulin glargine, a long-acting type of insulin.
When you inject Toujeo DoubleStar under the skin, it slowly releases insulin into the body for up to thirty-six hours. This steady release helps keep blood sugar levels balanced through the day and night.
It allows sugar from the blood to move into the cells where it can be used for energy. By keeping sugar levels in a healthy range, Toujeo DoubleStar insulin lowers the risk of sudden spikes or drops and supports better daily diabetes management.
Dosage
The right Toujeo DoubleStar dose depends on your health condition, blood sugar levels, and whether you are new to insulin or already using another type. Toujeo DoubleStar insulin is a long-acting insulin that comes in a higher capacity prefilled pen.
Each pen contains 900 units of insulin glargine at a strength of 300 units per milliliter. Your doctor will decide the right starting dose and adjust it based on your needs and glucose readings.
Never change your dose on your own, as this may raise the risk of low or high blood sugar.
What Dosage Strengths Does Toujeo DoubleStar Come In?
Toujeo DoubleStar comes only in one strength: 300 units per milliliter. Each prefilled pen contains 900 units in total and allows dosing in steps of 2 units.
With Toujeo DoubleStar, you can inject between 2 and 160 units at one time. This makes it suitable for people who need larger amounts of long-acting insulin in a single injection.
Dosage Chart
| Patient Group or Situation | Recommended Toujeo DoubleStar Dose | Notes |
| Adults new to insulin with Type 1 diabetes | About one-third to one-half of the total daily insulin needs is Toujeo DoubleStar. The rest comes from short-acting insulin at meals. | Full effect may take up to five days. The doctor will guide titration. |
| Adults new to insulin with Type 2 diabetes | 0.2 units per kilogram of body weight once daily | Dose may change based on glucose levels and response. |
| Switching from once daily long acting insulin | Start with the same dose of Toujeo DoubleStar | Adjustments may follow depending on blood sugar results. |
| Switching from Lantus (insulin glargine U100) | Start with the same dose, but many patients need a higher daily Toujeo DoubleStar dose for the same control. | Monitor closely during the first weeks. |
| Switching from twice daily long acting insulin | Start with 80 percent of the total daily dose | The doctor will adjust gradually to reach stable control. |
| Children with diabetes age six and above | The doctor calculates the dose individually | Not recommended for children under six years or for type 2 diabetes under age eighteen. |
Usage Guide
Using Toujeo DoubleStar correctly is important to keep your blood sugar in a healthy range. This long-acting insulin comes in a prefilled pen, which makes it easier to use at home.
How do you administer Toujeo DoubleStar?
- Always check your insulin pen before use. Make sure it is the correct medication, the pen is not damaged, and the insulin looks clear and free from particles.
- Read the patient guide and follow the instructions given by your doctor. If you are unsure, ask your healthcare provider to show you how to inject Toujeo DoubleStar.
- Use a new sterile needle every time you inject. Attach the needle securely to the pen, but do not overtighten.
- Perform a safety test by selecting four units and pressing the injection button until insulin appears. This confirms that the pen works properly.
- Set the dose counter to zero before selecting your Toujeo DoubleStar dose. Then adjust to your prescribed dose. If you cannot choose the full dose, split it into two injections.
- Inject Toujeo DoubleStar under the skin. Common injection areas are the stomach, thigh, or upper arm. Rotate injection sites to avoid skin problems.
- Push the needle fully into the skin, press the button until the window shows zero, and count to five to make sure the full dose is delivered.
- Remove the needle carefully after the injection and place it in a sharps container. Do not reuse needles.
- Take Toujeo DoubleStar once daily at the same time each day, or as instructed by your doctor.
Side Effects
Toujeo DoubleStar insulin can help control blood sugar, but like any medication, it may cause side effects. Some side effects are common, while others are rare but more serious.
Common side effects
- Low blood sugar (hypoglycemia)
- Weight gain
- Headache
- Fatigue
- Dizziness
- Blurred vision
- Shaking or tremors
- Hunger
- Night sweats
- Cold sweat
- Mood changes
- Trouble sleeping
Severe side effects
- Severe low blood sugar with confusion or loss of consciousness
- Severe allergic reaction with rash, swelling, or breathing problems
- Swelling in the legs or ankles
- Fast heartbeat
- Severe vision changes
- Seizures
- Injection site reactions such as pain, redness, itching, or skin thickening
- High blood sugar (hyperglycemia) with extreme thirst or frequent urination
- Diabetic ketoacidosis with nausea, vomiting, or fruity-smelling breath
Missed Dose
If you miss your Toujeo DoubleStar dose, take it as soon as you remember, as long as it is within a few hours. If too much time has passed, skip the missed dose and continue with your regular schedule.
Do not inject an extra dose to make up for the missed one. Using a reminder app or setting alarms can help you stay on track with your Toujeo DoubleStar insulin.
If you are unsure about what to do, contact your doctor or pharmacist for advice.
