Have a prescription? Buy Yuflyma from Canada and experience numerous benefits, including:

  • Major Cost Savings: Purchase Yuflyma at lower prices compared to the US.
  • Bulk Discounts: Enjoy additional savings with bulk orders of Yuflyma.
  • Reliable Express Delivery: Fast and efficient shipping directly to your doorstep.
  • Secure Online Ordering: Order online or by phone at 1-888-513-2294
Buy Yuflyma from Canada
Get notified when Yuflyma back in stock

Fill out the form below and get notified when Yuflyma is back in stock and receive a one-time 10% OFF coupon code.

Yuflyma is a significant advancement in the treatment of various autoimmune conditions. It is recognized as a biosimilar to Humira (Adalimumab), one of the most widely used biologic medications in the world. The introduction of Yuflyma offers a more accessible treatment option for patients, maintaining the efficacy and safety profile similar to that of its reference product, Humira. This development marks a pivotal moment in the healthcare industry, particularly in the realm of affordable biologic therapies.

What is Yuflyma?

Yuflyma’s generic name is adalimumab-aaty, and it’s pronounced as “yoo-fly’-mah.” As a TNF (Tumor Necrosis Factor) blocker, Yuflyma plays a crucial role in modulating the immune system. TNF is a protein in the body that contributes to inflammation and is implicated in various autoimmune disorders. By inhibiting TNF, Yuflyma effectively reduces inflammatory responses, which are a hallmark of autoimmune diseases. This mechanism of action positions Yuflyma as a vital therapeutic agent in managing these conditions.

Medical Uses

Yuflyma is approved for treating a range of autoimmune conditions, each with its unique challenges and impacts on patients’ lives. These include:

  1. Rheumatoid Arthritis: Yuflyma helps in reducing pain, swelling, and progression of joint damage in adults with moderate to severe rheumatoid arthritis. It can be used alone or in combination with methotrexate.
  2. Juvenile Idiopathic Arthritis: For children aged two years and older, Yuflyma is used to alleviate the symptoms of this form of arthritis, which affects multiple joints.
  3. Psoriatic Arthritis: In adults, Yuflyma is effective in managing the symptoms of psoriatic arthritis, a condition that combines skin symptoms of psoriasis with joint inflammation.
  4. Ankylosing Spondylitis: This medication is used to reduce the signs and symptoms of this inflammatory disease, primarily affecting the spine and large joints.
  5. Crohn’s Disease: Yuflyma is beneficial for adults and children aged six years and older with this inflammatory bowel disease, helping to reduce symptoms and prevent flare-ups.
  6. Ulcerative Colitis: In adults with this form of inflammatory bowel disease, Yuflyma helps in reducing symptoms and achieving and maintaining remission.
  7. Plaque Psoriasis: For adults with moderate to severe chronic plaque psoriasis, Yuflyma is used when systemic therapy or phototherapy is necessary.
  8. Hidradenitis Suppurativa: Yuflyma treats this chronic skin condition, characterized by small, painful lumps under the skin, in adults.

In each of these conditions, Yuflyma’s role as a TNF blocker is pivotal in reducing inflammation and improving quality of life for patients.

How Yuflyma Works

Yuflyma operates by targeting and inhibiting the activity of Tumor Necrosis Factor (TNF), a substance in the body’s immune system responsible for inflammation and immune system regulation. TNF plays a critical role in the inflammatory process of autoimmune diseases. In such conditions, the body’s immune system mistakenly attacks its own tissues, leading to inflammation and tissue damage.

Yuflyma binds to TNF molecules, preventing them from interacting with their receptors on cell surfaces. This inhibition blocks the cascade of inflammatory responses triggered by TNF, thereby reducing inflammation and alleviating symptoms associated with autoimmune disorders. By targeting TNF, Yuflyma helps in managing the overactive immune response, making it a valuable treatment for various autoimmune conditions.

Dosage and Administration

Yuflyma is available in two forms: a pre-filled syringe and an auto-injector, providing flexibility and convenience in administration. The dosage and administration of Yuflyma vary depending on the condition being treated:

  • Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis: The typical dosage is 40 mg administered every other week.
  • Crohn’s Disease, Ulcerative Colitis: The initial dosage is higher, followed by a maintenance dose.
  • Plaque Psoriasis, Hidradenitis Suppurativa: Dosage may vary, often starting with a higher dose followed by a regular maintenance dose.

