Trelegy Ellipta
from$189.99
$712
Trelegy Ellipta Fluticasone Furoate, Umeclidinium Bromide, Vilanterol Trifenatate
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Trelegy Ellipta Fluticasone Furoate, Umeclidinium Bromide, Vilanterol Trifenatate
Select product strength & quantity:
Prescription Required
Ships within 4-10 Business Days
Express Ships from Canada
Product of Canada
from$139.99
$712
Trelegy Ellipta Fluticasone Furoate, Umeclidinium Bromide, Vilanterol Trifenatate
Select product strength & quantity:
Prescription Required
Ships within 4-10 Business Days
Express Ships from Canada
Product of Canada

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TRELEGY10

What is Trelegy Ellipta?

Trelegy Ellipta is a prescription medication used for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD) and asthma in adults aged 18 and older who are not adequately controlled on other controller medications.

Trelegy Ellipta combines three active ingredients to help improve lung function and control symptoms.

Trelegy Ellipta is not a rescue inhaler and should not be used to relieve sudden breathing problems.

Trelegy Ellipta is not for children under 18, and studies have not established its safety in children. However, it provides an important treatment option for managing COPD and asthma effectively.

How Does Trelegy Ellipta Work?

Trelegy Ellipta combines three active ingredients: fluticasone furoate, umeclidinium, and vilanterol.

Each ingredient plays a unique role in treating COPD and asthma symptoms.

  • Fluticasone Furoate is a corticosteroid that reduces inflammation in the airways. It helps prevent inflammation by blocking certain chemicals in the body, which can reduce swelling and irritation in the lungs. This action helps improve breathing and manage symptoms of COPD and asthma.
  • Umeclidinium is an anticholinergic, which helps relax the muscles around the airways. By blocking specific receptors in the lungs, umeclidinium helps open the airways, making breathing easier.
  • Vilanterol is a long-acting beta-agonist (LABA) that relaxes the muscles in the airways, allowing them to open up and improve airflow. This ingredient helps with breathing over a long period.

These ingredients control symptoms, reduce inflammation, and make breathing easier for individuals with COPD and asthma. However, Trelegy Ellipta does not relieve sudden breathing problems and should not replace a rescue inhaler.

Dosage Information and Usage

Dosage Form and Strengths of Trelegy Ellipta

Trelegy Ellipta is available in two strengths:

  • 100/62.5/25 mcg per actuation: For some patients’ COPD treatment and asthma management.
  • 200/62.5/25 mcg per actuation: For more severe asthma cases or patients requiring an increased dose.

Each inhaler contains 30 once-daily doses, each delivering a combination of fluticasone furoate, umeclidinium, and vilanterol.

Recommended Dosage for Maintenance Treatment of Chronic Obstructive Pulmonary Disease (COPD)

The recommended dosage of Trelegy Ellipta for the maintenance treatment of COPD is one inhalation of 100/62.5/25 mcg once daily.

It is important to take Trelegy Ellipta at the same time every day. If you experience shortness of breath between doses, use a short-acting beta2-agonist (like albuterol) for immediate relief.

Recommended Dosage for Maintenance Treatment of Asthma

For the maintenance treatment of asthma, the starting dosage of Trelegy Ellipta depends on the severity of your asthma and other factors like previous treatments:

  • The starting dosage is Trelegy Ellipta 100/62.5/25 mcg once daily or 200/62.5/25 mcg once daily, as your healthcare provider prescribes.
  • The highest recommended dosage is one inhalation of 200/62.5/25 mcg once daily. This strength is not approved for COPD.
  • If you do not experience adequate relief with the 100/62.5/25 mcg dosage, your doctor may increase it to 200/62.5/25 mcg once daily. If this dosage does not adequately control your asthma, your doctor will evaluate your treatment plan and consider other options.

How to Use Trelegy Ellipta?

To use Trelegy Ellipta, follow these steps:

  1. Open the cover to prepare the dose. You should hear a click, signaling that the inhaler is ready. Do not open the inhaler until you are prepared to use it.
  2. Breathe out fully, away from the mouthpiece.
  3. Place the mouthpiece between your lips, ensuring a firm seal, and take a long, deep breath in. Do not block the air vent with your fingers.
  4. After inhaling, hold your breath for 3 to 4 seconds, then breathe out slowly.
  5. Slide the cover back over the mouthpiece.
  6. Rinse your mouth with water and spit it out to reduce the risk of side effects like thrush.

Storage Information

Store Trelegy Ellipta at room temperature, away from moisture and heat.

To protect the inhaler from humidity, keep it in its original packaging until you are ready to use it. Do not store the inhaler in the bathroom or any high-moisture areas.

Keep the inhaler out of children’s reach. Dispose of the inhaler after use, as each inhaler contains 30 blisters (or 14 for the institutional pack).

Check the expiration date on the package and avoid using the inhaler past that date.