Overdose
Taking more than your prescribed Toujeo DoubleStar dose can cause dangerously low blood sugar. Signs of overdose may include sweating, shakiness, dizziness, fast heartbeat, confusion, blurred vision, or fainting. Severe cases can lead to seizures or loss of consciousness.
Storage Information
Toujeo DoubleStar prefilled pens should be stored properly to keep them effective and safe to use. Unopened pens should be kept in the refrigerator and protected from direct heat and light. Do not freeze the pens, and if one has been frozen, it should not be used.
Once opened, a pen can be stored at room temperature but not above 30 degrees Celsius and must be discarded after six weeks.
Keep the pens out of reach of children and never store them with a needle attached. Expired or unused pens should be disposed of in a sharps container.
Warnings
Toujeo DoubleStar is an effective insulin for managing diabetes, but it comes with important warnings and precautions. Knowing these will help you use the medication safely and avoid serious health problems.
- Changes in insulin regimen should not be made without medical supervision because altering the type, strength, or method of use can affect blood sugar control and lead to hypoglycemia or hyperglycemia.
- Switching to Toujeo may cause higher fasting blood sugar at first, and some people may require higher doses to achieve the same level of control.
- The full effect of Toujeo may take up to five days, so daily blood sugar monitoring is needed in the first weeks of treatment.
- Risk of hypoglycemia is significant with Toujeo, and this can cause seizures, fainting, or even death if not treated quickly.
- Activities that require focus, such as driving or operating machinery, can be dangerous if low blood sugar happens because it affects reaction time and concentration.
- Medication errors can occur if Toujeo DoubleStar is mistaken for another type of insulin, so always check the label before use.
- Toujeo must not be drawn into a syringe from the prefilled pen because this may result in a dangerous overdose.
- Insulin use may lower potassium levels in the body, which can cause serious problems such as irregular heartbeat or muscle weakness.
- Taking Toujeo with medications called PPAR gamma agonists, such as thiazolidinediones, can cause fluid retention that may worsen heart failure.
- People with liver or kidney problems should tell their doctor, since they may need different insulin doses.
- Pregnancy changes insulin needs because requirements often drop in the first trimester and rise late, so close monitoring is important.
- It is unknown if insulin glargine passes into breast milk, and nursing mothers should ask their doctor for guidance.
- Toujeo pens are for single patient use and should never be shared to avoid the risk of spreading infections.
Boxed Warning and Precautions for Toujeo DoubleStar
| The most serious warning with Toujeo DoubleStar is the risk of severe hypoglycemia. Low blood sugar is the most common and dangerous side effect of insulin therapy, and it can cause seizures, fainting, coma, or even death if left untreated. People using Toujeo must check their blood sugar regularly, learn how to recognize early signs of hypoglycemia, and follow medical instructions carefully to reduce this risk. |
Contraindications
Toujeo DoubleStar should not be used by people who are experiencing low blood sugar episodes. It is also not suitable for anyone who has had an allergic reaction to insulin glargine or to any of the ingredients included in the Toujeo DoubleStar formulation.
Using it in these situations can be unsafe and may lead to serious health problems.
Interactions
- Insulin
- Metformin
- Glyburide
- Rosiglitazone
- Canagliflozin
- Dulaglutide
- Liraglutide
- Prednisone
- Danazol
- Niacin
- Androgens
- Birth control pills
- Ethinyl estradiol
- Clozapine
- Olanzapine
- Quetiapine
- Risperidone
- Citalopram
- Fluoxetine
- Tramadol
- Vorinostat
- Tacrolimus
- Quinine
- Clarithromycin
- Norfloxacin
- Ofloxacin
- Sulfamethoxazole
- Sulfadiazine
- Furosemide
- Hydrochlorothiazide
- Epinephrine
- Propranolol
- Atenolol
- Metoprolol
- Pindolol
- Sotalol
- Disopyramide
- Octreotide
- Pasireotide
- Pegvisomant
- Ledipasvir
- Sofosbuvir
- Moclobemide
- Phenelzine
- Rasagiline
- Selegiline
- Tranylcypromine
Cost & Coupons
Cost and Savings on Toujeo DoubleStar
If you are looking to buy Toujeo DoubleStar at a fair price, Pharma Giant makes it simple and affordable. We connect you with trusted Canadian pharmacies so you can access the treatment you need without overspending.
Many customers find that the Toujeo DoubleStar cost through our service is far less than what they usually pay in the United States.
When you buy Toujeo DoubleStar online from Canada, you get:
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- Careful handling of temperature-sensitive items.
Discounts for Toujeo DoubleStar Canada Orders
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Pharma Giant’s Guarantee
At Pharma Giant, your health, safety, and savings come first. We work only with licensed Canadian pharmacies to give you quality medications at prices lower than what you pay in the United States.
You can even order a 3-month supply to save more. Your prescriptions are always doctor-approved and pharmacist-verified. We never ship anything without making sure it is safe, authentic, and right for you.
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Frequently Asked Questions
Disclaimer
Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.
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