Patients or caregivers are trained to administer Yuflyma subcutaneously, usually in the thigh or abdomen. It’s important to rotate the injection site with each dose to avoid skin issues. The medication should be allowed to reach room temperature before injection for patient comfort.

Side Effects

Common Side Effects

The most frequently reported side effects of Yuflyma include:

  • Injection site reactions (redness, itching, swelling)
  • Upper respiratory infections (like colds)
  • Headaches
  • Nausea
  • Rash

These side effects are generally mild and often resolve without needing to discontinue the medication.

Serious Side Effects and Allergic Reactions

Serious side effects, though less common, can include:

  • Severe infections such as tuberculosis and fungal infections
  • Allergic reactions, which may manifest as hives, difficulty breathing, or swelling of the face
  • Neurological symptoms like numbness or tingling, which could indicate nerve problems

Immediate medical attention should be sought if any of these serious side effects occur.

Long-term Risks

Long-term use of Yuflyma may increase the risk of certain serious conditions, including:

  • Increased susceptibility to infections due to immune system suppression
  • Potential increased risk of developing certain types of cancer, such as lymphoma
  • Reactivation of hepatitis B in carriers of the virus

Patients on Yuflyma should be monitored regularly for these risks, and any concerns should be promptly discussed with a healthcare provider.

Warnings and Precautions

Risks Associated with Yuflyma

Yuflyma, like other TNF blockers, carries several risks that require careful consideration:

  • Infections: Patients are at an increased risk for serious infections, including tuberculosis, fungal, bacterial, and viral infections. These infections may lead to hospitalization or death.
  • Malignancies: There is a potential risk of developing certain types of cancer, such as lymphoma and other malignancies, particularly in children and adolescents.
  • Heart Failure: Worsening or new onset of heart failure has been reported.
  • Neurological Disorders: Rare cases of neurological disorders, including multiple sclerosis and seizures, have been associated with TNF blockers.
  • Autoimmune Reactions: Treatment may result in the formation of autoantibodies and, in rare cases, a lupus-like syndrome.

Conditions Under Which Yuflyma Should Not Be Used

Yuflyma should not be used in patients with:

  • Active Tuberculosis: Patients should be tested for TB before starting Yuflyma.
  • Severe Infections: Including sepsis, active fungal infections, and other opportunistic infections.
  • Known Hypersensitivity: To any component of the product.

Necessary Medical Tests Before and During Treatment

Before initiating treatment with Yuflyma, patients should undergo:

  • Screening for Latent Tuberculosis: Using a tuberculin skin test or a TB blood test.
  • Tests for Hepatitis B: To prevent reactivation in carriers.
  • Regular Monitoring: For signs of infection, malignancy, heart failure, and neurological symptoms.

Interactions with Other Medications

Information on Drug Interactions

Yuflyma can interact with:

  • Live Vaccines: Patients should not receive live vaccines while using Yuflyma.
  • Other TNF Blockers or Biologics: Concurrent use with other biologics or TNF blockers can increase the risk of infections.
  • Cytochrome P450 Substrates: As Yuflyma may impact the levels of these drugs.

Special Considerations for Biologic Products

Care should be taken when switching from or to other biologic products, as overlapping biological activity may increase risks.

Use in Specific Populations

Considerations for Use in Children, Elderly, Pregnant or Breastfeeding Women

  • Children: Safety and efficacy have been established for certain conditions in pediatric patients.
  • Elderly: Older patients may be more susceptible to infections.
  • Pregnant Women: Yuflyma should be used during pregnancy only if clearly needed. The effects on the developing fetus are not fully known.
  • Breastfeeding Women: Caution should be exercised when Yuflyma is administered to breastfeeding women, as it is not known if the drug is excreted in human milk.

Storage and Handling

Proper Storage Conditions

  • Refrigeration: Yuflyma should be stored in a refrigerator at 2°C to 8°C (36°F to 46°F).
  • Protection from Light: Keep the product in the original carton until ready for use to protect from light.
  • Avoid Freezing: Do not freeze the medication.

