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Votrient
Votrient
Pazopanib Hydrochloride
Select product strength & quantity:

Prescription Required.

Product of Canada.

Shipped from Canada.

Prescription Required.Product of Canada.Shipped from Canada.

What is Votrient (pazopanib)?

Votrient is a brand name for the drug Pazopanib, which is used for the treatment of certain types of cancers, such as advanced renal cell carcinoma (a type of kidney cancer) and soft tissue sarcoma (a type of cancer that affects the body’s connective tissues). It belongs to a class of medications called tyrosine kinase inhibitors, which work by blocking the action of certain proteins that promote the growth and spread of cancer cells. Votrient is typically prescribed by a doctor and is available in tablet form.

What are the Indications for Votrient?

Votrient is indicated for the treatment of several types of cancer, including advanced renal cell carcinoma (kidney cancer) and soft tissue sarcoma, a type of cancer that forms in soft tissues like muscles or tendons.

How is Votrient used?

Storage

Votrient should be stored at room temperature between 68° – 77°F(20° – 25°) in its original container, away from light and moisture.

Keep out of reach of children and pets.

Instruction

Votrient should be taken once per day with or without food, at the same time every day to maintain a consistent level of medication in your body. Swallow the tablets whole with a glass of water. Do not crush, chew, or break the tablets.

Dosage

Votrient is available in tablet form in the strength of 200 mg.

The recommended dose is 800 mg or three tablets once per day.

Side Effects

It’s important to understand that although Votrient is FDA-approved, it comes with side effects that may or may not affect you.

Before starting Votrient, you should discuss possible side effects with your doctor or pharmacist.

Common Side Effects

Not all side effects require medical attention. As your body adjusts to Votrient, side effects may go away.

Tell your doctor if you experience the following symptoms, and they become severe or do not go away on their own:

  • Feeling tired or fatigue
  • Diarrhea
  • Nausea
  • Vomiting
  • Loss of appetite
  • Stomach pain
  • Headache
  • High blood pressure
  • Abnormal liver function

Serious Side Effects

Severe adverse reactions while using Votrient can occur. Seek emergency medical care or call 911 if you experience any of the following symptoms:

  • Severe allergic reaction: severe rash or itching, swelling in the face, lips, tongue, or throat, rapid heartbeat, fainting or dizziness, or problems breathing or swallowing.
  • Bleeding: unusual bleeding including nosebleeds, bleeding gums, or blood in urine or stool.
  • Blood clots: swelling, pain, or redness in the arm or leg, chest pain, or shortness of breath.
  • Heart problems: shortness of breath, chest pain, or fainting that could lead to heart attack or heart failure.

The information above does not list all possible side effects. Contact your doctor or pharmacist if you experience any side effects not listed. You or your doctor may report side effects to the FDA by calling 1-800-FDA-1088.

Warnings & Precautions

Before using Votrient, tell your doctor or pharmacist:

  • If you are allergic to any medications such as pazopanib
  • If you have a history of high blood pressure
  • If you have kidney problems
  • If you have liver problems
  • If you have a thyroid disorder
  • If you have had surgery recently
  • If you are pregnant or expect to become pregnant
  • If you are breastfeeding or plan to breastfeed

Excessive bleeding

Taking Votrient may result in unusual or excessive bleeding. If you experience unusual bleeding, such as nosebleeds, bleeding gums, or blood in the urine or stool, contact your doctor immediately.

Hyperthyroidism

Votrient may cause hypothyroidism, which is a condition where the thyroid gland does not produce enough hormones. Signs of hypothyroidism include fatigue, weight gain, cold intolerance, and constipation. If you experience any of these symptoms, contact your doctor.

Lung problems

Votrient may cause lung problems, including interstitial lung disease, which can be life-threatening. Symptoms of interstitial lung disease include coughing, shortness of breath, and chest pain. If you experience any of these symptoms, seek medical attention immediately.

Liver problems

Votrient may cause liver problems, including hepatitis, liver failure, and liver damage. Signs of liver problems include yellowing of the skin or eyes, dark urine, abdominal pain, and nausea. If you experience any of these symptoms, contact your doctor immediately.

High blood pressure

Votrient can sometimes cause high blood pressure. This can lead to health problems like heart attacks, strokes, and kidney damage. Your doctor will monitor your blood pressure regularly while you are taking it and may prescribe medication to help lower it if needed.

Heart problems

Taking Votrient may cause heart problems, such as heart failure or a heart attack. If you experience symptoms such as chest pain, shortness of breath, or fainting, seek medical attention immediately.

Blood clots

Votrient may increase the risk of blood clots, which can be life-threatening. Signs of a blood clot include swelling, pain, or redness in the arm or leg, chest pain, or shortness of breath. Seek medical attention right away if you experience any of these symptoms.

Proteinuria

Votrient may cause proteinuria, which is a condition where protein is present in the urine. Signs of proteinuria include foamy or frothy urine. If you experience these symptoms, contact your doctor.