Side Effects

Common side effects of Trelegy Ellipta include headaches, sore throats, and coughs. Severe side effects may involve serious reactions like pneumonia, eye problems, and allergies.

It is essential to monitor for any symptoms and consult with your doctor if they occur.

Common Side Effects

  • Upper respiratory tract infections
  • Sore throat and runny nose
  • Bronchitis
  • Constipation
  • Headache
  • Painful and frequent urination (signs of a urinary tract infection)
  • Nausea, vomiting, and diarrhea
  • Back pain
  • Mouth and throat pain
  • Hoarseness
  • Flu-like symptoms
  • Inflammation of the sinuses
  • Taste disturbances

Severe Side Effects

  • Fungal infection in mouth or throat (thrush)
  • Increased mucus production or change in color
  • Chills, fever, or coughing with increased breathing problems (signs of pneumonia)
  • Sudden breathing problems immediately after inhalation
  • Serious allergic reactions (rash, swelling, trouble breathing)
  • Increased blood pressure, chest pain, fast or irregular heartbeat
  • Eye problems, including glaucoma or cataracts
  • Bone thinning or weakness (osteoporosis)
  • Urinary retention (difficulty or painful urination)
  • Adrenal insufficiency (fatigue, weakness, low blood pressure)
  • Changes in blood values (high blood sugar, low potassium levels)
  • Slowed growth in children

Warnings and Precautions

Trelegy Ellipta can cause serious health risks in some individuals, so it is important to be aware of specific warnings and precautions when using this medication.

It may increase the risk of asthma-related deaths, pneumonia, and other complications, such as eye problems and bone thinning.

Always follow your healthcare provider’s advice and monitor for any side effects.

  • Increased Risk of Asthma-Related Deaths: Trelegy Ellipta contains vilanterol, which can increase the risk of asthma-related deaths, especially in children and adolescents.
  • Deterioration in COPD: Do not use Trelegy Ellipta for sudden worsening of chronic obstructive pulmonary disease (COPD). It is not for acute bronchospasm.
  • Interactions with Other Beta2-Agonists: Do not combine Trelegy Ellipta with other long-acting beta2-agonists like salmeterol or formoterol.
  • Oral Candida Infection: Rinse your mouth after using Trelegy Ellipta to reduce the risk of mouth and throat infections (thrush).
  • Acute Asthmatic Deterioration: Trelegy Ellipta should not be used for acute asthma attacks as it does not have immediate bronchodilator effects.
  • Immunosuppression: Trelegy Ellipta can weaken the immune system, increasing the risk of infections like tuberculosis or chickenpox.
  • Increased Risk of Pneumonia: People with COPD are at a higher risk of developing pneumonia while using Trelegy Ellipta.
  • Adrenal Insufficiency: Switching from oral steroids to Trelegy Ellipta may cause adrenal insufficiency, a condition where your body can not produce enough steroid hormones.
  • Bone Mineral Density Reduction: Long-term use may reduce bone density, raising the risk of fractures.
  • Paradoxical Bronchospasm: Trelegy Ellipta can rarely cause sudden breathing problems. If this occurs, use a fast-acting inhaler and stop the Trelegy Ellipta.
  • Eye Problems: Inhaled steroids can increase eye pressure, leading to conditions like glaucoma or cataracts.
  • Eosinophilia and Churg-Strauss Syndrome: In rare cases, long-term use can increase a type of white blood cell (eosinophils) and trigger Churg-Strauss Syndrome, an inflammatory condition.
  • Cardiovascular Risk: Trelegy Ellipta may affect heart rate and blood pressure, especially in people with heart disease.
  • Urinary Retention: The anticholinergic effect of Trelegy Ellipta can cause difficulty urinating, especially in men.
  • Special Populations: Use caution in pregnant or breastfeeding women and children under 18. Monitor patients with liver, kidney, or heart issues.

Drug Interactions With Other Medications

Trelegy Ellipta can interact with various medications, which may affect how the drug works or increase the risk of side effects.

It is important to be aware of potential drug interactions and discuss them with your healthcare provider before starting Trelegy Ellipta.

  • Antifungals: Itraconazole, Ketoconazole, Voriconazole
  • Antiretrovirals: Ritonavir, Atazanavir, Indinavir
  • Antibiotics: Clarithromycin, Telithromycin
  • Antidepressants: Nefazodone
  • Other long-acting beta2-agonists
  • Loop diuretics
  • Non-selective beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors
  • Tricyclic antidepressants
  • Anticholinergics

Alternative Medications

Suppose Trelegy Ellipta is unsuitable for you, or you are looking for other treatment options, several alternative medications may help manage chronic obstructive pulmonary disease (COPD) and asthma symptoms.

Unlike Trelegy, most alternatives are dual-drug combinations (LABA/ICS or LABA/LAMA). Trelegy is the only once-daily triple therapy available as a single inhaler.