Handling and Disposal of the Medication

  • Handling: Allow the medication to reach room temperature before administration for patient comfort.
  • Disposal: Used syringes and needles should be placed in a puncture-resistant container and disposed of in accordance with local regulations. Do not reuse or share syringes and needles.

Frequently Asked Questions

Yuflyma is a medication used to treat various autoimmune conditions like rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, ulcerative colitis, plaque psoriasis, and hidradenitis suppurativa. It works by inhibiting TNF, a substance in the body that causes inflammation, thereby reducing symptoms and preventing disease progression.

Yuflyma is administered as a subcutaneous injection, meaning it’s injected under the skin. It is available in pre-filled syringes and auto-injectors for convenience. Patients or caregivers can administer Yuflyma themselves after receiving proper training on injection techniques from healthcare professionals.

Common side effects of Yuflyma include injection site reactions (like redness and swelling), upper respiratory infections, headaches, and nausea. These side effects are generally mild and often resolve without needing to discontinue the medication.

The effects of Yuflyma during pregnancy are not fully known. It should be used during pregnancy only if clearly needed. Pregnant women should discuss the potential risks and benefits with their healthcare provider before starting or continuing treatment with Yuflyma.

Yuflyma is approved for use in children for certain conditions, such as juvenile idiopathic arthritis. However, the safety and effectiveness can vary based on the child’s age and the specific condition being treated. Consult a pediatrician for advice tailored to your child’s health needs.

Yuflyma works by targeting and neutralizing TNF, a key factor in the inflammatory process of autoimmune diseases. By inhibiting TNF, Yuflyma reduces inflammation and alleviates symptoms associated with autoimmune disorders, helping to manage the overactive immune response.

While on Yuflyma, it’s advised to avoid live vaccines as the medication can weaken the immune system. Non-live vaccines can generally be received, but it’s best to consult with your healthcare provider for specific recommendations based on your health status.

If you miss a dose of Yuflyma, administer it as soon as you remember. Then, return to your regular dosing schedule. Do not double the dose to make up for the missed one. If you’re unsure, consult your healthcare provider for guidance.

Yes, Yuflyma can increase the risk of serious infections, including tuberculosis and fungal infections, due to its immune-suppressing effects. Patients should be tested for latent tuberculosis before starting Yuflyma, and monitored for signs of infection during treatment.

Yuflyma may interact with other medications, especially other biologics and TNF blockers. It’s important to inform your healthcare provider about all medications you’re taking to avoid potential drug interactions.

Yuflyma should be stored in a refrigerator at 2°C to 8°C (36°F to 46°F). It should not be frozen and should be protected from light. If needed, it can be allowed to reach room temperature before injection for patient comfort.

Yes, Yuflyma can cause allergic reactions, though this is rare. Symptoms may include hives, difficulty breathing, and swelling of the face. If you experience these symptoms, seek immediate medical attention.

Long-term use of Yuflyma may increase the risk of certain conditions like infections and malignancies, including lymphoma. Regular monitoring and consultations with your healthcare provider are essential to manage these risks.

There are no specific warnings against alcohol consumption while taking Yuflyma, but it’s always wise to moderate alcohol intake, especially if you have a chronic health condition. Discuss with your healthcare provider for personalized advice.

The time it takes for Yuflyma to start working can vary. Some patients may notice improvements in symptoms within a few weeks, while for others, it may take several months. Consistent use as prescribed is important for the best results.

Yuflyma is approved for specific autoimmune conditions. Using it for other conditions is not recommended unless advised by a healthcare provider. Off-label use should only be considered under professional medical guidance.

While using Yuflyma, take precautions to reduce the risk of infections, such as practicing good hygiene and avoiding close contact with people who are sick. Regular check-ups and monitoring for any unusual symptoms are also important.

Yuflyma can exacerbate or cause new-onset heart failure in rare cases. If you have a history of heart disease, discuss the risks with your healthcare provider before starting treatment.

If you experience side effects from Yuflyma, contact your healthcare provider. They can provide advice on managing the side effects or adjusting your treatment plan if necessary.

Elderly patients can use Yuflyma, but they may be at higher risk for infections. It’s important for elderly patients to be closely monitored by their healthcare providers while on Yuflyma therapy.