GI perforation and fistula

Votrient can sometimes cause a serious condition called GI perforation and fistula which can be life-threatening. This happens when a hole or abnormal passage forms in the gastrointestinal (GI) tract, which can cause symptoms like severe stomach pain, nausea, and vomiting. Your doctor will monitor you closely while you are taking it and may perform regular tests to check for signs of this condition. If you experience symptoms like severe stomach pain or vomiting, contact your doctor right away.

Tumor Lysis syndrome

Votrient can sometimes cause a condition called tumor lysis syndrome. This happens when cancer cells break down quickly and release harmful substances into the body. It can cause problems like kidney damage, heart problems, and abnormal blood tests. Your doctor will monitor you closely and may give you medications to help prevent this from happening. If you experience symptoms like weakness, nausea, or swelling, contact your doctor right away.

Infection

Votrient can weaken the body’s immune system, making it harder to fight off infections. This means that people taking Votrient may be more susceptible to infections like colds, the flu, or other illnesses. It is important to practice good hygiene, such as washing your hands regularly, avoiding contact with sick people, and getting vaccinated, to reduce the risk of infection. If you develop symptoms of an infection, such as fever or cough, contact your doctor right away.

Infertility

Votrient can affect fertility for men and women. If you are trying to conceive or plan to conceive, consult with your doctor before taking.

Pregnant or Planning to Become Pregnant

Votrient during pregnancy can severely harm your unborn child. It is recommended to use effective contraceptive. If you are pregnant or become pregnant while taking it, contact your doctor immediately.

Breastfeeding

It is not known if this medication passes into breast milk however it is not recommended to take it while breastfeeding. If you are breastfeeding or considering breastfeeding while taking Votrient, talk to your doctor for the best course of action before taking it.

Interactions & Contraindications

Before using Votrient, tell your doctor or pharmacist if you take any medications, herbal supplements, or vitamins.

Grapefruit

Taking Votrient while consuming grapefruit or grapefruit juice can increase the potency. This effect can lead to an increase of side effects.

Blood thinners

Taking  it with blood thinners, such as warfarin, can increase the risk of bleeding. Blood thinners work by slowing down the blood’s ability to clot, which can be helpful in some situations. However, taking Votrient with a blood thinner can further increase this effect, which can lead to serious bleeding problems. Consult with your doctor to determine if a change of therapy is needed.

Antacids

Taking Votrient with antacids can decrease the effectiveness. Antacids work by reducing stomach acid levels, which can affect how well it is absorbed by the body. If you need to take an antacid while on Votrient, your doctor may recommend that you take it at least 2 hours before or 2 hours after taking it to minimize the interaction.

The active ingredient in  Votrient is pazopanib.

Votrient may contain the following inactive ingredients: magnesium stearate, microcrystalline cellulose, povidone, sodium starch glycolate, hypromellose, iron oxide black, macrogol/polyethylene glycol 400 (PEG 400), polysorbate 80, and titanium dioxide.

Votrient is a prescription drug used to treat advanced kidney cancer and soft tissue sarcoma.

Votrient belongs to a class of drugs known as tyrosine kinase inhibitors, which work by blocking the action of certain enzymes that promote the growth of cancer cells.

Votrient is usually taken orally once daily, with or without food, as directed by your doctor.

The recommended dosage of Votrient may vary depending on the type of cancer being treated and other factors. The typical dose is 800mg once daily. Your doctor will determine the appropriate dose for you.

Votrient can interact with certain medications, so it’s important to inform your doctor about all the medications you are currently taking.

Common side effects of Votrient include nausea, diarrhea, high blood pressure, fatigue, and skin rash. Rare but serious side effects may also occur, such as liver problems and blood clots.

The time it takes for Votrient to start working varies depending on the individual and the type of cancer being treated. Your doctor will monitor your progress and determine whether the treatment is effective.

Votrient can cause harm to a developing fetus, so it is not recommended for use during pregnancy. It is recommended to use effective contraceptives during treatment.

It is not known if Votrient passes into breast milk, however it is not recommended for use while breastfeeding.

Votrient has not been studied in children, so its safety and effectiveness in pediatric patients have not been established.

Votrient is not a cure for cancer, but it can help to slow or stop the growth of cancer cells.

Votrient is currently approved for the treatment of advanced kidney cancer and soft tissue sarcoma. Its effectiveness in other types of cancer is not yet known.

If you miss a dose of Votrient, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule.

No, you should not stop taking Votrient without first consulting your doctor, even if you feel better. Stopping the medication prematurely may allow the cancer to grow and spread.

Votrient can be used for long-term treatment, as directed by your doctor. Your doctor will monitor you regularly for any potential side effects.

If you experience any side effects from Votrient, contact your doctor right away. Your doctor may adjust your dose or recommend other treatments to help manage your symptoms.

Votrient may interact with grapefruit or grapefruit juice, which can increase the risk of side effects. Inform your doctor of all medications you are taking to reduce the side effects and impact.

Drinking alcohol while taking Votrient can increase the risk of liver damage and may also increase the risk of certain side effects, such as dizziness or drowsiness. It is important to avoid drinking alcohol or to limit your alcohol intake as recommended by your healthcare provider.

Yes, you can purchase Votrient online. Buying medications online is convenient and often less expensive than purchasing at your local pharmacy.