Buy Affordable Drugs Online from Pharma Giant

Pharma Giant offers a convenient and budget-friendly solution for purchasing Trelegy Ellipta in Canada. We offer Trelegy Ellipta for only $189.95 compared to the average U.S. retail price of $332.

With us, you can save even more on your treatment with the added benefit of bulk discounts and exclusive coupon codes.

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How to Order Trelegy Ellipta Online?

Ordering Trelegy Ellipta in Pharma Giant online is simple and convenient. Follow these easy steps:

  1. Use the search field at the top of the website to find Trelegy Ellipta. Once you have selected the correct medication and dosage, click the ‘Buy’ button to add it to your cart. You can also search for other medications or products you need and add them to your cart.
  2. Enter your contact details, payment information, and shipping address to proceed through the secure checkout process. If you are a returning customer, log in with your email and password to speed up the process. After completing your order, you will receive a confirmation email with your payment and order details.
  3. For Trelegy Ellipta, you must upload a scanned copy or clear prescription photo. You can upload it directly on the website using the RX document uploader tool or fax it to 1-888-562-8159.

Bonus: Save 10% on your first order with coupon code PGSAVE10

Frequently Asked Questions

Trelegy Ellipta treats chronic obstructive pulmonary disease (COPD) by improving breathing and reducing flare-ups. It also prevents and controls asthma symptoms in adults.

Trelegy Ellipta contains three active ingredients: fluticasone furoate, umeclidinium, and vilanterol. Fluticasone furoate is a corticosteroid that helps reduce inflammation in the lungs. Umeclidinium is an anticholinergic that helps relax the muscles around the airways to improve breathing. Vilanterol is a long-acting beta2-agonist that relaxes the muscles in the airways, making breathing easier.

No, Trelegy Ellipta is not a rescue inhaler. It is a once-daily maintenance treatment designed to help manage asthma and COPD symptoms over time. It does not provide immediate relief for sudden breathing difficulties.

Before using Trelegy Ellipta, tell your doctor if you have heart problems, high blood pressure, diabetes, thyroid issues, glaucoma, or if you are pregnant or breastfeeding. Inform them about any allergies, infections, or if you have prostate or bladder issues. Also, share all medications you take, including prescriptions, over-the-counter drugs, vitamins, and supplements, as Trelegy may interact with them.

Doctors do not usually recommend using Trelegy Ellipta during pregnancy. Talk to your doctor if you are pregnant or planning to become pregnant before using it.

The best time to take Trelegy Ellipta is once daily, at the same time every day. Use it only once every 24 hours and rinse your mouth with water after inhalation (breathing in the medication through the inhaler) to reduce the risk of oropharyngeal candidiasis (a fungal infection in the mouth and throat).

Store Trelegy Ellipta in a dry place at room temperature, between 59°F and 86°F (15°C and 30°C). Keep it in its sealed pouch until you are ready to use it. Do not store it in the bathroom or any damp areas. Keep the inhaler away from heat, moisture, and direct sunlight. Keep it out of the reach of children.

To use the Trelegy Ellipta inhaler, open it by sliding the cover down. Then, breathe out fully away from the inhaler. Place the mouthpiece between your lips, close them around it, and inhale deeply and steadily. After inhaling, hold your breath for a few seconds, then breathe out. Close the inhaler and rinse your mouth with water to help prevent side effects like mouth infections. Use the inhaler once daily, at the same time each day.

Yes, Trelegy Ellipta is effective for asthma. It is a long-term maintenance treatment that helps prevent and control asthma symptoms in adults, improving breathing and reducing wheezing.

Yes, Trelegy Ellipta contains bronchodilators. The active ingredients, umeclidinium and vilanterol, help open the airways and improve breathing.

Trelegy Ellipsta stays in the body within three days of the last dose.

Disclaimer

Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.

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Price Match Guarantee

Price Match Guarantee

We are committed to providing fair, competitive pricing on all medications. If you find a lower price on the same product at another verified Canadian online pharmacy, we’ll match it.

Eligibility Criteria

  • The pharmacy must be a licensed Canadian online pharmacy with a verifiable address.
  • The competitor’s price must be current and active (not from a past or future promotion).
  • The product must be identical in strength, pack size, quantity, manufacturer, and country of origin.
  • Requests must be submitted before placing an order — adjustments cannot be made after purchase.
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Note: Price matching does not currently apply to Mounjaro® , Ozempic® or Saxenda®. However, this policy may be updated in the future.
Kenneth Fill, PharmD, MBA Fill

Kenneth Fill, PharmD, MBA, is a clinical pharmacist specialist and medical writer with a strong background in ambulatory care, pharmacogenomics, and medical content development. Based in the state of Michigan, he provides expert guidance on chronic disease state management. Kenneth completed his PharmD and MBA at the University of Toledo and pursued post-graduate residency training in ambulatory care and community-based pharmacy. His diverse background also includes academic detailing, clinical education, and interdisciplinary collaboration to enhance patient outcomes.