
What is Trulance?
Trulance (plecanatide) is a tablet taken orally that is used in adults to treat two types of chronic constipation. These are chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C).
Chronic idiopathic constipation means you have constipation for a long time, and the cause is not known. IBS-C is a condition where your belly hurts, you feel bloated, and you have constipation regularly.
Do not take Trulance if you have a bowel blockage (also called intestinal obstruction).
Trulance is also not safe for children under 6 years old because it may cause serious dehydration. It is also not recommended for children between 6 and 18 years old.
If you are pregnant, breastfeeding, or planning to become pregnant, talk to your doctor before starting Trulance. Also, let your doctor know about all other medicines, supplements, or vitamins you take.
How Does Trulance Work?
Trulance helps treat certain types of long-lasting constipation in adults. When you are constipated, it means that food moves too slowly through your digestive tract. This can cause your stool to become hard and dry, which can be painful and difficult to pass.
Trulance mimics a natural protein in your body. It attaches to specific spots in your small intestine and pulls more water into your gut.
This process softens your stool, making it easier to pass. It also promotes more regular and comfortable bowel movements.
Some people start feeling better as early as one week after taking Trulance.
Trulance Dosage and Administration
Trulance dosing is typically one tablet per day, taken with or without food.
You can take Trulance tablets whole or crushed for people who have trouble swallowing. The Trulance max dose is 3 mg per day, which is also the standard dose for both conditions.
Dosage Form and Strengths of Trulance
Trulance comes as a white to off-white round tablet. Each tablet contains 3 mg of the active ingredient. This is the only strength available.
How to Take Trulance?
- Take one tablet orally once daily.
- You can take it with or without food.
- Swallow the tablet whole with water.
- If you cannot swallow tablets, you can:
- Crush the tablet and mix it with one teaspoon of room-temperature applesauce.
- Mix the crushed tablet in 30 mL of room-temperature water and drink right away.
- Administer the crushed tablet with water through a nasogastric or gastric feeding tube.
- Do not store any mixture for later use.
- If you miss a dose, skip it and take the next dose at your usual time.
- Do not take two doses at the same time.
Recommended Trulance Dosage
Trulance dosage for chronic idiopathic constipation (CIC):
The usual Trulance dose for adults with CIC is 3 mg once daily. This dosage is the full Trulance dosing amount and also the Trulance max dose.
Take it around the same time each day to keep the medication working well in your body. You do not need to take it with food.
Trulance dosage for irritable bowel syndrome with constipation (IBS-C):
For adults with IBS-C, the recommended Trulance dosage is also 3 mg once daily. This dose helps improve regular bowel movements and reduce stomach discomfort.
Like with CIC, you can take this dose with or without food, and it should be taken at the same time each day.
Trulance Side Effects
Trulance may cause both mild and serious side effects in some people. The most common Trulance side effect is diarrhea, which can sometimes be severe and may start within the first few weeks of treatment.
Other side effects of Trulance can include nausea, bloating, and dizziness. Although rare, serious side effects of Trulance, like severe diarrhea or allergic reactions, can happen and should be treated right away.
If you notice any unusual symptoms while taking Trulance, contact your doctor for guidance.
Common Side Effects
Here are some mild or common side effects that some people may experience:
- Mild diarrhea
- Feeling bloated or having stomach tenderness
- Dizziness
- Nausea
- Cold symptoms like a stuffy nose or sore throat
- Urinary tract infections
Severe Side Effects
Though not common, serious side effects can occur and may need immediate medical help:
- Severe diarrhea
- Signs of dehydration (such as feeling very thirsty, dry mouth, or less urine)
- Allergic reaction (such as rash, swelling, or trouble breathing)
- Dangerous dehydration in children (Trulance is not safe for anyone under 6 years old)
If you experience any serious side effects from Trulance, stop using the medication and contact your doctor immediately.
Warnings and Precautions for Trulance
Trulance is not approved for children under 18. Do not use it in children younger than 6 years old because it may cause dangerous dehydration.
People with a blockage in the stomach or intestines should also avoid Trulance. In some cases, Trulance can lead to severe diarrhea.
You should be aware of how your body reacts once you start using it. Always consult your doctor if you have any existing health conditions. Talk to your doctor if you are pregnant or breastfeeding.
- Children under 6 years old should not use Trulance due to the risk of serious dehydration.
- Healthcare providers do not recommend Trulance for individuals between 6 and 18 years old because its safety in this age group has not been proven.
- Do not take Trulance if you have a known or suspected blockage in your intestines.
- Severe diarrhea may happen during treatment and can lead to dehydration, especially in the first few weeks.
- If severe diarrhea occurs, stop taking Trulance and contact your doctor right away.
- Let your doctor know if you are pregnant or planning to become pregnant. It is not clear if Trulance is safe during pregnancy.
- If you are breastfeeding or plan to breastfeed, talk to your doctor before using Trulance.
- Inform your doctor about any other medications, supplements, or over-the-counter products you are currently taking before starting Trulance.
- Do not take Trulance if you have ever had an allergic reaction to it or any of its ingredients.
Trulance Drug Interactions
Trulance is not known to have interactions with other drugs, foods, or supplements based on clinical trials. However, this does not mean Trulance interactions can never happen. Everyone responds to treatments differently.
Trulance Alternatives
If Trulance does not work well for you or causes side effects, there are other options that may help.
Some of these options are used for chronic idiopathic constipation, while others are used for irritable bowel syndrome with constipation. Your doctor can help you choose the best alternative to Trulance based on your condition, symptoms, and overall health.
Here are some of the Trulance alternatives to consider:
- Linzess (linaclotide)
- Amitiza (lubiprostone)
- Motegrity (prucalopride)
- Tegaserod (tegaserod)
- MiraLAX (polyethylene glycol 3350)
- Dulcolax (bisacodyl)
- Senokot (senna)
- Magnesium Citrate
- Generlac (lactulose)
- Colace (docusate)
- Citrucel (methylcellulose)
- Metamucil (psyllium)
Order Trulance Online and SAVE Big
Living with chronic constipation or IBS-C can be uncomfortable enough, and with this alone, you should not have to worry about how much your treatment will cost.
If you are searching for the best Trulance price or want to lower your out-of-pocket Trulance cost, Pharma Giant is here to help you access real savings without the stress. You may also qualify for a Trulance coupon to help make your treatment even more affordable.
Many Americans pay more than they should for prescription treatments. With Pharma Giant, you get reliable service, transparent pricing, and genuine Trulance from licensed Canadian pharmacies.
Why choose Pharma Giant?
- Affordable Trulance pricing with no hidden costs
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- Great customer support to guide you every step of the way
Do not let high prices stand between you and your health. Order Trulance through Pharma Giant and enjoy trusted service and real savings made just for you.
How to Order Trulance Online?
- Search for Trulance, select your dosage, and click Buy to add it to your cart.
- Enter your name, shipping address, and payment info at checkout. Use code PGSAVE10 for 10% off your first order.
- Upload your prescription online, email it to info@pharmagiant.com, or fax it to 1-888-562-8159
Frequently Asked Questions
Disclaimer
Pharma Giant provides medical information to help you better understand medications and medical conditions.This content is for informational use only and does not replace advice from a licensed medical practitioner. Consult your doctor or pharmacist before starting or changing any medication. All our partners follow strict safety standards set by their country’s health authorities to make sure you receive safe and high-quality medications.





